scholarly journals Risk factors for myocardial infarction in young women.

1976 ◽  
Vol 30 (2) ◽  
pp. 94-100 ◽  
Author(s):  
J I Mann ◽  
R Doll ◽  
M Thorogood ◽  
M P Vessey ◽  
W E Waters
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Young Women

P-45 Risk factors for sudden cardiac death in young women after myocardial infarction

Resuscitation ◽  
1996 ◽  
Vol 31 (3) ◽  
pp. S32
Author(s):  
J. Kloś ◽  
S. Karczmarewicz ◽  
P. Kulakowski ◽  
J. Kociszewska ◽  
L. Ceremużyński
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Sudden Cardiac Death ◽  
Young Women ◽  
Cardiac Death

scholarly journals A levels of endogenous gonadal hormones and their relationship with selected coronary artery disease risk factors among young women post myocardial infarction.

2011 ◽  
Vol 58 (3) ◽  
Author(s):  
Urszula Ablewska ◽  
Krzysztof Jankowski ◽  
Ewa Rzewuska ◽  
Danuta Liszewska-Pfejfer ◽  
Tomasz Hryniewiecki
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Young Women ◽  
Luteal Phase ◽  
Follicle Stimulating Hormone ◽  
Gonadal Hormones ◽  
Artery Disease ◽  
Mean Concentration ◽  
Cad Risk

In recent decades a significant raise in the incidence of myocardial infarction among young women has been recorded. It is presumed that, apart from the classical risk factors, other reasons exist for premature atherosclerosis in young women, related to the homeostasis of gonadal hormones. The aim of the study was to analyze the levels of gonadal hormones (estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone, testosterone and dehydroepiandrosterone) measured in the luteal phase, in 65 normally menstruating women post myocardial infarction (MI) and to investigate a possible relationship between the hormone profile and selected coronary artery disease (CAD) risk factors. The levels of gonadal hormones: estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone, testosterone and dehydroepiandrosterone were measured in the luteal phase. All examined women had normal mean levels of gonadal hormones. In the post MI patients leading a sedentary life style, a significantly lower mean progesterone concentration was observed (16.29 ± 9.11 versus 29.43 ± 21.14 nmol/l, p < 0.05) and significantly higher mean testosterone concentration (2.34 ± 0.98 versus 1.76 ± 1.09 nmol/l, p < 0.05) when compared to patients from the same group, but leading a more active life. In obese post MI women (BMI ≥ 30 kg/m(2)) a lower mean concentration of progesterone was detected (18.02 ± 8.12 versus 26.16 ± 14.72 nmol/l, p < 0.05), than in slimmer patients from the same group. In post MI women with a positive family history for CAD, a significantly higher mean concentration of testosterone was detected (2.31 ± 1.22 versus 1.67 ± 0.74 nmol/l, p < 0.05) than in patients with no family history. The results suggest a correlation between levels of gonadal hormones and classical CAD risk factors.

RISK FACTORS FOR MYOCARDIAL INFARCTION IN YOUNG WOMEN

1987 ◽  
Vol 125 (5) ◽  
pp. 832-843 ◽  
Author(s):  
CARLO LA VECCHIA ◽  
SILVIA FRANCESCHI ◽  
ADRIANO DECARLI ◽  
SANDRO PAMPALLONA ◽  
GIANNI TOGNONI
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Young Women

Risk factors in young women with acute myocardial infarction

1994 ◽  
Vol 23 (3) ◽  
pp. 627
Author(s):  
A. Ciccone ◽  
A. Nashed ◽  
M. Lin ◽  
S. Cecere
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Young Women

scholarly journals Prothrombotic gene variants as risk factors of acute myocardial infarction in young women

2012 ◽  
Vol 10 (1) ◽  
pp. 235 ◽  
Author(s):  
Rossella Tomaiuolo ◽  
Chiara Bellia ◽  
Antonietta Caruso ◽  
Rosanna Di Fiore ◽  
Sandro Quaranta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Young Women ◽  
Gene Variants

scholarly journals A Common Prothrombin Variant (20210 G to A) Increases the Risk of Myocardial Infarction in Young Women

Blood ◽  
1997 ◽  
Vol 90 (5) ◽  
pp. 1747-1750 ◽  
Author(s):  
F.R. Rosendaal ◽  
D.S. Siscovick ◽  
S.M. Schwartz ◽  
B.M. Psaty ◽  
T.E. Raghunathan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Confidence Interval ◽  
Young Women ◽  
Odds Ratio ◽  
Factor V Leiden ◽  
Clotting Factor ◽  
Factor V ◽  
Coronary Risk Factors ◽  
Factor Ii

