scholarly journals Folic acid and vitamin B12 levels in pregnancy and their relation to megaloblastic anaemia

1964 ◽  
Vol 17 (2) ◽  
pp. 165-174 ◽  
Author(s):  
E. W. Ball ◽  
C. Giles
1964 ◽  
Vol 2 (4) ◽  
pp. 13-14

Mild deficiency of folic acid is common in the later months of normal pregnancy, due apparently to increased demand and in some cases to impaired absorption1. Megaloblastic anaemia from this cause is not rare, but more frequently a lesser degree of deficiency complicates lack of iron, and in such cases the anaemia responds only to the combined administration of both substances. Deficiency of folic acid has been found in patients with accidental haemorrhage and may be found in anaemia in the puerperium.


2015 ◽  
Vol 78 (3) ◽  
pp. 135-143 ◽  
Author(s):  
H.B. Castellanos-Sinco ◽  
C.O. Ramos-Peñafiel ◽  
A. Santoyo-Sánchez ◽  
J. Collazo-Jaloma ◽  
C. Martínez-Murillo ◽  
...  

1958 ◽  
Vol 75 (4) ◽  
pp. 767-772 ◽  
Author(s):  
M.R. Erdberg ◽  
H. Baker ◽  
I. Pasher ◽  
H. Sobotka
Keyword(s):  

BMJ ◽  
1951 ◽  
Vol 1 (4699) ◽  
pp. 158-161 ◽  
Author(s):  
N. S. Conway ◽  
H. Conway

2021 ◽  
Vol 16 (1) ◽  
pp. 79
Author(s):  
Achmad Maralda Ainin Ghifari

Vegan are group of people who have high risk of megaloblastic anaemia because of vitamin B12 and folic acid defi ciency. Purple sweet potato (Ipomoea Batatas L.) and nutritional yeast are rich vitamin B12 and folic acid, therefore can be formulated into healthy food, such as snack bar for vegan. The purpose of this study is to determine the eff ect of purple sweet potato substitution and nutritional yeast addition on acceptability and availability of vitamin B12 and folic acid of snack bar. The type of research of formulation was true experimental design (Complete Randomize Design) with 1 formula control and 2 modifi ed formula. This research was carried out for 3 months (December 2018-March 2019) in Nutrition Laboratory Universitas Airlangga. The panelists are 38 people who affi liated with vegan community Yayasan Buddha Maitreya Surabaya. Statistical analysis used Kruskall Wallis test and Mann Whitney test with 5% signifi cance level. The results of organoleptic test showed that the most preferred formula by panelists was F2 with an average value of 3,6. There are diff erences in terms of smell characteristic (p=0.017) and taste characterictic (p=0.021). F2 have the highest content of vitamin B12 and folic acid, which are 1.58 mcg and 1,62 mcg, respectively, for 50 gram snack bar. The study showed that the best optimization (acceptability and nutrient content) in formula is F2 (substitution of 20% of purple sweet potato and addition 9 g of nutritional yeast). Therefore, snack bar with purple sweet potato substitution and nutritional yeast enrichment is feasible as an alternative healthy snack for vegan.


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