scholarly journals Whole body bone mineral content in healthy children and adolescents

1997 ◽  
Vol 76 (1) ◽  
pp. 9-15 ◽  
Author(s):  
C. Molgaard ◽  
B. L. Thomsen ◽  
A. Prentice ◽  
T. J Cole ◽  
K. F. Michaelsen
Keyword(s):  
Bone Mineral Content ◽  
Children And Adolescents ◽  
Bone Mineral ◽  
Mineral Content ◽  
Whole Body ◽  
Healthy Children ◽  
Body Bone

scholarly journals Whole body bone mineral content in healthy children and adolescents

1998 ◽  
Vol 78 (4) ◽  
pp. 395-395 ◽  
Author(s):  
W J HANNAN ◽  
P TOTHILL ◽  
S J COWEN ◽  
R M WRATE
Keyword(s):  
Bone Mineral Content ◽  
Children And Adolescents ◽  
Bone Mineral ◽  
Mineral Content ◽  
Whole Body ◽  
Healthy Children ◽  
Body Bone

scholarly journals Whole body bone mineral accretion in healthy children and adolescents

1999 ◽  
Vol 81 (1) ◽  
pp. 10-15 ◽  
Author(s):  
C. Molgaard ◽  
B. L. Thomsen ◽  
K. F. Michaelsen
Keyword(s):  
Children And Adolescents ◽  
Bone Mineral ◽  
Whole Body ◽  
Healthy Children ◽  
Body Bone

scholarly journals Diabetes during Pregnancy Does Not Alter Whole Body Bone Mineral Content in Infants

1997 ◽  
Vol 82 (12) ◽  
pp. 3993-3997 ◽  
Author(s):  
Alexandre Lapillonne ◽  
Sophie Guerin ◽  
Pierre Braillon ◽  
Olivier Claris ◽  
Pierre D. Delmas ◽  
...  
Keyword(s):  
Birth Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Gestational Age ◽  
Mineral Content ◽  
Whole Body ◽  
X Ray ◽  
Diabetic Mothers ◽  
Body Bone

A previous study using single photon absorptiometry has reported low bone mineral density of the radius in infants of diabetic mothers. The aim of this study was to assess by dual x-ray absorptiometry the whole body bone mineral content (WbBMC) and the body composition of 40 infants of diabetic mothers at birth (mean gestational age ± sd, 37.5 ± 1.3 weeks; mean birth weight ± sd, 3815 ± 641 g). WbBMC was not correlated with gestational age, but was well correlated with birth weight (r = 0.73; P = 0.0001) and also with fat mass (r = 0.87; P = 0.0001) and lean mass (r = 0.42; P = 0.008). The z-scores ± sd adjusted for weight for WbBMC and fat mass were significantly increased (1.3 ± 0.9 and 2.6 ± 1.3, respectively (P < 0.0001), but were not significantly influenced either by in utero growth or by the type of the diabetes mellitus of the mother. Bone mineralization and fat mass studied by whole body dual x-ray absorptiometry are increased at birth in these infants compared with reference curves.

scholarly journals Daily Treatment with Human Recombinant Parathyroid Hormone-(1–34), LY333334, for 1 Year Increases Bone Mass in Ovariectomized Monkeys*

1999 ◽  
Vol 84 (10) ◽  
pp. 3757-3763 ◽  
Author(s):  
Robert Brommage ◽  
Charlotte E. Hotchkiss ◽  
Cynthia J. Lees ◽  
Melanie W. Stancill ◽  
Janet M. Hock ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Proximal Tibia ◽  
Whole Body ◽  
Mineral Density ◽  
Increase Bone Mass ◽  
Skeletal Effects ◽  
Body Bone

AbstractPTH stimulates bone formation to increase bone mass and strength in rats and humans. The aim of this study was to determine the skeletal effects of recombinant human PTH-(1–34) [rhPTH-(1–34)] in monkeys, as monkey bone remodeling and structure are similar to those in human bone.Adult female cynomolgus monkeys were divided into sham-vehicle (n= 21), ovariectomized (OVX)-vehicle (n = 20), and OVX groups given daily sc injections of rhPTH-(1–34) at 1 (n = 39) or 5 (n = 41) μg/kg for 12 months. Whole body bone mineral content was measured, as was bone mineral density (BMD) in the spine, proximal tibia, midshaft radius, and distal radius. Serum and urine samples were also analyzed. rhPTH-(1–34) treatment did not influence serum ionized Ca levels or urinary Ca excretion, but depressed endogenous PTH while increasing serum calcitriol levels. Compared to that in the OVX group, the higher dose of rhPTH-(1–34) increased spine BMD by 14.3%, whole body bone mineral content by 8.6%, and proximal tibia BMD by 10.8%. Subregion analyses suggested that the anabolic effect of rhPTH-(1–34) on the proximal tibia was primarily in cancellous bone. Similar, but less dramatic, effects on BMD were observed with the lower dose of rhPTH-(1–34). Daily sc rhPTH-(1–34) treatment for 1 yr increases BMD in ovariectomized monkeys without inducing sustained hypercalcemia or hypercalciuria.

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