scholarly journals 99mTc HMDP bone scanning in generalised nodal osteoarthritis. I. Comparison of the standard radiograph and four hour bone scan image of the hand.

1986 ◽  
Vol 45 (8) ◽  
pp. 617-621 ◽  
Author(s):  
C W Hutton ◽  
E R Higgs ◽  
P C Jackson ◽  
I Watt ◽  
P A Dieppe
Keyword(s):  
Bone Scan ◽  
Bone Scanning ◽  
Standard Radiograph

3-phase Technicium-99m bone scanning in patients with pain in the hip region after cemented total hip replacement: a multicentre series of 100 cases

2017 ◽  
Vol 28 (3) ◽  
pp. 259-265 ◽  
Author(s):  
Daniel S Hill ◽  
Soulat Naim ◽  
Roy J Powell ◽  
Denis Kinsella ◽  
Andrew D Toms ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Confidence Interval ◽  
Total Hip Replacement ◽  
Hip Replacement ◽  
Bone Scan ◽  
Revision Arthroplasty ◽  
Microbiological Analysis ◽  
Bone Scanning ◽  
Concurrent Infection ◽  
Total Hip

Introduction: The aim of this study was to assess the benefit of a Technetium-99M (HDP) 3-phase bone scan (TPBS) as an additional diagnostic test in the evaluation of pain in the hip region following cemented total hip replacement (THR) surgery. Methods: A retrospective study over a 24-month period was performed comprising 100 patients investigated with a TPBS. Investigations were summarised and analysed, and were classified as entirely normal, possibly abnormal, and definitely abnormal. Results: 45% (45) of TPBSs were reported as being entirely normal, 50% (50) as possibly abnormal, and 5% (5) as definitely abnormal. During the 24-month study period 230 revision THR procedures were performed at our institution; 10% (24) were investigated with TPBS and 90% (206) were not. 29% (7/24) of patients investigated with a TPBS that subsequently underwent revision THR surgery had an entirely normal preoperative TPBS. 84% (38) with an abnormal TPBS were managed conservatively. A TPBS had a sensitivity of 29% (95% confidence interval (CI), 13%-51%) and a specificity of 50% (95% CI, 38%-62%) in the detection of infection, or loosening with concurrent infection. Conclusion: A TPBS should only be considered following clinical evaluation, serological investigation, diagnostic imaging and microbiological analysis of fluid obtained from arthrocentesis by a specialist revision arthroplasty surgeon. A TPBS may be useful in the situation where abnormal serology is present, but where repeated joint aspirations samples are inconclusive.

Bone metastases in patients with gastrinomas: a prospective study of bone scanning, somatostatin receptor scanning, and magnetic resonance image in their detection, frequency, location, and effect of their detection on management.

1998 ◽  
Vol 16 (3) ◽  
pp. 1040-1053 ◽  
Author(s):  
F Gibril ◽  
J L Doppman ◽  
J C Reynolds ◽  
C C Chen ◽  
V E Sutliff ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Liver Metastases ◽  
Bone Metastases ◽  
Bone Scan ◽  
Somatostatin Receptor ◽  
Axial Skeleton ◽  
Bone Lesions ◽  
Endocrine Tumors ◽  
Bone Scanning ◽  
Imaging Results

PURPOSE To determine whether bone scan, magnetic resonance imaging (MRI), or somatostatin receptor scintigraphy (SRS) is best for identifying bone metastases in patients with gastrinomas, as well as their frequency and location, whether their detection affects management, and what patient subgroups should be examined. MATERIALS AND METHODS One hundred fifteen patients with gastrinoma were prospectively studied. Patients were examined yearly and those with liver metastases were reexamined every 3 months. Based on clinical history, histology, growth pattern, and development of new bone lesions, possible bone metastases were classified as to whether they were or were not bone metastases. Imaging results were correlated at different times in the disease course and with disease extent. RESULTS Bone scan was positive in 52 patients, MRI in seven, and SRS in six. Eight patients (7%) were determined to have bone metastases and MRI was correctly positive in seven, SRS in six, and bone scan in five. SRS or MRI was positive in all patients with bone metastases. Bone scan had significantly lower specificity and sensitivity, and a higher rate (P < .02) of false-negative results than MRI or SRS. Bone metastases occurred in 31% of patients with liver metastases and 0% with only lymph node metastases. The initial bone metastases were in the spine or sacrum (75%) followed in descending order by the pelvis or sacroiliac joints (38%), scapula or shoulder, and ribs. In all cases, detection of bone metastases changed the management. CONCLUSION SRS and MRI, because of high sensitivity and specificity, are recommended over bone scanning to screen for bone metastases in patients with gastrinomas. However, because bone metastases can occur initially outside the axial skeleton, SRS is the recommended initial localization method of choice. Bone metastases occur in 7% of all patients and 31% of patients with liver metastases, only occur in patients with liver metastases, are usually in the axial skeleton initially, and their detection changes management in all cases. Patients with pancreatic endocrine tumors with liver metastases should undergo SRS every 6 months to 1 year to detect bone metastases.

