Clonidine: new use of an old medication to reduce stress-related substance use

2016 ◽  
Vol 19 (2) ◽  
pp. e9-e9
Author(s):  
George Woody
2020 ◽  
pp. 1-6
Author(s):  
Jennifer C. Elliott ◽  
Ashley L. Greene ◽  
Ronald G. Thompson ◽  
Nicholas R. Eaton ◽  
Deborah S. Hasin

2017 ◽  
Vol 35 (31_suppl) ◽  
pp. 210-210 ◽  
Author(s):  
Virginia T. LeBaron ◽  
Tareq Fabian Camacho ◽  
Kyle Russell ◽  
Marianne Beare ◽  
Aaron M. Gilson

210 Background: The U.S. is in the throes of two concurrent epidemics: too many people die from opioid-related fatalities, but too many people continue to suffer in pain. In certain regions this dilemma is particularly pronounced. For example, Southwest (SW) Virginia is a rural area with disproportionately high cancer mortality rates and high rates of opioid fatalities. Little is known about how to most effectively and safely manage pain in a region where there exists both a high cancer burden and significant opioid misuse. Purpose: Describe prescription opioid medication (POM) use for patients with cancer in SW Virginia and potential harms. Methods: This is a longitudinal, exploratory, secondary data analysis using the Virginia All Payers Claims Database (APCD), which includes paid medical and pharmacy claims data on 4 million individuals in the Commonwealth of Virginia. Patients with a diagnosis of cancer who lived in far, rural SW Virginia between 2011–2015 were included. Outpatient prescription data were linked to hospitalization admission claims data to explore potential opioid-related harms. Analysis was conducted at the patient, prescription and prescriber level (SAS 9.4, STATA 13.1) to identify predictors of POM use and opioid-related substance use admissions. Results: Within the APCD, POMs represent 7.23% of all medications prescribed for patients with cancer, with hydrocodone- and oxycodone-combinations, oxycodone, fentanyl transdermal patch and morphine sulfate being the most common. Over 50% of patients were prescribed a POM at least once during the study period. Multi-level logistic regressions suggest age, payer source, cancer type, gender, prescriber type and specialty were all significant (p < .001) predictors of being prescribed POMs. Preliminary analyses of hospitalized cancer patients found no association between POM use and opioid-related substance use hospitalization. Conclusions: A clearer view of geographic patterns and predictors of both POM use and potential harms can inform targeted clinical interventions and policy initiatives that achieve a balanced approach to POMs – ensuring access for patients in need, while reducing risk.


2017 ◽  
Vol 26 (5) ◽  
pp. 519-534 ◽  
Author(s):  
Joy D. Scheidell ◽  
Pritika C. Kumar ◽  
Taylor Campion ◽  
Kelly Quinn ◽  
Nisha Beharie ◽  
...  

2021 ◽  
Vol 6 (2) ◽  
pp. 216-221
Author(s):  
Boby Begam ◽  
Kabita Devi

Adolescent starts with early healthy teens and ends up with the many unhealthy issues if not taken care of One of the high risk health issues of adolescence is related to substance use. It is a decade ago worldwide problem where India too has fallen into this viscous cycle. It has not only affected the health of adolescence but has also affected the future of the entire nation. Objectives: The study aimed to find out knowledge and attitude on ill effects of substance use among school going children. Material and Methods: The study adopted cross sectional descriptive design. The study was conducted in three School of Golaghat, Assam for a period of 2 weeks among 265 school going children who were selected using purposive sampling technique after taking the consent. Tool knowledge questionnaire related Substance Use and Attitude scale related Substance Use was used. Results: It was found that 94% of the school going children was having high knowledge level on the ill effects of substance use and their attitude varies towards the substance use. There was no significant association found between knowledge score and selected socio demographic variable. Conclusion: It was found that even after having sufficient knowledge and negative attitude towards the substance use, many adolescent are trapped in this phenomena. It may be because of lack of assertiveness and weaken coping ability of the adolescence. Keywords: Knowledge, Attitude, Substance use, School Going Children.


2018 ◽  
Vol 72 (7) ◽  
pp. 582-588 ◽  
Author(s):  
Malin Henriksson ◽  
Jenny Nyberg ◽  
Linus Schiöler ◽  
Gunnel Hensing ◽  
Georg H Kuhn ◽  
...  

BackgroundWhile risk of premature death is most pronounced among persons with severe mental illness, also milder conditions are associated with increased all-cause mortality. We examined non-psychotic mental (NPM) disorders and specific causes of natural death in a cohort of late adolescent men followed for up to 46 years.MethodsProspective cohort study of Swedish males (n=1 784 626) who took part in structured conscription interviews 1968–2005. 74 525 men were diagnosed with NPM disorders at or prior to conscription. Median follow-up time was 26 years. HRs for cause-specific mortality were calculated using Cox proportional hazards models.ResultsRisks in fully adjusted models were particularly elevated for death by infectious diseases (depressive and neurotic/adjustment disorders (HR 2.07; 95% CI 1.60 to 2.67), personality disorders (HR 2.90; 95% CI 1.96 to 4.28) and alcohol-related and other substance use disorders (HR 9.02; 95% CI 6.63 to 12.27)) as well as by gastrointestinal causes (depressive and neurotic/adjustment disorders (HR 1.64; 95% CI 1.42 to 1.89), personality disorders (HR 2.77; 95% CI 2.27 to 3.38) and alcohol-related/substance use disorders (HR 4.41; 95% CI 3.59 to 5.42)).ConclusionYoung men diagnosed with NPM disorders had a long-term increased mortality risk, in particular due to infectious and gastrointestinal conditions. These findings highlight the importance of early preventive actions for adolescents with mental illness.


2020 ◽  
Vol 10 (12) ◽  
pp. 1007
Author(s):  
Morgan Driver ◽  
Sally Kuo ◽  
Danielle Dick ◽  

An exponential growing number of individuals are accessing genetic risk information via direct to consumer companies. Alcohol dependence is the third most accessed genetic risk score on a publicly available direct to consumer website. Better understanding of the degree to which individuals are interested in receiving personalized genetic feedback, the factors that relate to interest, and genetic knowledge will be critical to lay the foundation for precision medicine initiatives, especially for substance use and psychiatric outcomes, where less is known. To assess interest in receiving genetic feedback for alcohol use disorder (AUD) and understanding of genetic concepts related to psychiatric conditions, we conducted a survey with participants recruited from a registry that enrolled incoming cohorts of freshmen at an urban public university; 205 participants (76.5% female; 58.9% self-reported as White; Mage = 24.48 years) completed the survey. Results indicated that participants are highly interested in receiving genetic feedback for AUD (79.0%) but there is a lack of understanding of complex genetic concepts in a sizable proportion of the sample (25.4%). Additional research is needed to assess how to address this lack of knowledge before genetic feedback for AUD can be returned in a way that benefits the individual.


2020 ◽  
Vol 11 (1) ◽  
pp. 29-35
Author(s):  
Amy Witkoski Stimpfel ◽  
Eva Liang ◽  
Lloyd A. Goldsamt

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