scholarly journals Infant feeding in the second 6 months of life related to iron status: an observational study

2007 ◽  
Vol 92 (10) ◽  
pp. 850-854 ◽  
Author(s):  
D. Hopkins ◽  
P. Emmett ◽  
C. Steer ◽  
I. Rogers ◽  
S. Noble ◽  
...  
2021 ◽  
Author(s):  
Rachael Taylor ◽  
Cathryn Conlon ◽  
Kathryn Beck ◽  
Pamela von Hurst ◽  
Lisa Te Morenga ◽  
...  

BACKGROUND The complementary feeding period is a time of unparalleled dietary change for every human, during which the diet changes from one that is 100% milk to a diet that resembles that of the wider family, in less than a year. Despite this major dietary shift, we know relatively little about food and nutrient intake in infants worldwide, and virtually nothing about the impact of baby food ‘pouches’ and ‘Baby-Led Weaning’ (BLW); infant feeding approaches that are becoming increasingly popular. Pouches are squeezable containers with a plastic spout that have great appeal for parents, as evidenced by their extraordinary market share worldwide. Baby-Led Weaning is an alternative approach to introducing solids that promotes the infant self-feeding whole foods rather than being fed purées, and is popular and widely advocated on social media. The nutritional and health impacts of these novel methods of infant feeding have not yet been determined. OBJECTIVE The aim of the First Foods New Zealand study is to determine the iron status, growth, food and nutrient intakes, breast milk intake, eating and feeding behaviours, dental health, oral motor skills, and choking risk, of New Zealand infants in general, and of those using pouches or BLW compared to those who are not. METHODS Dietary intake (two 24-hour recalls supplemented with food photographs), iron status (haemoglobin, plasma ferritin, soluble transferrin receptor), weight status (body mass index), food pouch use and extent of BLW (questionnaire), breast milk intake (deuterium oxide ‘dose-to-mother’ technique), eating and feeding behaviours (questionnaires and video recording of an evening meal), dental health (photographs of upper and lower teeth for counting of caries and developmental defects of enamel), oral motor skills (questionnaires), and choking risk (questionnaire) will be assessed in 625 infants aged 7.0-9.9 months. Propensity score matching will be used to address bias caused by differences in demographics between groups so that the results more closely represent a potential causal effect. RESULTS This observational study has full ethical approval from the Health and Disability Ethics Committees New Zealand (19/STH/151) and was funded in May 2019 by the Health Research Council (HRC) of New Zealand (grant 19/172). Data collection commenced in July 2020 and first results are expected to be submitted for publication in 2022. CONCLUSIONS This large study will provide much needed data on the implications for nutritional intake and health of the use of baby food pouches, and BLW, in infancy. CLINICALTRIAL Australian New Zealand Clinical Trials Registry (www.anzctr.org.au, registration number: ACTRN12620000459921).


10.2196/29048 ◽  
2021 ◽  
Author(s):  
Rachael Taylor ◽  
Cathryn Conlon ◽  
Kathryn Beck ◽  
Pamela von Hurst ◽  
Lisa Te Morenga ◽  
...  

2008 ◽  
Vol 121 (5) ◽  
pp. 392-398 ◽  
Author(s):  
Yu-hua GONG ◽  
Cheng-ye JI ◽  
Xiu-xia ZHENG ◽  
Jin-ping SHAN ◽  
Rui HOU

PEDIATRICS ◽  
1983 ◽  
Vol 72 (1) ◽  
pp. 33-36
Author(s):  
P. David Sadowitz ◽  
Frank A. Oski

