Voltammetric Determination of Mitomycin c Using a Chemically-Modified Glassy Carbon Electrode

2005 ◽  
Vol 70 (2) ◽  
pp. 178-187 ◽  
Author(s):  
Wanyun Qu ◽  
Hong Wang ◽  
Kangbing Wu
Keyword(s):  
Mitomycin C ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Low Cost ◽  
Direct Determination ◽  
High Sensitivity ◽  
Carbon Electrode ◽  
Oxidation Peak

An electrochemical method for the direct determination of mitomycin c (MMC), based on a multi wall carbon nanotube (MWNT)-modified electrode, has been developed. A well-shaped and highly sensitive oxidation peak at 0.79 V was observed on the MWNT-modified electrode for MMC. Further studies show strong evidence that MWNT-modified electrode significantly enhances the sensitivity of determination of MMC since the oxidation peak current of MMC increases remarkably, compared with that with a bare glassy carbon electrode. All the experimental parameters such as pH, scan rate, accumulation conditions, have been examined. A sensitive linear voltammetric response for MMC was obtained over the concentration range of 2.5 × 10-7-1.0 × 10-4 mol/l; the detection limit is 8 × 10-8 mol/l. Compared with other methods, this new-proposed method possesses advantages such as high sensitivity, fast response, low cost and simplicity. Eventually, the proposed method has been successfully employed to detect MMC in urine samples.

Self-Assembled Graphene for Determination of Catechol in Wastewater at Modified Glassy Carbon Electrode

2012 ◽  
Vol 161 ◽  
pp. 255-259 ◽  
Author(s):  
Mei Feng Chen ◽  
Xin Ying Ma ◽  
Xia Li
Keyword(s):  
Cyclic Voltammetry ◽  
Detection Limit ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
High Sensitivity ◽  
Carbon Electrode ◽  
Oxidation Peak ◽  
Modified Glassy Carbon Electrode

Graphene-modified glassy carbon electrode was made by dropping. In phosphate-citric acid buffered saline, the modified electrode was shown to possess an excellent selective electrocatalytical effect on the redox of catechol, and further used to determine catechol in the presence of resorcin and hydroquinone by cyclic voltammetry. The oxidation peak currents Ipa showed a linear relationship with the concentrations (c) of catechol in the range of 2.97×10-7 mol•L-1~9.31×10-6 mol•L-1 and 9.31×10-6 mol•L-1~1.03×10-4 mol•L-1 with a correlation coefficient as follows: Ipa1(A)= -4.10×10-6-2.31c, R=0.Superscript text9971; Ipa2 (A) =-1.50×10-5-0.60c, R=0.9953, respectively, and the detection limit is 2.50×10-8 mol•L-1. The modified electrode is high sensitivity, selectivity, stability, and has been successfulSuperscript textly applied to analyzing catechol in wastewater.

Electrocatalytic Property Toward Dopamine and Uric Acid of the Nanoparticles TiO2 Modified Electrode

2013 ◽  
Vol 785-786 ◽  
pp. 508-511
Author(s):  
Ying Zhang ◽  
Guo Bao Li ◽  
Qiu Xia Yang
Keyword(s):  
Uric Acid ◽  
Linear Relationship ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Differential Pulse ◽  
Carbon Electrode ◽  
Oxidation Peak ◽  
Good Electrocatalytic Activity

The titanium sol was prepared by depositing the organic titanium on glassy carbon electrode surface. Electrophoresis time and the applied voltage as well can markedly influence the electrochemical behavior of the nanoTiO2film. In contrast with bare glassy carbon electrode, the nanoTiO2film on glassy carbon electrode had a good electrocatalytic activity to dopamine (DA) and uric acid (UA) in PBS solution. The result showed that there was a linear relationship between the oxidation peak currents and the concentration of DA from 8.0×10-6to 4.0×10-4mol·L-1by differential pulse voltammetry (DPV) and there was a linear relationship between the oxidation peak currents and the concentration of UA from 8×10-6to 1.0×10-3mol·L-1. This modified electrode was quite effective to detect DA and UA in simultaneous determination of these species in a mixture.

scholarly journals Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Abd-Elgawad Radi ◽  
Nadia Abd El-Ghany ◽  
Tarek Wahdan
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Direct Determination ◽  
High Sensitivity ◽  
Raw Milk ◽  
Differential Pulse ◽  
Electrochemical Sensing ◽  
Carbon Electrode ◽  
Molecularly Imprinted

A novel electrochemical sensing approach, based on electropolymerization of a molecularly imprinted polypyrrole (MIPpy) film onto a glassy carbon electrode (GCE) surface, was developed for the detection of flunixin (FXN). The sensing conditions and the performance of the constructed sensor were assessed by cyclic, differential pulse and (DPV) square wave voltammetry (SWV). The sensor exhibited high sensitivity, with linear responses in the range of 5.0 to 50.0 µM with detection limits of 1.5 and 1.0 µM for DPV and SWV, respectively. In addition, the sensor showed high selectivity towards FXN in comparison to other interferents. The sensor was successfully utilized for the direct determination of FXN in buffalo raw milk samples.

