Chronic autoimmune thyroiditis in children and adolescents: at presentation and during long-term follow-up

2009 ◽  
Vol 94 (1) ◽  
pp. 33-37 ◽  
Author(s):  
L de Vries ◽  
S Bulvik ◽  
M Phillip
Keyword(s):  
Children And Adolescents ◽  
Autoimmune Thyroiditis ◽  
Chronic Autoimmune Thyroiditis ◽  
Long Term Follow Up

Long-term follow-up of differentiated thyroid carcinoma in children and adolescents

2020 ◽  
Vol 33 (11) ◽  
pp. 1431-1441
Author(s):  
Montserrat Negre Busó ◽  
Amparo García Burillo ◽  
Marc Simó Perdigó ◽  
Pere Galofré Mora ◽  
Maria Boronat de Ferrater ◽  
...  
Keyword(s):  
Complete Remission ◽  
Thyroid Carcinoma ◽  
Children And Adolescents ◽  
Differentiated Thyroid Carcinoma ◽  
Radioiodine Treatment ◽  
Persistent Disease ◽  
Stage 4 ◽  
Long Term Follow Up

AbstractObjectivesThe aims were to analyze the clinical features, response to treatment, prognostic factors and long-term follow-up of children and adolescents with differentiated thyroid carcinoma (DTC).MethodsEighty patients with DTC were studied retrospectively. All underwent total or near-total thyroidectomy, and in 75 cases, ablative iodine therapy was recommended. Patients were assessed periodically by tests for serum thyroglobulin levels and whole-body iodine scans. Age, gender, initial clinical presentation, histology, tumor stage, postoperative complications, radioiodine treatment protocol, treatment response, thyroglobulin (Tg), recurrence and long-term disease progression were evaluated.ResultsSeventy patients completed >2 years of follow-up (23 males, 47 females; median age: 14 years; range: 3–18 years). Sixty-two patients showed papillary DTC and eight, follicular DTC. Sixty-five percent presented nodal metastasis and 16%, pulmonary metastasis at diagnosis. Six months after first radioiodine treatment, 36.2% of patients were free of disease. Seven recurrences were documented. At the end of follow-up, overall survival was 100%, and 87.2% of patients were in complete remission. Nine patients had persistent disease. We found a significant association between stage 4 and persistent disease. Hundred percent of patients with negative Tg values at 6 months posttreatment were documented free of disease at the end of the follow-up. The analysis of disease-free survival based on radioiodine treatment protocols used showed no statistically significant differences.ConclusionsDTC in children and adolescents is frequently associated with presence of advanced disease at diagnosis. Despite this, complete remission was documented after treatment in most cases, with a good prognosis in the long-term follow-up. Negative posttreatment thyroglobulin and stage 4 at diagnosis were significant prognostic variables.

A Long-Term Follow-Up Study on Endoscopic Management of Children and Adolescents With Chronic Pancreatitis

2010 ◽  
Vol 105 (8) ◽  
pp. 1884-1892 ◽  
Author(s):  
Zhao-Shen Li ◽  
Wei Wang ◽  
Zhuan Liao ◽  
Duo-Wu Zou ◽  
Zhen-Dong Jin ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Children And Adolescents ◽  
Endoscopic Management ◽  
Follow Up Study ◽  
Long Term Follow Up

scholarly journals Prolactinomas in Children and Adolescents. Clinical Presentation and Long-Term Follow-Up

1998 ◽  
Vol 83 (8) ◽  
pp. 2777-2780 ◽  
Author(s):  
Annamaria Colao ◽  
Sandro Loche ◽  
Marco Cappa ◽  
Antonella Di Sarno ◽  
Maria Luisa Landi ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Clinical Presentation ◽  
Long Term Follow Up
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