scholarly journals COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?

2021 ◽  
Vol 14 (4) ◽  
pp. e241663
Author(s):  
Shweta Mallikarjun Revannavar ◽  
Supriya P S ◽  
Laxminarayana Samaga ◽  
Vineeth V K

A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. She incidentally tested positive for COVID-19. CT paranasal sinus and MRI brain revealed left-sided pansinusitis with acute infarct in the left parieto-occipital region without angioinvasion. An emergency functional endoscopic sinus procedure was done, which confirmed mucormycosis on histopathological examination. After 1 week of conventional amphotericin B and antibiotics, repeat CT brain showed improvement in mucosal thickening and sinusitis. This case is a rare presentation of mucormycosis associated with rapid progression to orbital apex syndrome with brain infarction in a patient with non-ketotic diabetes and COVID-19. Early diagnosis and treatment are essential to prevent further end-organ damage. It is also interesting that there was no angioinvasion and transient periarterial inflammation was attributed to brain infarction.

2021 ◽  
pp. 29-30
Author(s):  
Varsha Konyala ◽  
Poornima M

Tuberculosis is notorious for its afiction to the lungs.However, one mustn't forget the case burden that extra pulmonary TB imposes.Here we present a case of a middle aged woman who came with non specic complaints per abdomen.Her abdominal pain, discomfort, loss of weight and appetite along with clinical examination and investigations pointed towards malignancy. On surgical exploration and histopathological examination, the case was conrmed as that of abdominal TB.Tuberculosis of the abdomen is one of the extra pulmonary sites where tubercular bacilli can reside. In such cases, apart from treating tuberculosis medically with anti tubercular therapy, one must also order a chest X-ray to identify any pulmonary foci of tuberculosis. This is to curb any potential spread of infection. Further, one must look acutely at cases with non specic ndings and consider TB in the differential diagnosis, particularly if the patient hails from a TB endemic region.With a keen eye for tuberculosis along with corroborative and relevant investigations, one can diagnose this chronic illness and put patients well on the road to recovery.


Author(s):  
Tanweerul Huda ◽  
Tarun Sutrave ◽  
Bharati Pandya

Dermoid cysts are benign lesions that grow slowly and can occur anywhere in the body. Clitoris is an extremely rare site for dermoids cysts. We present a case of inclusion cyst of clitoris in a middle aged woman, who had it for 10 years before presenting for relief from her symptoms. Local examination revealed a 3 cm X 4 cm size cystic mass at the clitoris giving it an appearance of clitoromegaly. She underwent an excision of the cyst at our hospital with the histopathology report suggesting the lesion to be a dermoid cyst. Postoperative recovery was uneventful with no evidence of recurrence on follow up.


2018 ◽  
pp. bcr-2017-222980
Author(s):  
FNU Salman ◽  
Muhammad Ihtesham Khan ◽  
Ishtiaq Hussain ◽  
Hafez Mohammad Ammar Abdullah

Author(s):  
Toh Leong Tan ◽  
Chuan Hun Ding

Hypertensive crises can be life-threatening if undiagnosed due to the risk of acute target organ damage. This is a case of a middle-aged woman with poorly controlled hypertension who presented with a 3-day history of dyspnea, orthopnea, and cough productive of frothy sputum. Repeated attempts to measure her blood pressure (BP) using both a mercury and an electronic sphygmomanometer were unsuccessful. However, when an arterial catheterization of the right radial artery was performed, her mean BP was 358/151 mm Hg. A chest X-ray revealed cardiomegaly with plethoric lung fields. Following a diagnosis of hypertensive emergency with acute pulmonary edema, a glyceryl trinitrate infusion at a dose of 20 mg/min was commenced and titrated in an escalating manner. She was also given a single dose of intravenous frusemide 40 mg. Her BP was successfully reduced by 25% within 3 h of presentation.


2020 ◽  
Author(s):  
Fernando Fonseca Gonçalves ◽  
João Pedro Monteiro ◽  
Fátima São Neves ◽  
José Ilídio Moreira

Abstract Background: Ventricular free wall rupture is an uncommon but potentially fatal mechanical complication following a myocardial infarction.Case presentation: We report a case of a 51 year-old female admitted in our emergency department in cardiogenic shock, in which echocardiography was fundamental in the diagnosis of a left ventricle free wall rupture with tamponade. In this case, removal of pericardial clots with subsequent hemodynamic improvement and the presence of a strong adhesion between the pericardial layers at the rupture site were sufficient for the short-term surgical treatment. The patient remained stable and was discharged fifteen days later.Conclusions: Although being a rare presentation, this unconventional surgical approach might be useful in this kind of cases.


