scholarly journals Radial scar lesions of the breast diagnosed by needle core biopsy: analysis of cases containing occult malignancy

2006 ◽  
Vol 60 (3) ◽  
pp. 295-298 ◽  
Author(s):  
A. G Douglas-Jones ◽  
J. L Denson ◽  
A. C Cox ◽  
I. B Harries ◽  
G. Stevens
Keyword(s):  
Core Biopsy ◽  
Radial Scar ◽  
Needle Core Biopsy ◽  
Occult Malignancy ◽  
Analysis Of Cases

Advocating Nonsurgical Management of Patients With Small, Incidental Radial Scars at the Time of Needle Core Biopsy: A Study of 77 Cases

2015 ◽  
Vol 139 (9) ◽  
pp. 1137-1142 ◽  
Author(s):  
Cathleen Matrai ◽  
Timothy M. D'Alfonso ◽  
Lindsay Pharmer ◽  
Michele B. Drotman ◽  
Rache M. Simmons ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Core Biopsy ◽  
Carcinoma In Situ ◽  
Invasive Carcinoma ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Radial Scar ◽  
Needle Core Biopsy ◽  
Ductal Hyperplasia

Context Radial scars are benign sclerosing lesions that are routinely excised when diagnosed in a needle core biopsy. Optimal management for patients with incidental and small (≤5 mm) radial scars is uncertain. Objective To assess pathologic upgrade of radial scars diagnosed in needle core biopsy samples and identify a subset of patients who could benefit from conservative management. Design Patients with a diagnosis of radial scar in a needle core biopsy who underwent excision of the biopsied area were identified. Radial scars greater than 5 mm in size and those with coexisting atypia, carcinoma, and papillary lesions were excluded. After histologic-radiographic correlation, rates of pathologic upgrade were assessed. Results Seventy-seven radial scars diagnosed in 66 patients were included. Overall, 9 of 77 (12%) showed upgrade to a high-risk lesion (6 lobular carcinoma in situ, 2 atypical ductal hyperplasia, 1 atypical lobular hyperplasia), while none (0%) showed upgrade to invasive carcinoma or ductal carcinoma in situ. One of 22 incidental radial scars (4.5%) showed upgrade on excision versus 6 of 36 (16.7%) for radial scars considered to be the radiographic target (P = .23). Older age was associated with upgrade (P < .001). Conclusions No incidental or small (≤5 mm) radial scars excised revealed invasive carcinoma or ductal carcinoma in situ on excision. Provided there is good pathologic-radiologic concordance, it appears reasonable for these patients to be managed conservatively.

scholarly journals Outcome of radial scar/complex sclerosing lesion associated with epithelial proliferations with atypia diagnosed on breast core biopsy: results from a multicentric UK-based study

2019 ◽  
Vol 72 (12) ◽  
pp. 800-804 ◽  
Author(s):  
Emad Rakha ◽  
Francisco Beca ◽  
Mariangela D'Andrea ◽  
Areeg Abbas ◽  
William Petrou-Nunn ◽  
...  
Keyword(s):  
Core Biopsy ◽  
Invasive Carcinoma ◽  
Ductal Carcinoma ◽  
Surgical Excision ◽  
Lobular Neoplasia ◽  
Radial Scar ◽  
Needle Core Biopsy ◽  
Complex Sclerosing Lesion ◽  
Ductal Hyperplasia

AimsThe clinical significance of radial scar (RS)/complex sclerosing lesion (CSL) with high-risk lesions (epithelial atypia) diagnosed on needle core biopsy is not well defined. We aimed at assessing the upgrade rate to ductal carcinoma in situ (DCIS) and invasive carcinoma on the surgical excision specimen in a large cohort with RS/CSL associated with atypia.Methods157 women with a needle core biopsy diagnosis of a RS/CSL with atypia and follow-up histology were studied. Histological findings, including different forms of the atypical lesions and final histological outcome in the excision specimens, were retrieved and analysed, and the upgrade rates for malignancy and for invasive carcinoma were calculated.Results69.43% of the cases were associated with atypical ductal hyperplasia (ADH) or atypia not otherwise classifiable, whereas lobular neoplasia was seen in 21.66%. On final histology, 39 cases were malignant (overall upgrade rate of 24.84%); 12 were invasive and 27 had DCIS. The upgrade differed according to the type of atypia and was highest for ADH (35%). When associated with lobular neoplasia, the upgrade rate was 11.76%. The upgrade rate’s variability was also considerably lower when considering the upgrade to invasive carcinoma alone for any associated lesion.ConclusionsThe upgrade rate for ADH diagnosed on needle core biopsy with RS is similar to that of ADH without RS and therefore should be managed similarly. RS associated with lobular neoplasia is less frequently associated with malignant outcome. Most lesions exhibiting some degree of atypia showed a similar upgrade rate to invasive carcinoma. Management of RS should be based on the concurrent atypical lesion.

Reflex Estrogen Receptor (ER) and Progesterone Receptor (PR) Analysis of Ductal Carcinoma In Situ (DCIS) in Breast Needle Core Biopsy Specimens

2016 ◽  
Vol 40 (8) ◽  
pp. 1090-1099 ◽  
Author(s):  
Christopher J. VandenBussche ◽  
Ashley Cimino-Mathews ◽  
Ben Ho Park ◽  
Leisha A. Emens ◽  
Theodore N. Tsangaris ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Progesterone Receptor ◽  
Ductal Carcinoma In Situ ◽  
Core Biopsy ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Needle Core Biopsy ◽  
Biopsy Specimens

The role of freehand needle core biopsy in the diagnosis of isolated axillary lymphadenopathy

2008 ◽  
Vol 34 (10) ◽  
pp. 1172
Author(s):  
Amit Nair ◽  
S. Jaleel ◽  
V. Sathya ◽  
N. Aluwihare ◽  
B. Isgar
Keyword(s):  
Core Biopsy ◽  
Needle Core Biopsy ◽  
Axillary Lymphadenopathy

scholarly journals Clinical research Technique of transurethral needle core biopsy to confirm invasive bladder cancer staging

2010 ◽  
Vol 3 ◽  
pp. 388-392
Author(s):  
Piotr Chłosta ◽  
Artur A. Antoniewicz ◽  
Tomasz Szopiński ◽  
Jakub Dobruch ◽  
Andrzej Borówka
Keyword(s):  
Bladder Cancer ◽  
Clinical Research ◽  
Core Biopsy ◽  
Cancer Staging ◽  
Invasive Bladder Cancer ◽  
Needle Core Biopsy ◽  
Research Technique ◽  
Bladder Cancer Staging
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