scholarly journals Reappraisal of the ratio of disc to macula/disc diameter in optic nerve hypoplasia.

1991 ◽  
Vol 75 (9) ◽  
pp. 538-541 ◽  
Author(s):  
S M Zeki ◽  
J Dudgeon ◽  
G N Dutton
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Hypoplasia ◽  
Disc Diameter

Unilateral optic nerve hypoplasia in a case of septo-optic dysplasia

2021 ◽  
Author(s):  
R. El Hachimi ◽  
S. Benchekroun ◽  
R. El Hadiri ◽  
L.O. Cherkaoui
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Hypoplasia

scholarly journals Endocrine Dysfunction in Children with Zika-Related Microcephaly Who Were Born during the 2015 Epidemic in the State of Pernambuco, Brazil

Viruses ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 1
Author(s):  
Andréia Veras Gonçalves ◽  
Demócrito de B. Miranda-Filho ◽  
Líbia Cristina Rocha Vilela ◽  
Regina Coeli Ferreira Ramos ◽  
Thalia V. B. de Araújo ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Viral Infections ◽  
Case Series ◽  
Optic Nerve Hypoplasia ◽  
Endocrine Dysfunction ◽  
Careful Monitoring ◽  
Early Puberty ◽  
Growth Impairment ◽  
Appropriate Treatment ◽  
The Brain

Congenital viral infections and the occurrence of septo-optic dysplasia, which is a combination of optic nerve hypoplasia, abnormal formation of structures along the midline of the brain, and pituitary hypofunction, support the biological plausibility of endocrine dysfunction in Zika-related microcephaly. In this case series we ascertained the presence and describe endocrine dysfunction in 30 children with severe Zika-related microcephaly from the MERG Pediatric Cohort, referred for endocrinological evaluation between February and August 2019. Of the 30 children, 97% had severe microcephaly. The average age at the endocrinological consultation was 41 months and 53% were female. The most frequently observed endocrine dysfunctions comprised short stature, hypothyroidism, obesity and variants early puberty. These dysfunctions occurred alone 57% or in combination 43%. We found optic nerve hypoplasia (6/21) and corpus callosum hypoplasia (20/21). Seizure crises were reported in 86% of the children. The most common—and clinically important—endocrine dysfunctions were pubertal dysfunctions, thyroid disease, growth impairment, and obesity. These dysfunctions require careful monitoring and signal the need for endocrinological evaluation in children with Zika-related microcephaly, in order to make early diagnoses and implement appropriate treatment when necessary.

Distinctive histopathologic features of canine optic nerve hypoplasia and aplasia: a retrospective review of 13 cases

2008 ◽  
Vol 11 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Enry Garcia da Silva ◽  
Richard Dubielzig ◽  
Mitzi K. Zarfoss ◽  
Armien Anibal
Keyword(s):  
Optic Nerve ◽  
Retrospective Review ◽  
Optic Nerve Hypoplasia ◽  
Histopathologic Features
Sign in / Sign up

Export Citation Format

Share Document