scholarly journals Haematological factors associated with proliferative retinopathy in sickle cell-haemoglobin C disease.

1981 ◽  
Vol 65 (10) ◽  
pp. 712-717 ◽  
Author(s):  
R J Hayes ◽  
P I Condon ◽  
G R Serjeant
Keyword(s):  
Sickle Cell ◽  
Proliferative Retinopathy ◽  
Factors Associated ◽  
Haemoglobin C

scholarly journals Blood rheology and proliferative retinopathy in sickle cell-haemoglobin C disease.

1984 ◽  
Vol 68 (5) ◽  
pp. 325-328 ◽  
Author(s):  
B E Serjeant ◽  
K P Mason ◽  
P I Condon ◽  
R J Hayes ◽  
M W Kenny ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Blood Rheology ◽  
Proliferative Retinopathy ◽  
Haemoglobin C

scholarly journals Laser photocoagulation for proliferative retinopathy in sickle haemoglobin C disease

Eye ◽  
1993 ◽  
Vol 7 (5) ◽  
pp. 703-706 ◽  
Author(s):  
Peter D Fox ◽  
Kyra Minninger ◽  
Mark L Forshaw ◽  
S J Rupert Vessey ◽  
Joanne S Morris ◽  
...  
Keyword(s):  
Laser Photocoagulation ◽  
Proliferative Retinopathy ◽  
Haemoglobin C

scholarly journals Factors associated with undernutrition among children with sickle cell disease attending the sickle cell clinic in Mulago National Referral Hospital, Uganda

2019 ◽  
Author(s):  
Rosta Asiimwe ◽  
Rornald Muhumuza Kananura ◽  
Richard Kajjura ◽  
Adoke Yeka
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Older Age ◽  
Referral Hospital ◽  
Childhood Mortality ◽  
Mulago Hospital ◽  
Cell Disease ◽  
Factors Associated ◽  
Mulago National Referral Hospital ◽  
National Referral Hospital

Abstract Background Sickle cell disease (SCD) is among the neglected non-communicable diseases, which significantly contributes to early childhood mortality. In Uganda, over 20,000 children are estimated to be sicklers. Undernutrition is common among children with SCD and contributes to increased morbidity and mortality. There is paucity of data on prevalence of undernutrition and associated factors in Uganda. Objective To assess the extent of undernutrition and related factors among children aged 5-12 years with SCD attending the sickle cell clinic at Mulago hospital, Uganda. Methods A total of 263 children with SCD attending the sickle cell clinic at Mulago National Referral hospital were recruited consecutively between May and June 2017. The nutritional status of the children was assessed by weight-for-age, BMI-for-age, and height-for-age z-scores calculated using STATA in accordance with WHO 2007 growth standards. Binomial regression was conducted to assess the predictors of undernutrition. Results About 20.2%, 11.4%, and 13.7% of the children were underweight, wasted and stunted respectively. Wasting was significantly associated with older age (10-12 years) (AOR=4.20, CI=2.18-8.10) and living in a female headed household (AOR=0.43, CI=0.19-0.99). Stunting was significantly associated with older age (10-12 years) (AOR=2.90, CI=1.39-6.06). Underweight was significantly associated with older age (10-12 years) (AOR=2.23, CI=1.05-5.16). Conclusion Underweight, wasting and stunting were prevalent among children with SCD attending Mulago hospital. The factors associated with undernutrition were older age and living in a female headed household.

scholarly journals Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management

Blood ◽  
2012 ◽  
Vol 120 (3) ◽  
pp. 528-537 ◽  
Author(s):  
Karina Yazdanbakhsh ◽  
Russell E. Ware ◽  
France Noizat-Pirenne
Keyword(s):  
Risk Factors ◽  
Sickle Cell Disease ◽  
Blood Cell ◽  
Sickle Cell ◽  
Red Blood Cell ◽  
Cell Disease ◽  
Factors Associated ◽  
Life Threatening ◽  
Red Blood Cell Transfusions ◽  
Transfusion Reactions

Abstract Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss the risk factors associated with alloimmunization with emphasis on possible mechanisms that can trigger delayed hemolytic transfusion reactions in sickle cell disease, and we describe the challenges in transfusion management of these patients, including opportunities and emerging approaches for minimizing this life-threatening complication.

scholarly journals BILATERAL ENDOPHTHALMITIS ASSOCIATED WITH SICKLE-CELL HAEMOGLOBIN C DISEASE

1964 ◽  
Vol 48 (12) ◽  
pp. 692-694 ◽  
Author(s):  
T. G. Davies ◽  
N. C. Bansal
Keyword(s):  
Sickle Cell ◽  
Haemoglobin C
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