2021 ◽  
Vol 14 (10) ◽  
pp. e243563
Author(s):  
Rehan Nasir Khan ◽  
Zehra Kazmi ◽  
Lubna Mushtaque Vohra ◽  
Zeeshan Uddin

Synchronous primary malignancies are most frequently seen with cancers of the stomach and oesophagus, mainly attributed to the similar genetic mutations. Most of these multiple malignancies turn out to be metastatic or metachronous lesions. Multiple synchronous malignancies are rarer than metachronous ones. Primary synchronous breast and renal cancer is even rare. These patients require extensive workup to exclude all possible metastases. The nature of the primary tumours must also be confirmed, prior to any treatment strategy. We report the case of a healthy, middle-aged woman who initially presented with a lesion suspicious for breast carcinoma, and further workup revealed the presence of an asymptomatic, synchronous primary renal cell cancer, which is a very rare presentation.


2019 ◽  
Vol 12 (1) ◽  
pp. bcr-2018-225851 ◽  
Author(s):  
Amna Bibi ◽  
Chathuri Liyanapthirana ◽  
Sajjad Khan

This is a case of a female patient presented with a mild headache associated with recurrent episodes of nausea and vomiting, confusion and right-sided hemiparesis, diagnosed of haemorrhagic venous infarction from the thrombosis of left transverse and sigmoid sinus and probably the left vein of Labbe. She had severe microcytic hypochromic anaemia due to iron deficiency, without any other risk factors for cerebral venous thrombosis such as trauma history, infections, coagulation disorders or autoimmune diseases. She had a good prognosis after iron supplementation and anticoagulation therapy.


2018 ◽  
Vol 5 (1) ◽  
pp. 4
Author(s):  
Bart Vrugt ◽  
Thomas Frauenfelder ◽  
Holger Dressel ◽  
Fabio Barresi ◽  
Christian Clarenbach ◽  
...  

Pleuroparenchymal fibro-elastosis (PPFE) is a rare idiopathic interstitial pneumonia. Secondary forms of PPFE may occur in patients following lung- or bone marrow transplantation. Here we report a middle-aged woman who presented with dyspnea and cough. She had been working as a cleaning woman in an agriculture company and logistic firm. Chest HRCT was highly suggestive for PPFE. Histopathological examination of a surgical biopsy showed a pattern of PPFE with airway-centered fibro-elastosis, constrictive bronchiolitis and birefringent particles in the pathological areas only. Using transmission electron microscopy with X-ray diffraction (TEM/EDX) these particles were identified as quartz and silicates, both components generally found in soil. The present case illustrates that secondary PPFE may result from agricultural dust exposure and stresses the need for a careful workup of the occupational history.


2021 ◽  
Vol 14 (8) ◽  
pp. e240687
Author(s):  
Vivek Srivastava ◽  
Pratik K Jha ◽  
Awgesh Kumar Verma ◽  
Mumtaz Ahmad Ansari

Aggressive angiomyxoma is a rare and locally aggressive mesenchymal tumour, predominantly occurring in women of reproductive age group. The term aggressive is attributed to the infiltrative nature and frequent local recurrences. They arise commonly from the vulvovaginal region, perineum or pelvis and are usually misdiagnosed as other common entities in these regions. Radiological investigations aid in the diagnosis and planning of surgery. However, the final diagnosis in most of the cases is established by histopathological examination. We herein report a case of a middle-aged woman presenting with recurrent large right vulvar mass highlighting the surgical challenges posed by its intrapelvic extension.


2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Mohd. Zahid ◽  
Sohail Ahamed ◽  
Jitesh Kumar Jain ◽  
Ravish Chabra

Vertebra plana is a rare presentation of spinal lymphoma. When radiological picture of a patient of paraplegia presents vertebra plana, diagnosis becomes a challenge. In a developing country like India tuberculosis should also be a consideration. Even histology sometimes fails to conclude a diagnosis. Immunohistochemistry is of immense help in clinching a diagnosis.


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