scholarly journals P2-173 Chronic diseases: studying and understanding outcome using routine data: chronic kidney disease (CKD), an example

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A269-A269
Author(s):  
A. Marks ◽  
N. Fluck ◽  
G. Prescott ◽  
A. MacLeod ◽  
W. C. S. Smith ◽  
...  
2016 ◽  
Vol 6 (2) ◽  
pp. 53-62
Author(s):  
Jeta Ajasllari

The aim of this study was to evaluate the effectiveness of an intervention with CBT in patients with chronic renal disease. The study findings are in the context of previous researches and existing theories. Searches were done in the professional literature related to different chronic diseases and respectively with Chronic Kidney Disease in children and adolescents. Many paediatric chronic diseases are difficult to be managed because of the limitations caused by the disease itself; consequently, some of them need to be subjected to painful and difficult medical procedures as well. Respectively, for children diagnosed with CKD life changes completely because of limitations, mainly physical ones, due to the characteristics of the disease which require constant adaption as well as development of strategies to face the disease. Their behaviours must change accordingly as part of a new life of self-care. Cognitive-Behavioural Therapy is a psychological therapy, which has been investigated extensively and has been found as very effective to reduce psychological symptoms caused by the disease. This therapy integrates the modification of behaviour with the cognitive restructuring, the aim of which is to change the patient’s unhealthy behaviours through cognitive and behaviour techniques. Keywords: children; chronic kidney disease; cognitive behavioural therapy


2020 ◽  
Vol 16 (3) ◽  
pp. 39-43
Author(s):  
I.O. Dudar ◽  
O.M. Loboda ◽  
І.V. Krasyuk ◽  
V.V. Alekseeva

Relevance. Chronic diseases have a long duration and a rather slow progression, and people who have such diseases want not only to live longer but also to live better. Therefore, quality of life (QOL) is one of the most important health issues for the treatment of chronic diseases. Objective: to determine the features of QOL in patients with chronic kidney disease (CKD) stage II-IV. Materials and methods. In 171 patients with CKD of II-IV centuries, in addition to general clinical and laboratory studies, QOL was studied using a questionnaire to assess the quality of life of SF-36. The questionnaire contains 36 questions of the main module, supplemented by multi-point scales aimed specifically at patients with CKD. The answers were evaluated in points - from 0 to 100. The higher the score, the better the patient's QOL. The total components were also calculated: physical total component, mental total component, total points. The obtained research data were subjected to statistical processing, which included parametric (t-test for samples with unrelated variants) and non-parametric (Mann-Whitney method) methods, correlation analysis was used. Results. Most QOL indicators worsen significantly with the progression of CKD. The indicators of total QOL, as well as the indicator "the impact of the disease on everyday life" are most significantly reduced. Age correlates as much as possible with most indicators of QOL in patients with CKD. With age, the QOL of patients decreases, but the manifestations of the disease increase and the mental and physical condition of patients deteriorate. QOL parameters are probably directly and moderately correlated with hemoglobin levels. Most QOL parameters are significantly moderately correlated with systolic blood pressure and diastolic blood pressure. It is assumed that the correction of anemia and blood pressure control, in addition to a positive effect on disease progression and the occurrence and development of complications, will also improve QOL. There were no significant differences in the assessment of QOL in men and women. Conclusions. QOL indicators decrease with the progression of CKD. Age, hemoglobin level, blood pressure affect QOL.


