scholarly journals Prospective validation of Canadian TIA Score and comparison with ABCD2 and ABCD2i for subsequent stroke risk after transient ischaemic attack: multicentre prospective cohort study

BMJ ◽  
2021 ◽  
pp. n453
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Transient Ischaemic Attack ◽  
Prospective Cohort ◽  
Stroke Risk ◽  
Ischaemic Attack

scholarly journals Small cortical grey matter lesions show no persistent infarction in transient ischaemic attack? A prospective cohort study

BMJ Open ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. e018160 ◽  
Author(s):  
Inger Havsteen ◽  
Christian Ovesen ◽  
Lasse Willer ◽  
Janus Damm Nybing ◽  
Karen Ægidius ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Transient Ischaemic Attack ◽  
Prospective Cohort ◽  
Grey Matter ◽  
Cortical Grey Matter ◽  
Ischaemic Attack

scholarly journals Recording a diagnosis of stroke, transient ischaemic attack or myocardial infarction in primary healthcare and the association with dispensation of secondary preventive medication: a registry-based prospective cohort study

BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e015723 ◽  
Author(s):  
Cecilia Dahlgren ◽  
Lukas Geary ◽  
Jan Hasselström ◽  
Clas Rehnberg ◽  
Karin Schenck-Gustafsson ◽  
...  
Keyword(s):  
Primary Care ◽  
Acute Coronary Syndrome ◽  
Cohort Study ◽  
Hospital Discharge ◽  
Prospective Cohort Study ◽  
Transient Ischaemic Attack ◽  
Prospective Cohort ◽  
Coronary Syndrome ◽  
Ischaemic Attack ◽  
Recorded Diagnosis

ObjectivesThe aim of this study was to explore whether recording in primary care of a previously recorded hospital diagnosis was associated with increased patient utilisation of recommended medications.DesignRegistry-based prospective cohort study.Setting and participants19 072 patients with a hospital discharge diagnosis of transient ischaemic attack (TIA), stroke or acute coronary syndrome from hospitals in Stockholm County 2010–2013 were included in the study.Main outcome measureThe outcome of the study was medication dispensation as a marker of adherence to recommended medications. Adherence was defined as having had at least two filled prescriptions in the third year following hospital discharge.ResultsRecording a diagnosis was associated with higher utilisation of all recommended medications with the exception of antihypertensives in patients with TIA. The differences between the groups with and without a recorded diagnosis remained after adjusting for age, sex, index year and visits to private practitioners. Dispensation of antithrombotics was high overall, 80%–90% in patients without a recorded diagnosis and 90%–94% for those with a diagnosis. Women with recorded ischaemic stroke/TIA/acute coronary syndrome were dispensed more statins (56%–71%) than those with no recorded diagnosis (46%–59%). Similarly, 68%–83% of men with a recorded diagnosis were dispensed statins (57%–77% in men with no recorded diagnosis). The rate of diagnosis recording spanned from 15% to 47% and was especially low in TIA (men 15%, women 16%).ConclusionRecording a diagnosis of TIA/stroke or acute coronary syndrome in primary care was found to be associated with higher dispensation of recommended secondary preventive medications. Further study is necessary in order to determine the mechanisms underlying our results and to establish the utility of our findings.

scholarly journals Prospective validation of Canadian TIA Score and comparison with ABCD2 and ABCD2i for subsequent stroke risk after transient ischaemic attack: multicentre prospective cohort study

BMJ ◽  
2021 ◽  
pp. n49
Author(s):  
Jeffrey J Perry ◽  
Marco L A Sivilotti ◽  
Marcel Émond ◽  
Ian G Stiell ◽  
Grant Stotts ◽  
...  
Keyword(s):  
Emergency Department ◽  
Cohort Study ◽  
Carotid Artery ◽  
Confidence Interval ◽  
Carotid Endarterectomy ◽  
Likelihood Ratio ◽  
Transient Ischaemic Attack ◽  
Carotid Artery Stenting ◽  
Stroke Risk ◽  
Ischaemic Attack

