Ring melanoma of the iris and ciliary body.

W Omulecki; M Pruszczynski; J Borowski

doi:10.1136/bjo.69.7.514

Diffuse Malignant Ring Melanoma of the Iris and Ciliary Body

Ophthalmologica ◽

10.1159/000308830 ◽

1979 ◽

Vol 178 (4) ◽

pp. 235-238 ◽

Cited By ~ 4

Author(s):

Olga Litričin

Keyword(s):

Ciliary Body ◽

Ring Melanoma

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Isolated Ocular Sarcoidosis Mimicking Ring Melanoma

Ocular Oncology and Pathology ◽

10.1159/000504784 ◽

2019 ◽

Vol 6 (3) ◽

pp. 180-183

Author(s):

Carsten Faber ◽

Rasmus Ejstrup ◽

Karine Madsen ◽

Steffen Heegaard ◽

David Scheie ◽

...

Keyword(s):

Ciliary Body ◽

Frozen Section ◽

Granulomatous Inflammation ◽

Ultrasound Biomicroscopy ◽

Anterior Chamber Angle ◽

Ocular Sarcoidosis ◽

Sarcoid Granuloma ◽

Subtenon Injection ◽

Ring Melanoma ◽

Work Up

We report the case of a 25-year-old female, who presented with a large, pale tumor of her ciliary body that extended to >180° of the anterior chamber angle. All preoperative examinations including ultrasound biomicroscopy, scleral transillumination, and MRI indicated melanoma. A thorough systemic work-up was negative. A diagnosis of ring melanoma was suspected, and the patient was scheduled for enucleation. However, perioperative frozen section indicated granulomatous inflammation. The enucleation was cancelled, and a subtenon injection of triamcinolone was administered, which resulted in the disappearance of the tumor. Together, the findings meet the criteria for the diagnosis of isolated ocular sarcoidosis. This case demonstrates that a sarcoid granuloma can mimic all clinical features of a ring melanoma. Therefore, a biopsy should be done before destructive surgery is carried out.

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Ring melanoma of the ciliary body: clinical and ultrasound biomicroscopic characteristics

Canadian Journal of Ophthalmology ◽

10.3129/i08-025 ◽

2008 ◽

Vol 43 (2) ◽

pp. 229-233 ◽

Cited By ~ 10

Author(s):

Luz M. Vásquez ◽

Charles J. Pavlin ◽

Hugh McGowan ◽

E. Rand Simpson

Keyword(s):

Ciliary Body ◽

Ring Melanoma

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Corrigendum: Ring melanoma of the ciliary body: clinical and ultrasound biomicroscopic characteristics

Canadian Journal of Ophthalmology ◽

10.1139/i08-050 ◽

2008 ◽

Vol 43 (3) ◽

pp. 378-378

Author(s):

Luz M. Vásquez ◽

Charles J. Pavlin ◽

Hugh McGowan ◽

Yeni Yücel ◽

E. Rand Simpson

Keyword(s):

Ciliary Body ◽

Ring Melanoma

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Corrigendum: Ring melanoma of the ciliary body: clinical and ultrasound biomicroscopic characteristics

Canadian Journal of Ophthalmology ◽

10.1016/s0008-4182(08)80132-9 ◽

2008 ◽

Vol 43 (3) ◽

pp. 378

Author(s):

Luz M. Vásquez

Keyword(s):

Ciliary Body ◽

Ring Melanoma

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Malignant Melanoma of the Iris a 25-Year Analysis of Danish Cases

European Journal of Ophthalmology ◽

10.1177/112067219300300402 ◽

1993 ◽

Vol 3 (4) ◽

pp. 181-188 ◽

Cited By ~ 27

Author(s):

O.A. Jensen

Keyword(s):

Malignant Melanoma ◽

Cell Morphology ◽

Ciliary Body ◽

Incomplete Resection ◽

Average Population ◽

Ring Melanoma ◽

Chamber Angle

This study examined malignant melanoma of the iris in Denmark over a 25-year period on the basis of the files of the Eye Pathology Institute. From 1961 to 1985 a total of 80 cases were found (41 males, 39 females; median age 53 years, range 8 - 83). This means an average of 3.2 cases/year with an average population of 4.9 million. In contrast to malignant melanoma of the choroid, an increase was observed. The reason is not known, although exposure to actinic rays may be a factor. More than a third of cases were close to the pupil, a little less than a third invaded the chamber angle/ciliary body. Ten cases were ring melanomas. Half of the tumours were spindle-celled, a quarter mixed and a few epithelioid or naevoid in cell morphology. Iridectomy was performed in 28 cases, primary enucleation in 27 and secondary enucleation in ten. Iridocyclectomy was performed in 15 cases. All patients could be traced. At the date of follow-up (Dec. 1, 1991) eight had died with metastases; four of these were patients with ring melanoma and four with tumours invading the ciliary body. After iridocyclectomy, only one metastatic death was recorded –- a case of incomplete resection. The grave prognosis of a ring melanoma is highlighted.

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