Disulfide tethered solid supports for oligonucleotide synthesis: Preparation and a comparative study on the resistance to ammonolysis

1996 ◽  
Vol 61 (s1) ◽  
pp. 110-111
Author(s):  
Harri Salo ◽  
Andrei Guzaev ◽  
Alex Azhayev ◽  
Harri Lönnberg
Keyword(s):  
Comparative Study ◽  
Oligonucleotide Synthesis ◽  
Solid Supports

Composite Magnetic and Non-magnetic Beads as Efficient Solid Supports for Machine-Aided Oligonucleotide Synthesis

2001 ◽  
Vol 84 (2) ◽  
pp. 345-350 ◽  
Author(s):  
Pradeep Kumar ◽  
Ashwani K. Sharma ◽  
Kailash C. Gupta ◽  
Shlomo Margel ◽  
Sigalit Gura ◽  
...  
Keyword(s):  
Magnetic Beads ◽  
Oligonucleotide Synthesis ◽  
Solid Supports

Comparative study of antigenic properties of potato virus X and its coat protein in solution and after adsorption to solid supports

1991 ◽  
Vol 32 (2-3) ◽  
pp. 317-326 ◽  
Author(s):  
E.N. Dobrov ◽  
A.F. Bobkova ◽  
M.I. Goldstein ◽  
E.K. Timofeeva ◽  
J.G. Atabekov
Keyword(s):  
Coat Protein ◽  
Comparative Study ◽  
Potato Virus ◽  
Potato Virus X ◽  
Solid Supports ◽  
Antigenic Properties

scholarly journals Oligonucleotide synthesis using the 2-(levulinyloxymethyl)-5-nitrobenzoyl group for the 5'-position of nucleoside 3'-phosphoramidite derivatives.

1998 ◽  
Vol 45 (4) ◽  
pp. 949-976 ◽  
Author(s):  
K Kamaike ◽  
H Takahashi ◽  
K Morohoshi ◽  
N Kataoka ◽  
T Kakinuma ◽  
...  
Keyword(s):  
Comparative Study ◽  
Protecting Groups ◽  
Protecting Group ◽  
Oligonucleotide Synthesis ◽  
Amino Groups ◽  
Initiator Trna ◽  
15N Labeling

A comparative study on the utility of 2-(levulinyloxymethyl)-5-nitrobenzoyl (LMNBz) and 2-(levulinyloxymethyl)benzoyl (LMBz) protecting groups for the 5'-positions of nucleoside 3'-phosphoramidite derivatives in the oligonucleotide synthesis is presented in terms of the syntheses of TpTpT, TpTpTpT, and UpCpApGpUpUpGpG. In addition we describe the synthesis, using the LMNBz protecting group, of the CpCpA terminus triplet of tRNAs bearing exocyclic amino groups with 15N-labeling, and the trimer Gp[A*]pG containing 2'-O-(beta-D-ribofuranosyl)adenosine ([A*]), the latter of which is found at position 64 in the yeast initiator tRNA(Met).

Versatile Solid Supports for Oligonucleotide Synthesis that Incorporate Urea Bridge

2011 ◽  
Vol 30 (7-8) ◽  
pp. 475-489 ◽  
Author(s):  
Andrey Yagodkin ◽  
Janne Weisel ◽  
Alex Azhayev
Keyword(s):  
Oligonucleotide Synthesis ◽  
Solid Supports

Automated chloridite and amidite synthesis of oligodeoxyribonucleotides on a long chain support using amidine protected purine nucleosides

1989 ◽  
Vol 54 (2) ◽  
pp. 523-532 ◽  
Author(s):  
Luboš Arnold ◽  
Zdeněk Točík ◽  
Eliška Bradková ◽  
Zdeněk Hostomský ◽  
Václav Pačes ◽  
...  
Keyword(s):  
Automated Synthesis ◽  
Oligonucleotide Synthesis ◽  
Potassium Salts ◽  
Solid Supports ◽  
Ethanol Precipitation ◽  
Aliphatic Spacer ◽  
Long Chain

Preparation of solid supports with long aliphatic spacer for the oligonucleotide synthesis is described. Automated synthesis of oligodeoxyribonucleotides using in situ prepared methylchlorophosphite intermediates from amidine protected purine nucleosides is described. Phosphoramidite synthesis of oligodeoxyribonucleotides mediated by 1-methylimidazole trifluoromethanesulfonate is described. Novel isolation of crude oligonucleotides by ethanol precipitation of potassium salts is described.

A direct and efficient method for derivatisation of solid supports for oligonucleotide synthesis

1997 ◽  
Vol 38 (9) ◽  
pp. 1651-1654 ◽  
Author(s):  
Andrew J. Walsh ◽  
G.Claudine Clark ◽  
William Fraser
Keyword(s):  
Efficient Method ◽  
Oligonucleotide Synthesis ◽  
Solid Supports
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