Abstract Objective To validate the previously derived Canadian TIA Score to stratify subsequent stroke risk in a new cohort of emergency department patients with transient ischaemic attack. Design Prospective cohort study. Setting 13 Canadian emergency departments over five years. Participants 7607 consecutively enrolled adult patients attending the emergency department with transient ischaemic attack or minor stroke. Main outcome measures The primary outcome was subsequent stroke or carotid endarterectomy/carotid artery stenting within seven days. The secondary outcome was subsequent stroke within seven days (with or without carotid endarterectomy/carotid artery stenting). Telephone follow-up used the validated Questionnaire for Verifying Stroke Free Status at seven and 90 days. All outcomes were adjudicated by panels of three stroke experts, blinded to the index emergency department visit. Results Of the 7607 patients, 108 (1.4%) had a subsequent stroke within seven days, 83 (1.1%) had carotid endarterectomy/carotid artery stenting within seven days, and nine had both. The Canadian TIA Score stratified the risk of stroke, carotid endarterectomy/carotid artery stenting, or both within seven days as low (risk ≤0.5%; interval likelihood ratio 0.20, 95% confidence interval 0.09 to 0.44), medium (risk 2.3%; interval likelihood ratio 0.94, 0.85 to 1.04), and high (risk 5.9% interval likelihood ratio 2.56, 2.02 to 3.25) more accurately (area under the curve 0.70, 95% confidence interval 0.66 to 0.73) than did the ABCD2 (0.60, 0.55 to 0.64) or ABCD2i (0.64, 0.59 to 0.68). Results were similar for subsequent stroke regardless of carotid endarterectomy/carotid artery stenting within seven days. Conclusion The Canadian TIA Score stratifies patients’ seven day risk for stroke, with or without carotid endarterectomy/carotid artery stenting, and is now ready for clinical use. Incorporating this validated risk estimate into management plans should improve early decision making at the index emergency visit regarding benefits of hospital admission, timing of investigations, and prioritisation of specialist referral.

scholarly journals Triglycerides and Stroke Risk Prediction: Lessons from a Prospective Cohort Study in German Primary Care Patients

2010 ◽  
Vol 1 ◽  
Author(s):  
Martin Ebinger ◽  
Caroline Sievers ◽  
Jens Klotsche ◽  
Harald J. Schneider ◽  
Christopher O. Leonards ◽  
...  
Keyword(s):  
Primary Care ◽  
Cohort Study ◽  
Risk Prediction ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Stroke Risk ◽  
Primary Care Patients

scholarly journals Validation of the RRE-90 Scale to Predict Stroke Risk after Transient Symptoms with Infarction: A Prospective Cohort Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0137425 ◽  
Author(s):  
Bo Song ◽  
Lulu Pei ◽  
Hui Fang ◽  
Lu Zhao ◽  
Yuan Gao ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Stroke Risk

scholarly journals Education, sex and risk of stroke: a prospective cohort study in New South Wales, Australia

BMJ Open ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. e024070 ◽  
Author(s):  
Caroline A Jackson ◽  
Cathie L M Sudlow ◽  
Gita D Mishra
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Stroke Risk ◽  
New South ◽  
New South Wales ◽  
Education Level ◽  
Men And Women ◽  
South Wales ◽  
Low Education

ObjectiveTo determine whether the association between highest educational attainment and stroke differed by sex and age; and whether potential mediators of observed associations differ by sex.DesignProspective cohort study.SettingPopulation based, New South Wales, Australia.Participants253 657 stroke-free participants from the New South Wales 45 and Up Study.Outcome measuresFirst-ever stroke events, identified through linkage to hospital and mortality records.ResultsDuring mean follow-up of 4.7 years, 2031 and 1528 strokes occurred among men and women, respectively. Age-standardised stroke rate was inversely associated with education level, with the absolute risk difference between the lowest and highest education group greater among women than men. In relative terms, stroke risk was slightly more pronounced in women than men when comparing low versus high education (age-adjusted HRs: 1.41, 95% CI 1.16 to 1.71 and 1.25, 95% CI 1.07 to 1.46, respectively), but there was no clear evidence of statistical interaction. This association persisted into older age, but attenuated. Much of the increased stroke risk was explained by modifiable lifestyle factors, in both men and women.ConclusionLow education is associated with increased stroke risk in men and women, and may be marginally steeper in women than men. This disadvantage attenuates but persists into older age, particularly for women. Modifiable risk factors account for much of the excess risk from low education level. Public health policy and governmental decision-making should reflect the importance of education, for both men and women, for positive health throughout the life course.

Organizational Justice and Health of Employees: Prospective Cohort Study.

2013 ◽  
Author(s):  
Mika Kivimaki ◽  
Marko Elovainio ◽  
Jussi Vahtera ◽  
Marianna Virtanen ◽  
Jane E. Ferrie
Keyword(s):  
Cohort Study ◽  
Organizational Justice ◽  
Prospective Cohort Study ◽  
Prospective Cohort
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