Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components

M. Dougados; B. Combe; A. Cantagrel; P. Goupille; P. Olive; M. Schattenkirchner; S Meusser; L Paimela; R. Rau; H. Zeidler; M. Leirisalo-Repo; K. Peldan

doi:10.1136/ard.58.4.220

Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components

Annals of the Rheumatic Diseases ◽

10.1136/ard.58.4.220 ◽

1999 ◽

Vol 58 (4) ◽

pp. 220-225 ◽

Cited By ~ 164

Author(s):

M. Dougados ◽

B. Combe ◽

A. Cantagrel ◽

P. Goupille ◽

P. Olive ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Combination Therapy ◽

Early Rheumatoid Arthritis ◽

Double Blind ◽

Randomised Controlled

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Cyclosporin A monotherapy versus cyclosporin A and methotrexate combination therapy in patients with early rheumatoid arthritis: a double blind randomised placebo controlled trial

Annals of the Rheumatic Diseases ◽

10.1136/ard.62.4.291 ◽

2003 ◽

Vol 62 (4) ◽

pp. 291-296 ◽

Cited By ~ 59

Author(s):

A H Gerards

Keyword(s):

Rheumatoid Arthritis ◽

Combination Therapy ◽

Cyclosporin A ◽

Early Rheumatoid Arthritis ◽

Controlled Trial ◽

Double Blind

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Long term structural effects of combination therapy in patients with early rheumatoid arthritis: five year follow up of a prospective double blind controlled study

Annals of the Rheumatic Diseases ◽

10.1136/ard.62.8.764 ◽

2003 ◽

Vol 62 (8) ◽

pp. 764-766 ◽

Cited By ~ 29

Author(s):

J F Maillefert

Keyword(s):

Rheumatoid Arthritis ◽

Combination Therapy ◽

Early Rheumatoid Arthritis ◽

Controlled Study ◽

Structural Effects ◽

Double Blind

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Infliximab for 6 months added on combination therapy in early rheumatoid arthritis: 2-year results from an investigator-initiated, randomised, double-blind, placebo-controlled study (the NEO-RACo Study)

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2012-201365 ◽

2012 ◽

Vol 72 (6) ◽

pp. 851-857 ◽

Cited By ~ 56

Author(s):

Marjatta Leirisalo-Repo ◽

Hannu Kautiainen ◽

Leena Laasonen ◽

Markku Korpela ◽

Markku J Kauppi ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Combination Therapy ◽

Early Rheumatoid Arthritis ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo

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A multicenter, randomized, double-blind clinical trial of combination therapy with Anbainuo, a novel recombinant human TNFRII:Fc fusion protein, plus methotrexate versus methotrexate alone or Anbainuo alone in Chinese patients with moderate to severe rheumatoid arthritis

Clinical Rheumatology ◽

10.1007/s10067-012-2096-z ◽

2012 ◽

Vol 32 (1) ◽

pp. 99-108 ◽

Cited By ~ 8

Author(s):

Xiao-Xiang Chen ◽

Qing Dai ◽

An-Bin Huang ◽

Hua-Xiang Wu ◽

Dong-Bao Zhao ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Combination Therapy ◽

Fusion Protein ◽

Chinese Patients ◽

Severe Rheumatoid Arthritis ◽

Double Blind ◽

Double Blind Clinical Trial

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The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment

Arthritis & Rheumatism ◽

10.1002/art.21519 ◽

2005 ◽

Vol 54 (1) ◽

pp. 26-37 ◽

Cited By ~ 1157

Author(s):

Ferdinand C. Breedveld ◽

Michael H. Weisman ◽

Arthur F. Kavanaugh ◽

Stanley B. Cohen ◽

Karel Pavelka ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Combination Therapy ◽

Double Blind ◽

Double Blind Clinical Trial ◽

Methotrexate Treatment

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Faculty Opinions recommendation of The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14174.471676 ◽

2006 ◽

Author(s):

Diego Kyburz

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Combination Therapy ◽

Double Blind ◽

Double Blind Clinical Trial ◽

Methotrexate Treatment

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Study design and rationale of "Synergistic Effect of Combination Therapy with Cilostazol and ProbUcol on Plaque Stabilization and Lesion REgression (SECURE)" study: a double-blind randomised controlled multicenter clinical trial

Trials ◽

10.1186/1745-6215-12-10 ◽

2011 ◽

Vol 12 (1) ◽

Cited By ~ 7

Author(s):

Young-Guk Ko ◽

◽

Byeong-Keuk Kim ◽

Byoung Kwon Lee ◽

Woong Chol Kang ◽

...

Keyword(s):

Clinical Trial ◽

Combination Therapy ◽

Synergistic Effect ◽

Study Design ◽

Multicenter Clinical Trial ◽

Double Blind ◽

Plaque Stabilization ◽

Lesion Regression ◽

Randomised Controlled

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Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: a randomized, controlled, double-blind, 52 week clinical trial

Rheumatology ◽

10.1093/rheumatology/36.10.1082 ◽

1997 ◽

Vol 36 (10) ◽

pp. 1082-1088 ◽

Cited By ~ 143

Author(s):

C. J. Haagsma ◽

P. L. van Riel ◽

A. J. de Jong ◽

L. B. van de Putte

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Early Rheumatoid Arthritis ◽

Double Blind ◽

Randomized Controlled

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THU0183 Less pain over 2 years with biological compared to conventional combination therapy in early rheumatoid arthritis: results from the randomised controlled swefot trial

10.1136/annrheumdis-2018-eular.1844 ◽

2018 ◽

Author(s):

T. Olofsson ◽

J.K. Wallman ◽

A. Jöud ◽

M.E. Schelin ◽

S. Ernestam ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Combination Therapy ◽

Early Rheumatoid Arthritis ◽

Randomised Controlled

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Faculty Opinions recommendation of MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial (CIMESTRA).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1158507.618812 ◽

2009 ◽

Author(s):

Jacques Morel

Keyword(s):

Rheumatoid Arthritis ◽

Randomised Controlled Trial ◽

Early Rheumatoid Arthritis ◽

Radiographic Progression ◽

Controlled Trial ◽

Randomised Controlled ◽

Bone Oedema

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