Role of lung function testing in the management of mechanically ventilated infants

Introduction: Congenital thoracic arterial anomalies (CTAAs), such as complete or incomplete vascular rings, pulmonary artery sling, and innominate artery compression syndrome, may cause severe tracheomalacia and upper airway obstruction. An obstructive ventilatory pattern at lung function testing (LFT) has been suggested in the presence of CTAA. The severity of obstruction may be evaluated by LFT. Little is known about the use of LFT in newborn infants with CTAA. The aim of our study is to evaluate the role of LFT in CTAA diagnosis.Methods: This is a retrospective study, conducted between February 2016 and July 2020. All CTAA cases for whom LFT was performed preoperatively were considered for inclusion. Tidal volume (Vt), respiratory rate, and the ratio of time to reach the peak tidal expiratory flow over total expiratory time (tPTEF/tE) were assessed and compared to existing normative data. Demographics and CTAA characteristics were also collected.Results: Thirty cases were included. All infants with CTAA showed a significantly reduced Vt and tPTEF/tE, compared to existing normative data suggesting an obstructive pattern.No significant differences were found for LFT between cases with a tracheal obstruction <50% compared to those with tracheal obstruction ≥50%, or between cases with and without symptoms. Sixteen infants (53.3%) had respiratory symptoms related to CTAA. Of these, only two cases had also dysphagia.Conclusion: LFT values were significantly reduced in cases with CTAA before surgery. LFT represents a potential feasible and non-invasive useful tool to guide diagnosis in the suspect of CTAA.

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Lung function testing

Current Paediatrics ◽

10.1016/s0957-5839(05)80051-x ◽

1993 ◽

Vol 3 (2) ◽

pp. 92-95

Author(s):

P. Helms

Keyword(s):

Lung Function ◽

Lung Function Testing ◽

Function Testing

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Lung Function Testing On and Off Dopaminergic Medication in Parkinson's Disease Patients With and Without Dysphagia

Movement Disorders Clinical Practice ◽

10.1002/mdc3.12251 ◽

2015 ◽

Vol 3 (2) ◽

pp. 146-150 ◽

Cited By ~ 6

Author(s):

Tareq Sawan ◽

Mary Louise Harris ◽

Christopher Kobylecki ◽

Laura Baijens ◽

Michel van Hooren ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Lung Function ◽

Lung Function Testing ◽

Dopaminergic Medication ◽

Function Testing

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- Understanding Lung Function and Disease: Performing Accurate Lung Function Testing

Essential Knowledge and Skills for Healthcare Assistants ◽

10.1201/b16365-23 ◽

2017 ◽

pp. 126-135

Keyword(s):

Lung Function ◽

Lung Function Testing ◽

Function Testing

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A case of unexplained dyspnoea: when lung function testing matters!

Breathe ◽

10.1183/20734735.025018 ◽

2018 ◽

Vol 14 (4) ◽

pp. 325-332 ◽

Cited By ~ 2

Author(s):

Pierantonio Laveneziana ◽

Marie-Cécile Niérat ◽

Antonella LoMauro ◽

Andrea Aliverti

Keyword(s):

Lung Function ◽

Lung Function Testing ◽

Function Testing

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Assessing Airway Resistance Using Plethysmography as Lung Function Testing Among Asymptomatic Rheumatoid Arthritis Patients.

International Journal of Pharma and Bio Sciences ◽

10.22376/ijpbs/lpr.2021.11.6.l116-124 ◽

2021 ◽

Vol 11 (6) ◽

pp. 116-124

Author(s):

Abdulrhman Mustafa Rasheed ◽

Ahmed Fadlalla ◽

Fadelelmoula Tarig ◽

Wael F Asmaa Hegazy Alblowi ◽

Fawaz Alshammari Saitah

Keyword(s):

Rheumatoid Arthritis ◽

Lung Function ◽

Airway Resistance ◽

Lung Function Testing ◽

Mean Values ◽

Pulmonary Manifestations ◽

Medical City ◽

Respiratory Mechanism ◽

Function Testing ◽

Airway Conductance

Pulmonary events in rheumatoid arthritis (RA) reflects the involvement of pleurae, lung interstitium, and airways. Overall, pulmonary manifestations are estimated to cause 10–20% of mortalities in RA. Respiratory system involvement as extra-articular presentations of RA is common among some Saudi patients. This study aims to evaluate specific airway conductance (sGaw), airway resistance (Raw), and specific airway resistance (sRaw), using plethysmography. Comparison for deployed methods is made by forced spirometer as an indicator for obstruction among patients with RA. The study sought to use the methods to enhance lung testing among RA patients. An analytical, hospital-based study was carried out at pulmonary function test laboratory, department of respiratory care King Saud Medical City (KSMC). RA patients were selected, with an age group of 18-75years. The tests for Forced spirometer and plethysmography were carried out to assess and analyze how the respiratory mechanism was impacted by the disease. Data collected was analyzed using Statistical Package for Social Sciences (SPSS), version 21. The obstructive and mixed ventilation patterns constituted 15%; the mean values of Raw and sRaw were significantly higher compared to mean values predicted for participants selected during the study, while sGaw was significantly lower compared to mean values predicted for participants selected. Monitoring of airway resistance parameters using plethysmography can be used as indicators of lung function testing among RA patients.

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