scholarly journals Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation

BMJ ◽  
2013 ◽  
Vol 347 (aug06 2) ◽  
pp. f4752-f4752 ◽  
Author(s):  
X. Qi ◽  
Y.-H. Qian ◽  
C.-J. Bao ◽  
X.-L. Guo ◽  
L.-B. Cui ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Eastern China ◽  
H7n9 Virus ◽  
Epidemiological Investigation

Person-to-Person Transmission of Avian Influenza A (H7N9) Among Family Members in Eastern China, 2016

2020 ◽  
pp. 1-6
Author(s):  
Chao Shi ◽  
Ping Shi ◽  
Xu Yang ◽  
Jing Bao ◽  
Yanhua Qian ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Early Stage ◽  
Close Contact ◽  
Eastern China ◽  
Family Members ◽  
Index Patient ◽  
H7n9 Virus ◽  
Viral Shedding ◽  
Live Poultry

ABSTRACT Objective: Human infections with avian influenza A (H7N9) virus are associated with exposure to poultry and live poultry markets, but the evidence of person-to-person transmission remains limited. This study reports a suspected person-to-person transmission of H7N9 virus, and explores what factors influenced this transmission. Methods: We interviewed 2 patients with H7N9 infection and their family members as well as health-care workers. Samples from the patients and environments were tested by real-time reverse transcription-polymerase chain reaction. Results: The index patient became ill 5 to 6 days after his last exposure to the poultry bought in the market of Weimiao town. The second patient, the sister of the index patient, who had sustained intensive and unprotected close contact with the index patient, had no exposure to poultry. This study documents that the H7N9 virus was transmitted directly from the index patient to his sister. Conclusions: Our findings suggest that person-to-person transmission may be associated with sustained close contact with the patient during his onset of early stage, when the H7N9 viral shedding increases sharply.

scholarly journals Nosocomial transmission of avian influenza A (H7N9) virus in China: epidemiological investigation

BMJ ◽  
2015 ◽  
Vol 351 (nov19 10) ◽  
pp. h5765-h5765 ◽  
Author(s):  
C.-F. Fang ◽  
M.-J. Ma ◽  
B.-D. Zhan ◽  
S.-M. Lai ◽  
Y. Hu ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Nosocomial Transmission ◽  
H7n9 Virus ◽  
Epidemiological Investigation

scholarly journals Biological characterisation of the emerged highly pathogenic avian influenza (HPAI) A(H7N9) viruses in humans, in mainland China, 2016 to 2017

2017 ◽  
Vol 22 (19) ◽  
Author(s):  
Wenfei Zhu ◽  
Jianfang Zhou ◽  
Zi Li ◽  
Lei Yang ◽  
Xiyan Li ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Mainland China ◽  
H7n9 Virus ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza ◽  
Binding Preference ◽  
Severe Infections ◽  
Epidemic Wave

With no or low virulence in poultry, avian influenza A(H7N9) virus has caused severe infections in humans. In the current fifth epidemic wave, a highly pathogenic avian influenza (HPAI) H7N9 virus emerged. The insertion of four amino acids (KRTA) at the haemagglutinin (HA) cleavage site enabled trypsin-independent infectivity of this virus. Although maintaining dual receptor-binding preference, its HA antigenicity was distinct from low-pathogenic avian influenza A(H7N9). The neuraminidase substitution R292K conferred a multidrug resistance phenotype.

scholarly journals Genetically Divergent Highly Pathogenic Avian Influenza A(H5N8) Viruses in Wild Birds, Eastern China

2021 ◽  
Vol 27 (11) ◽  
pp. 2940-2943
Author(s):  
Guimei He ◽  
Le Ming ◽  
Xiang Li ◽  
Yuhe Song ◽  
Ling Tang ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Eastern China ◽  
Wild Birds ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza
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