scholarly journals Use of contrast sensitivity measurement in the detection of subclinical ethambutol toxic optic neuropathy.

1987 ◽  
Vol 71 (3) ◽  
pp. 192-196 ◽  
Author(s):  
J F Salmon ◽  
T R Carmichael ◽  
N H Welsh
Keyword(s):  
Contrast Sensitivity ◽  
Optic Neuropathy ◽  
Sensitivity Measurement ◽  
Toxic Optic Neuropathy

A Case of Presumed Bonsai-induced Severe Toxic Optic Neuropathy

2021 ◽  
pp. 1-3
Author(s):  
Erdogan Yasar ◽  
Hatice Suhan Tomac ◽  
Ugur Gurlevik
Keyword(s):  
Optic Neuropathy ◽  
Toxic Optic Neuropathy

Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis

2018 ◽  
Vol 30 (1) ◽  
pp. 139-140 ◽  
Author(s):  
Proteesh Rana ◽  
Vandana Roy ◽  
Jamshed Ahmad
Keyword(s):  
Pulmonary Tuberculosis ◽  
Optic Neuritis ◽  
Male Patient ◽  
Optic Neuropathy ◽  
High Dose ◽  
Drug Resistant ◽  
Drug Reactions ◽  
Drug Induced ◽  
Toxic Optic Neuropathy ◽  
Extensively Drug Resistant

Abstract We report a 26-year-old male patient diagnosed with extensively drug-resistant pulmonary tuberculosis presenting with reversible bilateral toxic optic neuropathy induced by the use of linezolid along with high-dose isoniazid. The case emphasizes the importance of recognizing toxic optic neuritis in patients on antitubercular therapy. Prompt recognition and treatment of such adverse drug reactions will reduce the associated morbidity.

scholarly journals Tacrolimus-induced bilateral optic neuropathy: A case report

2021 ◽  
pp. 4-4
Author(s):  
Lepsa Zoric ◽  
Aleksandra Ilic ◽  
Emina Colak ◽  
Milos Mirkovic ◽  
Jelica Pantelic ◽  
...  
Keyword(s):  
Case Report ◽  
Adverse Effects ◽  
Optic Neuropathy ◽  
Vision Loss ◽  
White Male ◽  
Immunosuppressive Drug ◽  
Organ Rejection ◽  
Toxic Optic Neuropathy ◽  
Tacrolimus Therapy ◽  
Male Patients

Intrduction. Tacrolimus (fujimycin or FK506) is a potent immunosuppressive drug with growing usage. It is usually used in prevention of transplanted organ rejection. Its use is highly valuable, but like other immunosupressants, it has adverse effects. One of them is optic neuropathy. Case report. A 47-year-old white male patients who had received tacrolimus therapy for nine years, after kidney transplantation, developed a subacute, painless vision loss on both eyes. He was thoroughly examined on different possible optic neuropathies and other causes of vision loss. After exclusion of other possible causes, the diagnosis of toxic optic neuropathy was established. His therapy was converted to cyclosporine, by his nephrologist, but his vision had improved only slightly. Conclusion. Toxic optic neuropathies are presented in everyday ophthalmological practice, but they are underestimated. Diagnosis can be demanding, especially when it comes to drugs and substances whose possible toxic effect on the optic nerve is not widely known. Unlike other adverse effects of tacrolimus therapy on nervous system, optic neuropathy can causes great and permanent functional impairment.

Toluene Related Toxic Optic Neuropathy

2009 ◽  
Vol 33 (5) ◽  
pp. 248-252
Author(s):  
Fatih Gundogan ◽  
Ebru Gorgun ◽  
Oguzhan Oz ◽  
Fatih Mutlu ◽  
Gungor Sobaci ◽  
...  
Keyword(s):  
Optic Neuropathy ◽  
Toxic Optic Neuropathy

Toluene Related Toxic Optic Neuropathy

2009 ◽  
Vol 33 (5) ◽  
pp. 248-252
Author(s):  
Fatih C. Gundogan ◽  
Ebru Gorgun ◽  
Oguzhan Oz ◽  
Fatih M. Mutlu ◽  
Gungor Sobaci ◽  
...  
Keyword(s):  
Optic Neuropathy ◽  
Toxic Optic Neuropathy

Contrast Sensitivity and Visual-Field Thresholds in Patients with Thyroid Optic Neuropathy

Perception ◽  
1997 ◽  
Vol 26 (1_suppl) ◽  
pp. 194-194
Author(s):  
J Jankauskiene ◽  
R Lukauskiene ◽  
B Mickiene
Keyword(s):  
Visual Acuity ◽  
Visual Field ◽  
Contrast Sensitivity ◽  
Optic Neuropathy ◽  
Control Group ◽  
Ophthalmological Examination ◽  
Threshold Test ◽  
Spatial Frequencies ◽  
Snellen Visual Acuity ◽  
The Mean

Thyroid optic neuropathy is one of the most troubling complications of endocrine ophthalmopathies. It is related to the degree of extraocular muscle swelling in the apex of the orbit. The purpose of this study was to investigate contrast sensitivity and visual-field thresholds in patients with thyroid optic neuropathy. We examined twenty-two patients aged 29 – 63 years (mean 45.3 years). The control group consisted of fifteen healthy persons of similar age. Contrast sensitivity was measured by means of Volkov's charts (sinusoidal gratings) at eight spatial frequencies from 17.5 to 0.46 cycles deg−1. The visual field was investigated with a static automatic perimeter (Allgan Humphrey Field Analyzer) by means of the central 30-2 threshold test. All patients underwent a complete ophthalmological examination including best corrected Snellen visual acuity, fundus copy, and proptosis measurement with the Hertel exophthalmometer. The mean proptosis of patients was 19.4 mm. Fifteen of the patients had decreased visual acuity. Contrast sensitivity at low spatial frequencies was significantly reduced in the patients. It was established that a reduction of visual-field threshold accompanies the decrease of visual acuity. Our results show that contrast sensitivity and visual-field threshold testing are very sensitive at detecting early optic neuropathy and may be a useful means of following patients after treatment.

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