scholarly journals Physical activity and the 15-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study

2006 ◽  
Vol 90 (12) ◽  
pp. 1461-1463 ◽  
Author(s):  
M D Knudtson ◽  
R Klein ◽  
B E K Klein
Keyword(s):  
Physical Activity ◽  
Macular Degeneration ◽  
Cumulative Incidence ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam

scholarly journals The Relationship of Atherosclerosis to the 10-Year Cumulative Incidence of Age-related Macular Degeneration: The Beaver Dam Studies

Ophthalmology ◽  
2013 ◽  
Vol 120 (5) ◽  
pp. 1012-1019 ◽  
Author(s):  
Ronald Klein ◽  
Karen J. Cruickshanks ◽  
Chelsea E. Myers ◽  
Theru A. Sivakumaran ◽  
Sudha K. Iyengar ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Cumulative Incidence ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam ◽  
Relationship Of ◽  
The Relationship

scholarly journals Skin Intrinsic Fluorescence and Age-Related Macular Degeneration: The Beaver Dam Eye Study

2017 ◽  
Vol 58 (14) ◽  
pp. 6328 ◽  
Author(s):  
Ronald Klein ◽  
Kristine E. Lee ◽  
John D. Maynard ◽  
Stacy M. Meuer ◽  
Ronald E. Gangnon ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Intrinsic Fluorescence ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam ◽  
Skin Intrinsic Fluorescence

Physical Activity and Age-related Macular Degeneration: A Systematic Literature Review and Meta-analysis

2017 ◽  
Vol 180 ◽  
pp. 29-38 ◽  
Author(s):  
Myra B. McGuinness ◽  
Jerome Le ◽  
Paul Mitchell ◽  
Bamini Gopinath ◽  
Ester Cerin ◽  
...  
Keyword(s):  
Physical Activity ◽  
Literature Review ◽  
Macular Degeneration ◽  
Systematic Literature Review ◽  
Meta Analysis ◽  
Age Related Macular Degeneration ◽  
Age Related

Frailty and Age-related Macular Degeneration: The Beaver Dam Eye Study

2005 ◽  
Vol 140 (1) ◽  
pp. 129-131 ◽  
Author(s):  
Ronald Klein ◽  
Barbara E.K. Klein ◽  
Michael D. Knudtson
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam

scholarly journals Small Drusen and Age-Related Macular Degeneration: The Beaver Dam Eye Study

2015 ◽  
Vol 4 (3) ◽  
pp. 425-440 ◽  
Author(s):  
Ronald Klein ◽  
Chelsea Myers ◽  
Kristine Lee ◽  
Ronald Gangnon ◽  
Theru Sivakumaran ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam

scholarly journals Five-year cumulative incidence and progression of age-related macular degeneration: results from the German population-based Gutenberg Health Study (GHS)

2021 ◽  
Author(s):  
Christina A. Korb ◽  
Hisham Elbaz ◽  
Alexander K. Schuster ◽  
Stefan Nickels ◽  
Katharina A. Ponto ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Cumulative Incidence ◽  
Population Based ◽  
Age Related Macular Degeneration ◽  
Fundus Photography ◽  
Health Study ◽  
German Population ◽  
Gutenberg Health Study ◽  
Age Related

Abstract Purpose Age-related macular degeneration (AMD) is a major cause of visual impairment and blindness. This study evaluates the incidence and progression of AMD in a large German cohort. Methods The Gutenberg Health Study (GHS) is a population-based, prospective, observational cohort study in Germany that includes 15,010 participants between 35 and 74 years of age. The baseline examination, including fundus photography, was conducted between 2007 and 2012, and the 5-year follow-up examination was performed between 2012 and 2017. AMD grading of fundus photographs was performed according to the Rotterdam Eye Study classification. The 5-year cumulative incidence and progression of AMD were calculated. Poisson regression analysis was conducted to investigate factors associated with the cumulative incidence and progression of AMD. Results Six-thousand-eight-hundred-eighty-eight participants (49.8%, n = 3427 female) were included in the analysis. AMD prevalence was 8.5% [95% CI: 7.9–9.2%] at baseline and 10.3% [95% CI: 9.6–11.1%] at follow-up. The cumulative 5-year-incidence was 2.0% [1.7–2.4%]. AMD progression within 5 years was seen in 18.1% [95% CI: 15.1–21.5%] of the participants. AMD incidence and AMD progression were associated with higher age, for each 10-year increase in age, the risk of AMD doubles (RR = 2.30), and the risk of progression of the disease is increased by 1.6. while AMD incidence also with pseudophakic status. Conclusions In summary, this population-based sample provides substantial epidemiologic data from a large German cohort, including data on progression and cumulative incidence of macular degeneration in younger age groups. AMD progression over 5 years is common in the German population, 18.1% of subjects with AMD showed progression in at least one eye in this time frame and is associated with higher age. Nevertheless, although usually defined to occur over the age of 50, in this cohort AMD occurred in 0.5% and AMD progression occurred in 5.4% of those already affected in the youngest age group before 50 years of age.

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