scholarly journals p53 protein expression in central nervous system neoplasms.

1992 ◽  
Vol 45 (7) ◽  
pp. 583-586 ◽  
Author(s):  
M Barbareschi ◽  
P Iuzzolino ◽  
A Pennella ◽  
A Allegranza ◽  
G Arrigoni ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Protein Expression ◽  
P53 Protein ◽  
Central Nervous System Neoplasms ◽  
P53 Protein Expression ◽  
Nervous System Neoplasms

scholarly journals An Update on Neurofibromatosis Type 1-Associated Gliomas

Cancers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 114 ◽  
Author(s):  
Lobbous ◽  
Bernstock ◽  
Coffee ◽  
Friedman ◽  
Metrock ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Autosomal Dominant ◽  
Neurofibromatosis Type ◽  
Central Nervous System Neoplasms ◽  
Therapeutic Landscape ◽  
Nervous System Neoplasms ◽  
Collaborative Efforts

Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome that affects children and adults. Individuals with NF1 are at high risk for central nervous system neoplasms including gliomas. The purpose of this review is to discuss the spectrum of intracranial gliomas arising in individuals with NF1 with a focus on recent preclinical and clinical data. In this review, possible mechanisms of gliomagenesis are discussed, including the contribution of different signaling pathways and tumor microenvironment. Furthermore, we discuss the recent notable advances in the developing therapeutic landscape for NF1-associated gliomas including clinical trials and collaborative efforts.

Extramedullary Spinal Cord Tumors

2018 ◽  
Author(s):  
J. Bradley Elder ◽  
Ahmed Mohyeldin
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Specific Area ◽  
Spinal Cord Tumors ◽  
Central Nervous System Neoplasms ◽  
Case Presentation ◽  
Presenting Symptoms ◽  
Spine Tumors ◽  
Nervous System Neoplasms

Tumors of the spine that occur within the dura but outside of the spinal cord are characterized as intradural but extramedullary spine tumors. The vast majority of these tumors are benign. This chapter uses a case presentation to present diagnostic and management pearls for this anatomic category of central nervous system neoplasms. These tumors are typically diagnosed due to presenting symptoms including pain or neurologic symptoms that localize the tumor to a specific area of the spine. Management is typically surgical. Some types of tumors are associated with syndromes such as neurofibromatosis. This chapter also discusses potential pitfalls and complications and their management.

Coexpression of Genes Involved in Apoptosis in Central Nervous System Neoplasms

1999 ◽  
Vol 21 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Carol S. Bruggers ◽  
Dan Fults ◽  
Sherrie L. Perkins ◽  
Cheryl M. Coffin ◽  
William L. Carroll
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Neoplasms ◽  
Nervous System Neoplasms
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