scholarly journals Age-related differences in the normal human cornea: a laser scanning in vivo confocal microscopy study

2007 ◽  
Vol 91 (9) ◽  
pp. 1165-1169 ◽  
Author(s):  
R L Niederer ◽  
D Perumal ◽  
T Sherwin ◽  
C N J McGhee
Keyword(s):  
Confocal Microscopy ◽  
Laser Scanning ◽  
Microscopy Study ◽  
Human Cornea ◽  
In Vivo Confocal Microscopy ◽  
Age Related ◽  
Normal Human

Epithelial Dendritic Cell Distribution in Normal and Inflamed Human Cornea: In Vivo Confocal Microscopy Study

2006 ◽  
Vol 142 (5) ◽  
pp. 736-744.e2 ◽  
Author(s):  
Leonardo Mastropasqua ◽  
Mario Nubile ◽  
Manuela Lanzini ◽  
Paolo Carpineto ◽  
Marco Ciancaglini ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Confocal Microscopy ◽  
Microscopy Study ◽  
Human Cornea ◽  
Cell Distribution ◽  
In Vivo Confocal Microscopy

Identification of presumed corneal neuromas and microneuromas using laser-scanning in vivo confocal microscopy: a systematic review

2021 ◽  
pp. bjophthalmol-2020-318156
Author(s):  
Holly Rose Chinnery ◽  
Rajni Rajan ◽  
Haihan Jiao ◽  
Mengliang Wu ◽  
Alexis Ceecee Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Confocal Microscopy ◽  
Laser Scanning ◽  
Cochrane Library ◽  
Human Cornea ◽  
In Vivo Confocal Microscopy ◽  
Ovid Medline ◽  
Corneal Nerves ◽  
Corneal Nerve

Background/aimsThis systematic review critically evaluated peer-reviewed publications describing morphological features consistent with, or using terms related to, a ‘neuroma’ or ‘microneuroma’ in the human cornea using laser-scanning in vivo confocal microscopy (IVCM).MethodsThe review was prospectively registered on PROSPERO (CRD42020160038). Comprehensive literature searches were performed in Ovid MEDLINE, Ovid Embase and the Cochrane Library in November 2019. The review included primary research studies and reviews that described laser-scanning IVCM for examining human corneal nerves. Papers had to include at least one of a pre-specified set of keyword stems, broadly related to neuromas and microneuromas, to describe a corneal nerve feature.ResultsTwenty-five papers (20 original studies; 5 reviews) were eligible. Three original studies evaluated corneal nerve features in healthy eyes. Most papers assessed corneal nerves in ocular and systemic conditions; seven studies did not include a control/comparator group. There was overlap in terminology used to describe nerve features in healthy and diseased corneas (eg, bulb-like/bulbous, penetration, end/s/ing). Inspection of IVCM images within the papers revealed that features termed ‘neuromas’ and ‘microneuromas’ could potentially be physiological corneal stromal-epithelial nerve penetration sites. We identified inconsistent definitions for terms, and limitations in IVCM image acquisition, sampling and/or reporting that may introduce bias and lead to inaccurate representation of physiological nerve characteristics as pathological.ConclusionThese findings identify a need for consistent nomenclature and definitions, and rigorous IVCM scanning and analysis protocols to clarify the prevalence of physiological, as opposed to pathological, corneal nerve features.

Conjunctival findings in hyperbaric and low-tension glaucoma: an in vivo confocal microscopy study

2011 ◽  
Vol 90 (2) ◽  
pp. e132-e137 ◽  
Author(s):  
Luca Agnifili ◽  
Paolo Carpineto ◽  
Vincenzo Fasanella ◽  
Rodolfo Mastropasqua ◽  
Antonio Zappacosta ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Microscopy Study ◽  
In Vivo Confocal Microscopy ◽  
Low Tension Glaucoma ◽  
Low Tension

scholarly journals Cellular morphological changes detected by laser scanning in vivo confocal microscopy associated with clinical outcome in fungal keratitis

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jaya D. Chidambaram ◽  
Namperumalsamy V. Prajna ◽  
Srikanthi Palepu ◽  
Shruti Lanjewar ◽  
Manisha Shah ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Clinical Outcome ◽  
Laser Scanning ◽  
Morphological Changes ◽  
Fungal Keratitis ◽  
In Vivo Confocal Microscopy
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