Correlation of Bone SPECT Scintigraphy with Histopathology of the Ethmoid Bulla: Preliminary Investigation

2007 ◽  
Vol 116 (9) ◽  
pp. 647-652 ◽  
Author(s):  
Peter J. Catalano ◽  
Robert Dolan ◽  
John Romanow ◽  
Spencer C. Payne ◽  
Mark Silverman
Keyword(s):  
Bone Scan ◽  
Photon Emission ◽  
Disease Process ◽  
Spect Imaging ◽  
Sinus Surgery ◽  
Response To Treatment ◽  
Emission Computed Tomography ◽  
Bone Scanning ◽  
Technetium 99M ◽  
Methylene Diphosphonate

Objectives: Reports in the rhinology literature suggest that osteitis of the ethmoid bone may be responsible for refractory and/or recurrent sinusitis. If so, bone scanning technologies capable of detecting osteitis may be useful in diagnosing this condition and its response to treatment. The objective of this prospective cohort study was to determine the correlation of single photon emission computed tomography (SPECT) bone scintigraphy with the histopathology of the ethmoid bulla. Methods: Thirty-six patients with a diagnosis of chronic sinusitis who were scheduled to undergo sinus surgery underwent a presurgical SPECT bone scan using technetium 99m-methylene diphosphonate. All bone scans were done within 5 days of surgery. During the procedure, bone samples from the face of the ethmoid bulla were obtained and examined by a pathologist blinded to the bone scan result. In this study, histopathology consistent with osteitis was defined as a change from lamellar to woven bone. A positive bone scan was defined by the presence of increased radiotracer uptake in the ethmoid sinuses. Results: Thirty-two of the 36 patients had a positive bone scan on SPECT imaging, and 31 specimens demonstrated histopathologic bone changes consistent with osteitis, for a sensitivity of 93.9%. An additional 4 patients had a negative bone scan on SPECT imaging, and osteitis was identified in 2 of the 4. The specificity was 66.7%, and the positive predictive value was 96.9%. Conclusions: We found that SPECT bone scanning with technetium 99m-methylene diphosphonate is a highly sensitive test for identifying osteitis in patients with chronic rhinosinusitis. It may be a useful tool in the armamentarium of the otolaryngologist to better define this disease process.

The Prognostic Value of Quantitative Bone Scan in Knee Osteochondritis Dissecans

1998 ◽  
Vol 26 (1) ◽  
pp. 7-14 ◽  
Author(s):  
George A. Paletta ◽  
Paul A. Bednarz ◽  
Carl L. Stanitski ◽  
G.A. Sandman ◽  
Deborah F. Stanitski ◽  
...  
Keyword(s):  
Osteochondritis Dissecans ◽  
Predictive Value ◽  
Prognostic Value ◽  
Bone Scan ◽  
Osteochondral Lesion ◽  
Healing Time ◽  
Nonsurgical Treatment ◽  
Bone Scanning ◽  
Open Physes ◽  
Increased Activity

We reviewed the records of 12 patients ages 9 to 16 years with knee osteochondritis dissecans. All patients had clinical histories and examinations, four radiographic views of the knee, and technetium-99m diphosphonate quantitative bone scans. Scan results (symmetric, increased, or decreased activity), clinical course, healing time, and final outcome were correlated to determine the prognostic value of the scan. We divided the patients into those with open physes (distal femoral and proximal tibial) and those with closed physes. Four of the six patients with open physes had increased activity on the bone scan. All four of these knees healed with nonsurgical treatment. The other two patients had decreased activity on bone scan, and both required surgical treatment after nonsurgical treatment failed. Of the six patients with closed physes, all had increased activity on the bone scan, but only two patients had healing of the osteochondral lesion without surgery. Quantitative bone scanning had a 100% predictive value for the prognosis in osteochondritis dissecans patients with open physes, but for those with closed physes the predictive value was less. Because the natural history in the adolescent group is less predictable, it is in this group that the quantitative scan would be most helpful. In this small group of patients, quantitative bone scanning had limited prognostic value.

