scholarly journals Ischaemic optic neuropathy with painful ophthalmoplegia in diabetes mellitus.

1981 ◽  
Vol 65 (10) ◽  
pp. 673-678 ◽  
Author(s):  
D A Jabs ◽  
N R Miller ◽  
W R Green
Keyword(s):  
Diabetes Mellitus ◽  
Optic Neuropathy ◽  
Painful Ophthalmoplegia ◽  
Ischaemic Optic Neuropathy

scholarly journals Optic Neuritis in Patients with Type 2 Diabetes Mellitus: A Case Series

2021 ◽  
Author(s):  
Niharika Krishna Shetty ◽  
Divya Prasad
Keyword(s):  
Diabetes Mellitus ◽  
Optic Neuritis ◽  
Optic Neuropathy ◽  
Case Series ◽  
Methyl Prednisolone ◽  
Background Retinopathy ◽  
Ischaemic Optic Neuropathy ◽  
Ocular Movement ◽  
Time Of Presentation ◽  
Age Range

Diabetes mellitus is a group of metabolic disorders characterised by a high blood sugar level over a prolonged period of time. Ocular associations of diabetes include diabetic retinopathy, cataract, diabetic papillopathy, ocular movement disorders and optic neuritis. Optic neuritis is a clinical condition causing inflammation of the myelin sheet of optic nerve. This leads to alteration in the nerve conduction towards the brain. Diabetics are more commonly affected with anterior ischaemic optic neuropathy compared to papillitis or optic neuritis. The present case series is of diabetes associated papillitis. The patients were in the age range of 35-60 years. All the patients had poor visual acuity at presentation, mild disc oedema and disc elevation with no peripapillary haemorrhage, suggestive of papillitis. The patients had minimum background retinopathy and were hyperglycaemic at the time of presentation. The response to Intravenous (IV) methyl prednisolone, at a dose of 1 gm IV in 100 mL of normal saline, was good. Improvement to vision was seen within 3-5 days and improvement in colour vision was seen at the end of 11-15 days. Papillitis can be a manifestation of diabetes and should be kept as a differential diagnosis to non-arteritic ishaemic optic neuropathy. Optic neuropathies and background retinopathy may not co-exist. Poor systemic control of glycaemic level may directly co-relate to papillitis manifestation.

scholarly journals Non-Arteritic Anterior Ischaemic Optic Neuropathy: Treatment and Risk Factors

2020 ◽  
Vol 76 (2) ◽  
pp. 78-87
Author(s):  
Silvie Kalábová ◽  
Klára Marešová ◽  
Marta Karhanová
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Visual Acuity ◽  
Risk Factor ◽  
Optic Neuropathy ◽  
Systemic Risk ◽  
Systemic Disease ◽  
Department Of Ophthalmology ◽  
Ischaemic Optic Neuropathy ◽  
Anterior Ischaemic Optic Neuropathy

Aim: To ascertain whether various therapeutic procedures in non-arteritic anterior ischaemic optic neuropathy (NAION) have an impact on the resulting visual acuity of the affected eye. To assess the prevalence of risk factors that accompany this disease according to the literature. Methods: The retrospective study enrolled 55 eyes of 53 patients (41 men, 12 women) with an age range of 46 to 85 years (mean 64.9; median 64.0) who were hospitalized at the Department of Ophthalmology of the Faculty of Medicine and Dentistry and the University Hospital in Olomouc with the diagnosis of NAION between 2005 and 2016, and who received systemic treatment with intravenous vasodilators, either alone or in combination with intravenous corticosteroids. Central visual acuity (CVA) prior to treatment and immediately after its termination was evaluated. CVA was measured using the Snellen chart and is presented in decimal values. Using medical history data and medical records, the presence of systemic disease, namely hypertension, type 2 diabetes mellitus, and hypercholesterolaemia, was studied in these patients and evaluated for a possible association with NAION. Results: In the group of patients who were treated with intravenous vasodilators, the resulting CVA improved by 0.083 on average. In the group of patients who, in addition to vasodilator therapy, also received treatment with corticosteroids, the resulting CVA improved by only 0.03 on average. Although there was a more prominent improvement in CVA in the group treated with intravenous vasodilators alone, this difference was not statistically significant. At least one risk factor was found in the vast majority of the patients (96%). Eighty percent of the patients had hypertension, 43.6% of them were treated for diabetes mellitus, and 72.7% of the patients took drugs for hypercholesterolaemia. A combination of all these conditions was found in 36.4% of the patients. The proportion of smokers and past smokers did not exceed that of non-smokers. Conclusion: The mean improvement in the resulting CVA in patients after systemic therapy with vasodilators alone was greater than in those treated with a combination of vasodilators and corticosteroids; however, this difference was not statistically significant. In most patients in the group, at least one systemic risk factor was noted, most frequently hypertension. The prevalence rate of systemic risk factors was comparable to that reported in the literature.

scholarly journals Simultaneous and Bilateral Non-Arteritic Anterior Ischaemic Optic Neuropathy and Acute Angle-Closure

2021 ◽  
pp. 1-4
Author(s):  
Gerardo Esteban Cepeda-Ortegon ◽  
Alan Baltazar Treviño-Herrera ◽  
Abraham Olvera-Barrios ◽  
Alejandro Martínez-López-Portillo ◽  
Jesús Mohamed-Hamsho ◽  
...  
Keyword(s):  
Optic Neuropathy ◽  
Acute Angle ◽  
Angle Closure ◽  
Ischaemic Optic Neuropathy ◽  
Anterior Ischaemic Optic Neuropathy ◽  
Acute Angle Closure

scholarly journals Adalimumab and Non-Arteritic Anterior Ischaemic Optic Neuropathy: A Case Report

2014 ◽  
Vol 38 (5) ◽  
pp. 272-277 ◽  
Author(s):  
Krista Kinard ◽  
Jessica A. Walsh ◽  
Gopi K. Penmetsa ◽  
Judith E. A. Warner
Keyword(s):  
Case Report ◽  
Optic Neuropathy ◽  
Ischaemic Optic Neuropathy ◽  
Anterior Ischaemic Optic Neuropathy

scholarly journals Reply to: “Bilateral Non-arteritic Anterior Ischaemic Optic Neuropathy as the Presentation of Systemic Amyloidosis”

2017 ◽  
Vol 41 (6) ◽  
pp. 339-340
Author(s):  
Francesco Pellegrini ◽  
Daniele Cirone ◽  
Luca De Simone ◽  
Luca Cimino ◽  
Cristina Ciabattoni
Keyword(s):  
Optic Neuropathy ◽  
Systemic Amyloidosis ◽  
Ischaemic Optic Neuropathy ◽  
Anterior Ischaemic Optic Neuropathy

scholarly journals Macular thickness predictive of visual field sensitivity in ischaemic optic neuropathy

2012 ◽  
Vol 90 (6) ◽  
pp. e463-e469 ◽  
Author(s):  
Taras Papchenko ◽  
Brian T. Grainger ◽  
Peter J. Savino ◽  
Greg D. Gamble ◽  
Helen V. Danesh-Meyer
Keyword(s):  
Visual Field ◽  
Optic Neuropathy ◽  
Macular Thickness ◽  
Field Sensitivity ◽  
Ischaemic Optic Neuropathy
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