scholarly journals Endobronchial ultrasound-guided fine-needle aspiration and liquid-based thin-layer cytology

2006 ◽  
Vol 60 (4) ◽  
pp. 388-391 ◽  
Author(s):  
W A H Wallace ◽  
H M Monaghan ◽  
D M Salter ◽  
M A Gibbons ◽  
K M Skwarski
Keyword(s):  
Thin Layer ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Fine Needle

scholarly journals Utility and diagnostic accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration cytology of mediastinal lesions: Saudi Arabian experience

CytoJournal ◽  
2014 ◽  
Vol 11 ◽  
pp. 19 ◽  
Author(s):  
Emad Raddaoui ◽  
Esam H Alhamad ◽  
Shaesta Naseem Zaidi ◽  
Fatmah F Al-Habeeb ◽  
Maha Arafah
Keyword(s):  
Fine Needle Aspiration ◽  
Mediastinal Mass ◽  
Needle Aspiration ◽  
Histological Diagnosis ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Predictive Values ◽  
Fine Needle ◽  
Nodular Lesions

Objective: The objective of this study is to evaluate the cytological accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) of the mediastinal mass/nodular lesions. Study Design: Over 3½ years from inception at King Khalid University Hospital, a retrospective analysis of the cytological diagnoses of all the EBUS-TFNA procedures performed in 80 patients who had mediastinal mass/nodular enlargement. Cytology results were reviewed and correlated with the histologic follow-up. Results: Of the 80 patients who underwent EBUS-TFNA, 15 cases (18.75%) were positive for malignancy, 48 cases (60%) negative for malignancy and 17 cases (21.25%) unsatisfactory. Of the 48 cases, which were negative for malignancy, 24 (50%) cases were of granulomatous inflammation. The overall diagnostic yield of our EBUS-TFNA specimen was 78.75%. Forty-seven cases (58.75%) of 80 cases had histological follow-up biopsies. Among them, 32 cases (68%) had the same cytological and histological diagnosis and 15 cases (31.09%) had discordance between the cytology and the follow-up histological diagnosis. The sensitivity, specificity, and positive and negative predictive values for diagnosing granulomas by EBUS-TFNA are 77%, 82%, 83%, and 75% and for diagnosing malignancy are 71%, 100%, 100%, and 82%, respectively. Conclusion: Preliminary results show that cytological samples obtained through EBUS-TFNA are accurate and specific in making a diagnosis of the mediastinal mass/nodular lesions. Its optimum use depends on the effective collaboration between the cytotechnologist, pathologist, and the bronchoscopist.

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