Abstract Using specimens from a population-based case control study among women ages 18 to 44 years in western Washington, we assessed the relationship between carriership of a genetic clotting factor II variant (20210 G→A) and myocardial infarction (MI). The factor II variant was previously shown to be present in 1% to 2% of the population, to increase the levels of factor II, and to be associated with venous thrombotic disease. Personal interviews and blood samples were obtained from 79 women with a first myocardial infarction and 381 control women identified through random-digit telephone dialing. Polymerase chain reaction (PCR) method was used to determine the factor II genotypes. The factor II 20210 G to A transition was present more often in women with MI (5.1%) than among control women (1.6%). The age-adjusted odds ratio for MI was 4.0 (95% confidence interval 1.1 to 15.1). The relative risk was high when another major cardiovascular risk factor was also present, such as smoking (odds ratio 43.3, 95% confidence interval 6.7 to 281), and the risk seemed limited to those with other risk factors. These results, in which the effect of major coronary risk factors is enhanced fourfold to sixfold by the prothrombin variant, are similar to those previously reported for another genetic clotting abnormality, factor V Leiden. We conclude that factor II 20210 G to A increases the risk of myocardial infarction in young women, especially in the women with other major risk factors for coronary heart disease.

scholarly journals Does thrombolytic therapy harm or help in ST elevation myocardial infarction (STEMI) caused by the spontaneous coronary dissection?

2015 ◽  
Vol 72 (6) ◽  
pp. 536-540 ◽  
Author(s):  
Zoran Jovic ◽  
Slobodan Obradovic ◽  
Nemanja Djenic ◽  
Zorica Mladenovic ◽  
Predrag Djuric ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Thrombolytic Therapy ◽  
Young Women ◽  
Anterior Wall ◽  
Artery Dissection ◽  
Coronary Artery Dissection ◽  
Medial Segment

Introduction. Spontaneous coronary artery dissection (SCAD) is a very rare disease with poor prognosis. It mainly affects young women free of risk factors for coronary artery disease (CAD) and women during the peripartum period. The prognosis for myocardial infarction caused by SCAD is poor, management is often difficult and guidelines still missing. Case report. We presented a woman with acute myocardial infarction of anterior wall of the left ventricle, caused by spontaneous dissection of medial segment of the left anterior descending coronary artery. We treated the patient with thrombolytic therapy and performed coronary angiography after that. Finally we decided to do nothing more. Two years later we performed coronary angiography again and founded the coronary artery normal. We also analyzed 19 cases publiched from 1996 to 2012 when coronary artery dissection had been treated with thrombolytic agent. Analysis revealed only one case of 19, with complication after treating SCAD with thrombolysis. Conclusion. Sometimes, regarding myocardial infarction in young women with no risk factors for CAD, especially in young women in peripartum, we should think about SCAD. The presented case, like eight others, demonstrates that good clinical outcomes can be achieved with thrombolysis. In spite of all this, we still need more data to verify that thrombolysis does not have to harm the therapy for SCAD. For the time being thrombolytic therapy could be an option.

Platelet glycoprotein IIb polymorphism, traditional risk factors and non-fatal myocardial infarction in young women

2001 ◽  
Vol 112 (3) ◽  
pp. 632-636 ◽  
Author(s):  
Alexander P. Reiner ◽  
Stephen M. Schwartz ◽  
Prasanna N. Kumar ◽  
Frits R. Rosendaal ◽  
Rachel M. Pearce ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Young Women ◽  
Platelet Glycoprotein ◽  
Traditional Risk Factors ◽  
Fatal Myocardial Infarction

scholarly journals Spontaneous Coronary Artery Dissection/Intramural Haematoma in Young Women with ST-Elevation Myocardial Infarction: “It Is Not Always a Plaque Rupture Event”

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
George Kassimis ◽  
Athanasios Manolis ◽  
Jonathan N. Townend
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery ◽  
Young Women ◽  
St Elevation Myocardial Infarction ◽  
Artery Dissection ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
St Elevation ◽  
Conventional Risk Factors

Spontaneous coronary artery dissection (SCAD) is an unusual, but increasingly recognized, cause of ST-elevation myocardial infarction (STEMI), especially among younger patients without conventional risk factors for coronary artery disease (CAD). Although dissection of the coronary intima or media is a hallmark finding, hematoma formation within the vessel wall is often present. It remains unclear whether dissection or hematoma is the primary event, but both may cause luminal stenosis and occlusion. The diagnosis of SCAD is made principally with invasive coronary angiography, although adjunctive intracoronary imaging modalities may increase the diagnostic yield. In STEMI patients, the decision whether to pursue primary percutaneous coronary intervention (PCI) or appropriate conservative medical therapy is based on clinical presentation, the extent of the dissection, the critical anatomy involvement, and the amount of ischaemic myocardium at risk. In this case report, we present two cases of young women with SCAD and STEMI, successfully treated with primary PCI. We briefly illustrate the characteristic aspects of the angiographic presentation and intravascular ultrasound-guided treatment. SCAD should always be considered in young STEMI patients without conventional risk factors for CAD with primary angioplasty to be required in patients with ongoing myocardial ischemia.

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