The relationship of infant feeding practices to iron status was examined in a group of 280 infants, 9 to 12 months of age, attending a "well-baby" clinic. Of this group, 7.6% were found to be iron depleted, 19.7% were iron deficient without anemia, and 8.2% were iron deficient with anemia. The incidence of iron-deficiency anemia was significantly greater in the black infants than the white infants (14.3% v 2.7%). The introduction of whole cow's milk into the diet had occurred prior to 6 months of age in 29.2% of the infants, and 62.1% of these infants had laboratory evidence of nutritional iron inadequacy, as contrasted with only 21.8% of those with iron deficiencies fed cow's milk after 6 months of age. Of the 21 infants with iron-deficiency anemia, 19 (90.5%) had been fed whole cow's milk prior to 6 months of age. Iron deficiency remains a nutritional problem for infants in an urban setting and is largely a result of the early introduction of whole cow's milk into the diet.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Rachel M. Burke ◽  
Paulina A. Rebolledo ◽  
Anna M. Aceituno ◽  
Rita Revollo ◽  
Volga Iñiguez ◽  
...  

2015 ◽  
Vol 3 (6) ◽  
pp. 547-553
Author(s):  
Dr Yogendra Singh Yadav ◽  
◽  
Dr Sonali Yadav ◽  
Dr Sunil Rathi ◽  
Dr Mamta Dhaneria ◽  
...  

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 4001-4001 ◽  
Author(s):  
Irina Voronina ◽  
Mario Ojeda-Urib ◽  
Charles Dauriac ◽  
Laurent Voillat ◽  
Camille Aubron-Olivier ◽  
...  

Abstract Background: OncoBOS is a national, prospective, non-interventional, longitudinal, observational study describing biosimilar epoetin alfa (Binocrit®) use in routine practice in France in patients receiving chemotherapy treatment (CT) for solid tumors, lymphoma or myeloma. This sub-analysis focuses on the management of CIA in patients with MM. Patients and methods: Patients ≥18 years with MM, CIA and eligible for treatment with Binocrit® were included in this analysis. Patients characteristics, data on CIA and its management and predominant factors considered by the physician in prescribing Binocrit® were recorded at baseline, 3-4 weeks and 12 (± 1) weeks later. Hemoglobin (Hb) outcomes assessed included the proportion of patients achieving a Hb increase ≥1 and ≥2 g/dL, and the mean Hb change from baseline. Results: 99 patients with MM (mean age 71.1 years) from 20 sites were recruited from September 2011 to April 2014. 54.5% of subjects were male. Mean and median baseline Hb levels were 9.4 g/dL and 10 g/dL, respectively. The mean increase in Hb level was 1.1 g/dL after 1 month and 2.2 g/dL after 3 months (p<0.001 vs baseline) of Binocrit® treatment. A Hb increase ≥1 g/dL was achieved by 57.6% of patients at week 3-4 and 78.0% at week 12; a Hb increase ≥2 g/dL was achieved by 22.2% and 60.4% of patients at the same time points. Patients received a median dose of 30,000 IU Binocrit® once weekly. Four of the 99 patients (4.0%) required a dose increase; 3 of these patients had their dose doubled during the treatment period. Transfusion rates remained stable at 12.1% and 9.6% at week 3-4 and week 12, respectively. Oral and intravenous (IV) iron supplementation rates were low: oral iron was received by 1.0% and 2.2% of patients at week 3-4 and week 12, respectively; 1.0% and 1.1% of patients received IV supplementation at the same time points. Of note, these low rates could be explained by the fact that iron status (serum ferritin and transferrin saturation coefficient) was assessed in only 32.3% of subjects at baseline. Physicians considered quality of life (59.6%), fatigue (20.2%) and avoidance of blood transfusion (13.1%) as predominant factors in the rationale for anemia management and treatment. Over the treatment period, one treatment-related adverse reaction was recorded, which was not considered serious. Conclusion: This sub-analysis indicates that Binocrit®, used in routine practice, is effective and well tolerated for the treatment of CIA in patients with MM receiving CT. Disclosures Voronina: Sandoz: Investigator Other. Ojeda-Urib:Sandoz: Honoraria. Dauriac:Sandoz: Investigator Other. Voillat:Sandoz: Investigator Other. Aubron-Olivier:Sandoz: Employment. Fernet:Sandoz: Employment. Karlin:Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees; Sandoz: Honoraria, Membership on an entity's Board of Directors or advisory committees. Fitoussi:Sandoz: Honoraria.


