scholarly journals Instantaneous pressure-flow velocity relations of systemic venous return in patients with univentricular circulation

Heart ◽  
1999 ◽  
Vol 82 (3) ◽  
pp. 294-299 ◽  
Author(s):  
R Kaulitz ◽  
P Bergman ◽  
I Luhmer ◽  
T Paul ◽  
G Hausdorf
2005 ◽  
Vol 289 (2) ◽  
pp. H549-H557 ◽  
Author(s):  
Jamie R. Mitchell ◽  
William A. Whitelaw ◽  
Rozsa Sas ◽  
Eldon R. Smith ◽  
John V. Tyberg ◽  
...  

During mechanical ventilation, phasic changes in systemic venous return modulate right ventricular output but may also affect left ventricular function by direct ventricular interaction. In 13 anesthetized, closed-chest, normal dogs, we measured inferior vena cava flow and left and right ventricular dimensions and output during mechanical ventilation, during an inspiratory hold, and (during apnea) vena caval constriction and abdominal compression. During a single ventilation cycle preceded by apnea, positive pressure inspiration decreased caval flow and right ventricular dimension; the transseptal pressure gradient increased, the septum shifted rightward, reflecting an increased left ventricular volume (the anteroposterior diameter did not change); and stroke volume increased. The opposite occurred during expiration. Similarly, the maneuvers that decreased venous return shifted the septum rightward, and left ventricular volume and stroke volume increased. Increased venous return had opposite effects. Changes in left ventricular function caused by changes in venous return alone were similar to those during mechanical ventilation except for minor quantitative differences. We conclude that phasic changes in systemic venous return during mechanical ventilation modulate left ventricular function by direct ventricular interaction.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Dominik Daniel Gabbert ◽  
Christopher Hart ◽  
Michael Jerosch-Herold ◽  
Philip Wegner ◽  
Mona Salehi Ravesh ◽  
...  

1956 ◽  
Vol 185 (2) ◽  
pp. 351-354 ◽  
Author(s):  
James E. Randall ◽  
Ralph W. Stacy

Instantaneous pressure and flow in the femoral artery of the dog were recorded under steady and pulsatile pressure conditions. Static pressure-flow diagrams and dynamic pressure-flow diagrams over the pulse pressure range at different points in the cardiac cycle were constructed. A comparison was made of the flow corresponding to a) normal pulsatile conditions, and b) static pressures equal to the mean of the pulsatile pressures. The static pressure-flow diagrams were consistent with those described by other workers, and were essentially linear in the ranges studied. Changing from steady to pulsating pressures altered the flow from 40.4 ml/min. to 40.9 ml/min. This difference was less than the measurement accuracy of the flow, although statistical analysis indicated significance to 1%. The dynamic pressure-flow diagram appeared as a ‘loop,’ the shape of which indicated that in 12 of 13 animals, the system was mass controlled and the heart rate was higher than the resonant frequency. In the one exception, the phase angle was negligible and the system was apparently in resonance.


Circulation ◽  
1979 ◽  
Vol 60 (5) ◽  
pp. 1091-1096 ◽  
Author(s):  
J G Stevenson ◽  
I Kawabori ◽  
W G Guntheroth ◽  
T K Dooley ◽  
D Dillard

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