scholarly journals Living network meta-analysis compared with pairwise meta-analysis in comparative effectiveness research: empirical study

BMJ ◽  
2018 ◽  
pp. k585 ◽  
Author(s):  
Adriani Nikolakopoulou ◽  
Dimitris Mavridis ◽  
Toshi A Furukawa ◽  
Andrea Cipriani ◽  
Andrea C Tricco ◽  
...  
Keyword(s):  
Empirical Study ◽  
Comparative Effectiveness Research ◽  
Comparative Effectiveness ◽  
Meta Analysis ◽  
Effectiveness Research

scholarly journals Comparative Effectiveness Research: Using Systematic Reviews and Meta-Analyses to Synthesize Empirical Evidence

2011 ◽  
Vol 25 (3) ◽  
pp. 191-209 ◽  
Author(s):  
Maria C. Katapodi ◽  
Laurel L. Northouse
Keyword(s):  
Systematic Reviews ◽  
Comparative Effectiveness Research ◽  
Comparative Effectiveness ◽  
Meta Analysis ◽  
Research Question ◽  
Alternative Methods ◽  
Evidence Based ◽  
Effectiveness Research ◽  
Meta Analyses ◽  
Research Studies

The increased demand for evidence-based health care practices calls for comparative effectiveness research (CER), namely the generation and synthesis of research evidence to compare the benefits and harms of alternative methods of care. A significant contribution of CER is the systematic identification and synthesis of available research studies on a specific topic. The purpose of this article is to provide an overview of methodological issues pertaining to systematic reviews and meta-analyses to be used by investigators with the purpose of conducting CER. A systematic review or meta-analysis is guided by a research protocol, which includes (a) the research question, (b) inclusion and exclusion criteria with respect to the target population and studies, © guidelines for obtaining relevant studies, (d) methods for data extraction and coding, (e) methods for data synthesis, and (f ) guidelines for reporting results and assessing for bias. This article presents an algorithm for generating evidence-based knowledge by systematically identifying, retrieving, and synthesizing large bodies of research studies. Recommendations for evaluating the strength of evidence, interpreting findings, and discussing clinical applicability are offered.

67 ADVANCING COMPARATIVE EFFECTIVENESS RESEARCH THROUGH NETWORK META-ANALYSIS: INTRAVESICAL THERAPY IN BLADDER CANCER

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Mia Djulbegovic ◽  
Benjamin Djulbegovic ◽  
Mina Zarei ◽  
Scott Gilbert ◽  
Molly M. Neuberger ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Comparative Effectiveness Research ◽  
Comparative Effectiveness ◽  
Meta Analysis ◽  
Intravesical Therapy ◽  
Effectiveness Research
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