Amperometric determination of NADH based on a poly-Ni(ii)–curcumin composite film modified glassy carbon electrode

2014 ◽  
Vol 6 (18) ◽  
pp. 7496-7501 ◽  
Author(s):  
Xiaoqian Ouyang ◽  
Yaping Ding ◽  
Xi Ba ◽  
Shuqing Gu
Keyword(s):  
Composite Film ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Amperometric Detection ◽  
High Sensitivity ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Amperometric Determination

A poly-Ni(ii)–curcumin composite film modified electrode was prepared for amperometric detection of NADH with high sensitivity.

scholarly journals Electrochemical determination of ascorbic acid at p-phenylenediamine film-holes modified glassy carbon electrode

2015 ◽  
Vol 80 (9) ◽  
pp. 1161-1175 ◽  
Author(s):  
Bikila Olana ◽  
Shimeles Kitte ◽  
Tesfaye Soreta
Keyword(s):  
Ascorbic Acid ◽  
Detection Limit ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Linear Response ◽  
Modified Electrodes ◽  
Electrochemical Determination ◽  
Carbon Electrode

In this work the determination of ascorbic acid (AA) at glassy carbon electrode (GCE) modified with a perforated film produced by reduction of diazonium generated in situ from p-phenylenediamine (PD) is reported. Holes were intentionally created in the modifier film by stripping a pre-deposited gold nanoparticles. The modified electrodes were electrochemically characterized by common redox probes: hydroquinone, ferrocyanide and hexamineruthenium(III). The cyclic voltammetric and amperometric response of AA using the modified electrodes was compared with that of bare GCE. The bare GCE showed a linear response to AA in the concentration range of 5 mM to 45 mM with detection limit of 1.656 mM and the modified GCE showed a linear response to AA in the concentration range of 5 ?M to 45 ?M with detection limit of 0.123 ?M. The effect of potential intereferents on amperometric signal of AA at the modified GCE was examined and found to be minimal. The inter-electrode reproducibility, stability, and accuracy were determined. The modified electrode showed excellent inter-electrode reproducibility, accuracy and stability. The modified electrode reported is a promising candidate for use in electroanalysis of AA.

scholarly journals Electrochemical Determination of Trace Pb (II) by The Modified Glassy Carbon Electrode Compositing MultiWalled Carbon Nanotubes-Nafion-Bi Film

2020 ◽  
pp. 1-12
Keyword(s):  
Carbon Nanotubes ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Anodic Stripping Voltammetry ◽  
Electrochemical Sensing ◽  
Carbon Electrode ◽  
Bismuth Film ◽  
Modified Glassy Carbon Electrode

A modified glassy carbon electrode (GCE) compositing multi-walled carbon nanotubes (MWCNTs), Nafion and bismuth film was prepared and applied for the sensitive detection of trace Pb (II). MWCNTs were dispersed into ethanol by ultrasonication in the presence of Nafion and the nanotubes are coated onto the bare GCE. After that, an extra Nafion adhesion agent is added to the electrode. By the in situ plating, a bismuth film was fabricated on the MWCNTs-NA/GCE, making the desired electrode, MWCNTs-NA-Bi/GCE. The modified electrode was characterized by differential pulse anodic stripping voltammetry, scanning electron microscopy, and cyclic voltammetry. A deposition potential of –1.4 V (vs. Ag/AgCl) and a deposition time of 300 s were applied to the working electrode under stirred conditions after optimizing. Nanotubes and Nafion concentrations and pH were carefully optimized to determine trace lead ions by using the electrode as an electrochemical-sensing platform. Nafion effectively increased the stability and adhesivity of the composite film. The MWCNTs-NA-Bi film modified electrode can remarkably increase the anodic peak current of Pb2+. The sensitivity of MWCNTs-NA-Bi/GCE is 4.35 times higher than that of the bare GCE with bismuth film. The prepared electrode showed excellent stability and reproducibility and can be applied for determination of Pb2+ contained wastewater.

scholarly journals Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Koh Sing Ngai ◽  
Wee Tee Tan ◽  
Zulkarnain Zainal ◽  
Ruzniza Mohd Zawawi ◽  
Joon Ching Juan
Keyword(s):  
Cyclic Voltammetry ◽  
Carbon Nanotube ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Single Walled Carbon Nanotube ◽  
Paracetamol Concentration ◽  
Single Walled Carbon

A rapid, simple, and sensitive method for the electrochemical determination of paracetamol was developed. A single-walled carbon nanotube/nickel (SWCNT/Ni) nanocomposite was prepared and immobilized on a glassy carbon electrode (GCE) surface via mechanical attachment. This paper reports the voltammetry study on the effect of paracetamol concentration, scan rate, pH, and temperature at a SWCNT/Ni-modified electrode in the determination of paracetamol. The characterization of the SWCNT/Ni/GCE was performed by cyclic voltammetry. Variable pressure scanning electron microscopy (VPSEM) and energy dispersive X-ray (EDX) spectrometer were used to examine the surface morphology and elemental profile of the modified electrode, respectively. Cyclic voltammetry showed significant enhancement in peak current for the determination of paracetamol at the SWCNT/Ni-modified electrode. A linear calibration curve was obtained for the paracetamol concentration between 0.05 and 0.50 mM. The SWCNT/Ni/GCE displayed a sensitivity of 64 mA M−1and a detection limit of 1.17 × 10−7 M in paracetamol detection. The proposed electrode can be applied for the determination of paracetamol in real pharmaceutical samples with satisfactory performance. Results indicate that electrodes modified with SWCNT and nickel nanoparticles exhibit better electrocatalytic activity towards paracetamol.

Simultaneous determination of TBHQ and BHA on a MWNT-Brij® 35 modified electrode in micellar media

2015 ◽  
Vol 7 (19) ◽  
pp. 8344-8351 ◽  
Author(s):  
Guzel Ziyatdinova ◽  
Karina Os'kina ◽  
Endzhe Ziganshina ◽  
Herman Budnikov
Keyword(s):  
Simultaneous Determination ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Micellar Medium ◽  
Micellar Media ◽  
Modified Glassy Carbon Electrode ◽  
Simultaneous Voltammetric Determination

Simultaneous voltammetric determination of TBHQ and BHA using a MWNT-Brij® 35 modified glassy carbon electrode in Brij® 35 micellar medium.

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