scholarly journals Polymorphonuclear leucocyte function and previous yersinia arthritis: enhanced chemokinetic migration and oxygen radical production correlate with the severity of the acute disease.

1987 ◽  
Vol 46 (4) ◽  
pp. 307-313 ◽  
Author(s):  
P Koivuranta-Vaara ◽  
M Leirisalo-Repo ◽  
H Repo
Keyword(s):  
Oxygen Radical ◽  
Polymorphonuclear Leucocyte ◽  
Acute Disease ◽  
Radical Production ◽  
Oxygen Radical Production ◽  
Yersinia Arthritis

Neutrophil oxygen radical production in pre-eclampsia with HELLP syndrome

2001 ◽  
Vol 99 (2) ◽  
pp. 213-218 ◽  
Author(s):  
Petra L.M Zusterzeel ◽  
Geert J.A Wanten ◽  
Wilbert H.M Peters ◽  
Hans M.W.M Merkus ◽  
Eric A.P Steegers
Keyword(s):  
Hellp Syndrome ◽  
Oxygen Radical ◽  
Radical Production ◽  
Oxygen Radical Production

Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production

1999 ◽  
Vol 57 (6) ◽  
pp. 705-712 ◽  
Author(s):  
Dae-Sig Jang ◽  
Bo-Seong Kang ◽  
Shi Yong Ryu ◽  
IL-Moo Chang ◽  
Kyung Rak Min ◽  
...  
Keyword(s):  
Oxygen Radical ◽  
Inhibitory Effects ◽  
Radical Production ◽  
Oxygen Radical Production ◽  
Resveratrol Analogs

Measurements of Mitochondrial Oxygen Radical Production

1998 ◽  
pp. 533-548 ◽  
Author(s):  
Yusen Liu ◽  
Nikki Holbrook ◽  
Gertrude Kokkonen ◽  
Shoichi Kitano ◽  
George Roth
Keyword(s):  
Oxygen Radical ◽  
Radical Production ◽  
Oxygen Radical Production

Oxygen radical production by transformed B lymphocytes

1991 ◽  
Vol 12 (2) ◽  
pp. 87-92 ◽  
Author(s):  
Owen T.G. Jones ◽  
John T. Hancock ◽  
Lydia M. Henderson
Keyword(s):  
B Lymphocytes ◽  
Oxygen Radical ◽  
Radical Production ◽  
Oxygen Radical Production

scholarly journals Statin-Induced Heme Oxygenase-1 Increases NF-κB Activation and Oxygen Radical Production in Cultured Neuronal Cells Exposed to Lipopolysaccharide

2007 ◽  
Vol 102 (1) ◽  
pp. 150-159 ◽  
Author(s):  
Ching-Hua Hsieh ◽  
Seng-Feng Jeng ◽  
Min-Wei Hsieh ◽  
Yi-Chun Chen ◽  
Cheng-Shyuan Rau ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Neuronal Cells ◽  
Oxygen Radical ◽  
Heme Oxygenase 1 ◽  
Radical Production ◽  
Oxygen Radical Production

Attenuation of acute lung injury and oxygen radical production by the 21-aminosteroid, U-78518F

1993 ◽  
Vol 74 (5) ◽  
pp. 2155-2160 ◽  
Author(s):  
T. Tanigaki ◽  
Y. Suzuki ◽  
D. Heimer ◽  
H. H. Sussman ◽  
W. G. Ross ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Acute Lung Injury ◽  
Lung Injury ◽  
Phorbol Myristate Acetate ◽  
Guinea Pigs ◽  
Oxygen Radical ◽  
Myristate Acetate ◽  
E Coli ◽  
Radical Production ◽  
Oxygen Radical Production

Oxygen radicals play an important role in the mechanism of acute lung injury. The 21-aminosteroid lazaroid, U-78518F, is a potent antioxidant. We examined the effect of intravenous U-78518F on acute lung injury in septic guinea pigs over 8 h. The experimental groups (n = 6) were 1) saline control, 2) Escherichia coli (2 x 10(9)/kg i.v.), 3) pretreatment (U-78518F 5 mg/kg bolus + 1 mg.kg-1 x h-1, 15 min before E. coli injection), and 4) posttreatment (U-78518F 30 min after E. coli injection). We measured wet-to-dry weight ratio (W/D) as an index of pulmonary edema and concentration ratios of 125I-labeled albumin in lung tissue and bronchoalveolar lavage fluid compared with plasma (L/P and BAL/P, respectively) as indexes of lung protein fluxes. In septic guinea pigs, pretreatment with U-78518F attenuated W/D, L/P, and BAL/P and posttreatment attenuated W/D and BAL/P (P < 0.05 for each). Furthermore, we studied the effect of U-78518F on human neutrophil oxygen radical production (ORP) by using flow cytometry to assess intracellular ORP and lucigenin-dependent chemiluminescence to assess extracellular ORP. Neutrophils (5 x 10(5) were stimulated with 0.5 micrograms/ml of phorbol myristate acetate. With flow cytometry, we measured intracellular ORP, cross-sectional cell area, and degranulation in neutrophils. U-78518F (minimum concn 1.0 microM) decreased intracellular ORP (n = 4; P < 0.05) when the dihydrorhodamine 123 assay was used. U-78518F (minimum concn 1.0 microM) inhibited phorbol myristate acetate-induced neutrophil chemiluminescence (n = 4; P < 0.05).

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