Occult Injuries of the Talus Diagnosed by Bone Scan and Tomography

Foot & Ankle ◽  
1984 ◽  
Vol 4 (6) ◽  
pp. 316-324 ◽  
Author(s):  
J.K. Burkus ◽  
E.J. Sella ◽  
W.O. Southwick
Keyword(s):  
Diagnostic Tool ◽  
Bone Scan ◽  
Osteochondral Lesion ◽  
Bone Scanning ◽  
Average Delay ◽  
Plain Radiographs ◽  
X Ray ◽  
Bone Scans ◽  
Ankle And Foot

Five patients, four women and one man, were found to have an osteochondral lesion of one of the talar joints. All patients had normal plain radiographs of the ankle and foot and were referred to us as a second or third consultation for undiagnosed ankle and hindfoot pain. Bone scans of the tali demonstrated the specific talar joint that was injured, and tomography confirmed the presence of an osteochondral lesion. The average delay in the diagnosis between the onset of symptoms and the initiation of treatment was over 10 months. Bone scanning is an effective diagnostic tool in locating injuries of the talus not appreciated on routine x-ray.

scholarly journals 99mTc HMDP bone scanning in generalised nodal osteoarthritis. II. The four hour bone scan image predicts radiographic change.

1986 ◽  
Vol 45 (8) ◽  
pp. 622-626 ◽  
Author(s):  
C W Hutton ◽  
E R Higgs ◽  
P C Jackson ◽  
I Watt ◽  
P A Dieppe
Keyword(s):  
Bone Scan ◽  
Bone Scanning ◽  
Radiographic Change

The Bone Scan in Clinical Practice

1980 ◽  
Vol 25 (1) ◽  
pp. 45-49 ◽  
Author(s):  
I. Fogelman ◽  
I. T. Boyle
Keyword(s):  
Clinical Practice ◽  
Bone Scan ◽  
Clinical Importance ◽  
Relative Sensitivity ◽  
New Method ◽  
Bone Scanning ◽  
Technetium 99M ◽  
Bone Uptake

Radioisotopic bone scanning using technetium-99m labelled phosphate and diphosphonate compounds is a relatively new method of imaging the skeleton which has rapidly assumed major clinical importance. In this review the pathophysiology of bone uptake of radiopharmaceutical, the relative sensitivity of bone scan and radiograph, and the more important uses of bone scanning in clinical practice are described.

329: When to Perform a Bone Scan in Patients with Prostate Cancer. A novel Nomogram

2007 ◽  
Vol 177 (4S) ◽  
pp. 111-112
Author(s):  
Alberto Briganti ◽  
Tommaso C. Camerota ◽  
Firas Abdollah ◽  
Felix K.-H. Chun ◽  
Andrea Salonia ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Bone Scan

Decisive Diagnosis of Infected Mandibular Osteoradionecrosis with a Tc-99m-labelled Anti-granulocyte Fab′-fragment

1999 ◽  
Vol 38 (07) ◽  
pp. 309-311 ◽  
Author(s):  
W. Brenner ◽  
H. Terheyden ◽  
K. H. Bohuslavizki ◽  
E. Henze ◽  
W. U. Kampen
Keyword(s):  
Blood Pool ◽  
Bone Scanning ◽  
Acute Osteomyelitis ◽  
Elevated Blood ◽  
Fab Fragment ◽  
Postoperative Changes ◽  
Three Phase ◽  
Golden Standard ◽  
Blood Pool Activity ◽  
Bone Inflammation

SummaryThe accepted golden standard for detection of inflammatory bone disease is conventional three-phase bone scanning. Hyperperfusion, a high blood-pool activity and elevated bone metabolism are typical signs for an acute osteomyelitis. However, in case of subacute, chronic inflammation, neither elevated blood flow nor high blood-pool activity may be seen. This may cause difficulties in differentiating such cases from neoplastic or postoperative changes. This case report verifies the possible advantage of immunoscintigraphy with Tc-99m-labelled antigranulocyte Fab′-fragments (LeukoScan®) in a patient with infected mandibular osteoradionecrosis, who had equivocal clinical symptomes and questionable radiographic results. LeukoScan® is shown to be more sensitive in case of subacute bone inflammation compared with three-phase bone scanning. However, acquisition of delayed images after 24 hours including SPECT is inevitable in case of negative scans during the first hours of investigation.

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