Microwave-assisted solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by NH4OBr

2011 ◽  
Vol 76 (8) ◽  
pp. 989-995 ◽  
Author(s):  
Davood Azarifar ◽  
Kaveh Khosravi ◽  
Khadijeh Soleimani ◽  
Zohreh Najminejad
Keyword(s):  
Condensation Reaction ◽  
Solvent Free ◽  
Conventional Heating ◽  
One Pot ◽  
Keto Ester ◽  
Microwave Assisted ◽  
Catalytic Potential ◽  
Reaction Proceeds ◽  
The One ◽  
Solvent Free Synthesis

Catalytic potential of ammonium hypobromite in the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones from Biginelli-type condensation reaction between an aldehyde, β-keto ester and urea has been explored. The reaction proceeds under solvent-free conventional heating as well as microwave-irradiation conditions to afford the respective products in excellent yields.

ChemInform Abstract: An Efficient One-Pot and Solvent-Free Synthesis of Chromeno[2,3-d]pyrimidine Derivatives: Microwave Assisted Reaction.

ChemInform ◽  
2010 ◽  
Vol 41 (40) ◽  
pp. no-no
Author(s):  
Afsaneh Zonouzi ◽  
Mojtaba Biniaz ◽  
Roghieh Mirzazadeh ◽  
Merzieh Talebi ◽  
Seik Weng Ng
Keyword(s):  
Solvent Free ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Microwave Assisted ◽  
Solvent Free Synthesis

scholarly journals Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Fatemeh Janati ◽  
Majid M. Heravi ◽  
Ahmad Mirshokraie
Keyword(s):  
Iron Oxide ◽  
Superparamagnetic Iron Oxide ◽  
Solvent Free ◽  
One Pot ◽  
Efficient Catalyst ◽  
External Magnet ◽  
The One ◽  
Short Time ◽  
Solvent Free Synthesis

Superparamagnetic Fe3O4is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of 5,5-disubstituted hexahydropyrimidines and their spiropiperidines. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeable loss of activity. The products are obtained in short time and good purity upon separation of the catalyst and evaporation of the volatiles of the reaction mixture.

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