Does the evidence support the use of mild hypothermia after cardiac arrest? Yes

BMJ ◽  
2011 ◽  
Vol 343 (sep22 2) ◽  
pp. d5830-d5830 ◽  
Author(s):  
J. P. Nolan ◽  
J. Soar
Keyword(s):  
Cardiac Arrest ◽  
Mild Hypothermia

scholarly journals Mild hypothermia after cardiac arrest in dogs does not affect postarrest multifocal cerebral hypoperfusion.

Stroke ◽  
1993 ◽  
Vol 24 (10) ◽  
pp. 1590-1597 ◽  
Author(s):  
K Oku ◽  
F Sterz ◽  
P Safar ◽  
D Johnson ◽  
W Obrist ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Mild Hypothermia ◽  
Cerebral Hypoperfusion

scholarly journals Our experiences with therapeutic hypothermia

2007 ◽  
Vol 60 (9-10) ◽  
pp. 431-435 ◽  
Author(s):  
Milovan Petrovic ◽  
Ilija Srdanovic ◽  
Gordana Panic ◽  
Tibor Canji ◽  
Tihomir Miljevic
Keyword(s):  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Neurological Outcome ◽  
Mild Hypothermia ◽  
Acute Myocarditis ◽  
Neuroprotective Effect ◽  
Sudden Cardiac Arrest ◽  
Neurological Recovery ◽  
Global Cerebral Ischemia ◽  
Resuscitation Guidelines

Introduction. The single most important clinically relevant cause of global cerebral ischemia is cardiac arrest. The estimated rate of sudden cardiac arrest is between 40 and 130 cases per 100.000 people per year. Almost 80% of patients initially resuscitated from cardiac arrest remain comatose for more than one hour. One year after cardiac arrest only 10-30% of these patients survive with good neurological outcome. The ability to survive anoxic no-flow states is dramatically increased with protective and preservative hypothermia. The results of clinical studies show a marked neuroprotective effect of mild hypothermia in resuscitation. Material and Methods. In our clinic, 12 patients were treated with therapeutic hypothermia. A combination of intravascular and external method of cooling was used according to the ILCOR (International Liaison Committee on Resuscitation) guidelines. The target temperature was 33oC, while the duration of cooling was 24 hours. After that, passive rewarming was allowed. All patients also received other necessary therapy. Results. Six patients (50%) had a complete neurological recovery. Two patients (16.6%) had partial neurological recovery. Four patients (33.3%) remained comatose. Five patients (41.66%) survived, while 7 (58.33%) patients died. The main cause of cardiac arrest was acute myocardial infarction (91.6%). One patient had acute myocarditis. Conclusion. Mild resuscitative hypothermia after cardiac arrest improves neurological outcome and reduces mortality in comatose survivors. .

Induced Moderate Hypothermia After Cardiac Arrest

2009 ◽  
Vol 20 (4) ◽  
pp. 343-355
Author(s):  
Staci McKean
Keyword(s):  
Cardiac Arrest ◽  
Best Practice ◽  
Mild Hypothermia ◽  
Head Injuries ◽  
Heart Association ◽  
Spontaneous Circulation ◽  
Moderate Hypothermia ◽  
Induced Hypothermia ◽  
Nursing Management ◽  
Hospital Cardiac Arrest

The use of induced hypothermia has been considered for treatment of head injuries since the 1900s. However, it was not until 2 landmark studies were published in 2002 that induced hypothermia was considered best practice for patients after cardiac arrest. In 2005, the American Heart Association included recommendations in the postresuscitation support guidelines recommending consideration of mild hypothermia for unconscious adult patients with return of spontaneous circulation following out-of-hospital cardiac arrest due to ventricular fibrillation. This article provides an overview on the history and supportive research for inducing mild hypothermia after cardiac arrest, the pathophysiology associated with cerebral ischemia occurring with hypothermia, nursing management for this patient population, and the development of a protocol for induced hypothermia after cardiac arrest.

Mild hypothermia cardiopulmonary resuscitation improves outcome after prolonged cardiac arrest in dogs

1991 ◽  
Vol 19 (3) ◽  
pp. 379-389 ◽  
Author(s):  
FRITZ STERZ ◽  
PETER SAFAR ◽  
SAMUEL TISHERMAN ◽  
ANN RADOVSKY ◽  
KAZUTOSHI KUBOYAMA ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Cardiopulmonary Resuscitation ◽  
Mild Hypothermia

MILD HYPOTHERMIA (Hth) PLUS CEREBRAL BLOOD FLOW (CBF) PROMOTION, BUT NOT DRUGS, GIVE COMPLETE FUNCTIONAL RECOVERY AFTER 11 MIN CARDIAC ARREST (CA) IN DOGS

1995 ◽  
Vol 23 (Supplement) ◽  
pp. A179 ◽  
Author(s):  
Feng Xiao ◽  
Peter Safar ◽  
Ann Radovsky ◽  
Koichi Tanigawa ◽  
Yuanfan Wang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiac Arrest ◽  
Cerebral Blood Flow ◽  
Functional Recovery ◽  
Mild Hypothermia

Predictors of poor neurologic outcome after induced mild hypothermia following cardiac arrest

Neurology ◽  
2008 ◽  
Vol 71 (19) ◽  
pp. 1535-1537 ◽  
Author(s):  
E. Al Thenayan ◽  
M. Savard ◽  
M. Sharpe ◽  
L. Norton ◽  
B. Young
Keyword(s):  
Cardiac Arrest ◽  
Mild Hypothermia ◽  
Neurologic Outcome

Hemostasis in cardiac arrest patients treated with mild hypothermia initiated by cold fluids

Resuscitation ◽  
2009 ◽  
Vol 80 (7) ◽  
pp. 762-765 ◽  
Author(s):  
Alexander O. Spiel ◽  
Andreas Kliegel ◽  
Andreas Janata ◽  
Thomas Uray ◽  
Florian B. Mayr ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Mild Hypothermia
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