2018 ◽  
Vol 1 (4) ◽  
Author(s):  
Ankang Li ◽  
Qun Zuo

Objective A new view is proposed for the mechanism of exercise prevention and improvement of chronic disease, that exercise may play a role by promoting the expression of anti-aging protein α-Klotho. Methods By means of literature review and prospective analysis, this paper summarizes the research status of the application of exercise in the prevention and improvement of chronic diseases and the effects of anti-aging protein α-Klotho on chronic cardiovascular disease, diabetes, chronic kidney disease and cancer and other chronic diseases and the effect of exercise on the expression of plasma α-Klotho and its possible mechanism. The research prospects of exercise to interfere with chronic diseases by promoting the expression of α-Klotho are envisioned Results (1) At present, the incidence and mortality of chronic diseases are high on a global scale. With the development of aging, chronic diseases will cause a serious economic burden and great waste of resources. Therefore, research on how to prevent and treat chronic diseases related to aging and lifestyle has become a top priority. Strong evidence suggests that exercise is an economical and efficient way to slow down the progress of some chronic diseases and to control symptoms such as diabetes, chronic kidney disease, heart failure, cardiovascular disease, and so on. However, we have not fully understood the cellular and molecular mechanisms underlying the effects of exercise.(2) α-Klotho is an anti-aging protein that regulates calcium and phosphorus metabolism, inhibits Wnt signaling, inhibits oxidative stress, and inhibits tumor and fibrosis. It has been proved to play an important role in the occurrence and development of chronic diseases such as chronic cardiovascular disease, diabetes, chronic kidney disease, tumor and other chronic diseases.(3) Exercise has been proved to be effective in promoting the expression of plasma α-Klotho protein, and the degree of response may be related to physical fitness and age. However, the mechanism of exercise to promote the expression of α-Klotho protein has not been reported. Combined with the existing research results, it is presumed that it may be related to DNA methylation, Peroxisome proliferator-activated receptor gamma(PPARγ) signal transduction and vitamin D receptor.  Conclusions Exercise has gradually become an important way to intervene in chronic diseases, but the lack of understanding of its mechanism hinders the development of exercise in the field of prevention and treatment of chronic diseases. It is found that exercise can promote the expression of plasma α-Klotho protein, and the expression of α-Klotho protein will be beneficial to the prevention and improvement of chronic diseases such as chronic cardiovascular disease, diabetes, chronic kidney disease and tumor. Therefore, it is speculated that promoting the expression of α-Klotho may be one of the mechanisms of exercise prevention and improvement of chronic diseases, but there is still a research gap on the mechanism of exercise promoting α-Klotho expression. In addition, the current research on the expression of plasma α-Klotho is aimed at healthy people, and the effect of exercise on the expression of α-Klotho in chronic diseases, such as chronic cardiovascular disease, diabetes, chronic kidney disease, is also needed to be studied more. The study of the mechanism of exercise prevention and improvement of chronic diseases provides a theoretical basis for the selection and formulation of related exercise programs, and may provide new ideas for the development of new drugs for chronic diseases. Therefore, studies on exercise to interfere with chronic diseases by promoting the expression of α-Klotho have good research prospects.


Global Heart ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. 461
Author(s):  
A.G.D.S. Galil ◽  
B.A.B.B. Andrade ◽  
M.M. Gusmão ◽  
L.R. Araújo ◽  
M.M. Mello ◽  
...  

Author(s):  
Álvaro Alvares de Carvalho César Sobrinho ◽  
Leandro Dias da Silva ◽  
Leonardo Melo de Medeiros ◽  
Maria Eliete Pinheiro

Early diagnosis and slowing the progression of chronic diseases are very important factors for improving the quality of life of people with this type of problem. Chronic Kidney Disease (CKD) is one of these diseases; however, with aggravating factors it can be the consequence of other chronic diseases of high incidence, such as Diabetes Mellitus (DM) and Hypertension. The use of Information and Communication Technologies may be a way to help the doctor provides a diagnosis in less advanced stages of CKD. In this context, a mobile assistant to aid the early diagnosis of CKD through a wireless communication and Coloured Petri Nets (CPNs) models is proposed.


2018 ◽  
Vol 6 (12) ◽  
Author(s):  
María José Vázquez-Atanacio

Currently, the health care methods for chronic diseases are leaving behind the paternalism and the doctor-patient relationship, giving way to a new model, in which people with any chronic disease play an important role in their own health care with the support of the health care provider, this is called self-management. An important aspect of the self-management of diseases is the determination and elaboration of specific strategies in the patient´s empowerment through knowledge, in order to face all the challenges and demands of living with this disease.


Aquichan ◽  
2019 ◽  
Vol 19 (4) ◽  
pp. 1-12
Author(s):  
Vanessa Almeida Maia Damasceno ◽  
Marisa Silvana Zazzetta ◽  
Fabiana de Souza Orlandi

Objective: To translate and culturally adapt the Scale to Measure the Care Ability of Family Caregivers of People with Chronic Diseases to the Brazilian context. Materials and Methods: This is a methodological study that followed the steps recommended by Dorcas Beaton for translating and culturally adapting this scale in Brazil. All ethical precepts have been respected. Results: The first translation of the instrument into Brazilian Portuguese was done by two translators; the consensual version was then established, which was back-translated into Spanish by another independent translator. The committee of specialists comprised seven health professionals, obtaining a content validity index (CVI) = 1.00 in 41 items, CVI = 0.86 in three items and CVI = 0.71 in four items. After adjusting the seven items, a pretest was applied to 14 family caregivers of people with chronic kidney disease. Based on this, the participants’ difficulties were observed, and then the items were reviewed. Conclusions: After the translation and adaptation process was completed, the Brazilian version of the instrument entitled “Scale to Measure the Care Ability of Family Caregivers of People with Chronic Diseases” was obtained.


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