2006 ◽  
Vol 67 (2) ◽  
pp. 72-76 ◽  
Author(s):  
France M. Rioux ◽  
Nadya Savoie ◽  
Jacques Allard

Purpose: Factors associated with early cessation of breastfeeding were identified and patterns of infant feeding were examined. Feeding practices were compared with the 1998 guidelines in Nutrition for Healthy Term Infants and with recent Health Canada recommendations. Methods: To recruit participants, a letter was sent to every mother (n=424) who gave birth at Dr. Georges-L. Dumont Regional Hospital in Moncton from April 1998 to February 1999. Eighty-five mothers agreed to participate with their infants. Information on infant feeding patterns and socioeconomic background was gathered with semi-structured questionnaires. Only healthy infants from singleton pregnancies were included in this study. Results: At birth, almost 83% of infants were breastfed. The proportions of infants breastfed for at least four, six, and nine months were 43%, 22%, and 9%, respectively. As many as 34% of infants were introduced to baby cereals before age four months, and 21% were introduced to cow’s milk before age nine months. Lower family income, lower level of parental education, and reduced postpartum hemoglobin level (below 95 g/L) were associated with discontinuation of breastfeeding before infants were four months old. Conclusions: Early postpartum nutrition interventions may be effective in ensuring follow-up care for mothers with compromised iron status, in supporting breastfeeding for at least six months, and in promoting better infant feeding practices.


2021 ◽  
Author(s):  
Chayatat Ruangkit ◽  
Nawapat Prachakittikul ◽  
Nutthida Hemprachitchai ◽  
Oraporn Dumrongwongsiri ◽  
Sasivimon Soonsawad

Abstract Background: An infant's iron intake in the first 6 months of life comes solely from milk intake. However, infants' feeding practices vary, and their association with infants' iron status and hematologic parameters has not been well studied. We aimed to evaluate how different infant feeding practices associate with iron status and hematologic parameters among 6-month-old Thai infants. Methods: In a retrospective chart review, we identified 403 infants who attended a well-baby clinic and received laboratory screening for anemia (complete blood count and serum ferritin) at 6-month visits. Infants were categorized into four groups according to feeding practices. Hematologic parameters and incidence of anemia (hemoglobin [Hb]<11 g/dL), iron deficiency (ID; ferritin<12 ng/mL), and iron deficiency anemia (IDA; Hb<11 g/dL and ferritin<12 ng/mL) were compared between groups. Univariate and multiple logistic regression models were used to identify IDA associated factors among 6-month-old infants. Results: In total, 105 infants were breastfed (BF), 78 were breastfed with iron supplementation (BI), 109 infants were mixed-fed (breast milk and formula) with or without iron supplementation starting at age 4 months (MF), and 111 infants were formula-fed (FF). The BF group had the highest incidence of anemia, ID, and IDA. Anemia was found in 38.1% of BF infants compared with 21.8% of BI, 19.3% of MF, and 16.2% of FF infants (p<0.001). ID was found in 28.6% of BF infants compared with 3.8% of BI, 3.7% of MF, and 0.9% of FF infants (p<0.001). IDA was found in 17.1% of BF infants compared with 2.6% of BI, 0.9% of MF, and 0.9% of FF infants (p<0.001). In multivariate logistic regression, higher weight gain during 0–6 months slightly increased the risk of IDA and higher birth weight slightly decreased this risk. BI, MF, and FF infants had 90.4%, 97.5%, and 96.9% decreased risk of IDA, respectively, with BF infants as a reference group. Conclusion: The incidence of anemia, ID, and IDA at age 6 months was higher in BF than FF or partially BF infants. However, iron supplements in BF infants starting at 4 months significantly reduced their ID and IDA incidence.


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