Solid-Phase Organic Synthesis: Creation of Carbon-Carbon Double Bonds Under Mild Conditions by Wittig-Type Reactions

1996 ◽  
Vol 61 (12) ◽  
pp. 1697-1702 ◽  
Author(s):  
Josef Vágner ◽  
Viktor Krchňák ◽  
Michal Lebl ◽  
George Barany
Keyword(s):  
Organic Synthesis ◽  
Solid Phase ◽  
Double Bonds ◽  
Mild Conditions ◽  
Solid Phase Organic Synthesis ◽  
Aldehydes And Ketones ◽  
Effective Conditions ◽  
Acid Labile

Phosphorane ylides and phosphonate anions react smoothly with resin-bound aldehydes and ketones to provide alkenes in good yields and purities (assessed after cleavage of acid-labile PAL anchor to support). The reactions of aldehydes give excellent stereoselectivities. Effective conditions have been developed for carrying out these transformations.

Recent Application of Polystyrene-supported Triphenylphosphine in Solid-Phase Organic Synthesis

2019 ◽  
Vol 23 (6) ◽  
pp. 643-678
Author(s):  
Lalthazuala Rokhum ◽  
Ghanashyam Bez
Keyword(s):  
Organic Synthesis ◽  
Combinatorial Chemistry ◽  
Solid Phase ◽  
Recent Application ◽  
Organic Transformations ◽  
Solid Phase Organic Synthesis ◽  
Wide Range ◽  
Fast Development ◽  
Polymer Supported

Recent years have witnessed a fast development of solid phase synthetic pathways, a variety of solid-supported reagent and its applications in diverse synthetic strategies and pharmaceutical applicability’s. Polymer-supported triphenylphosphine is getting a lot of applications owing to the speed and simplicity in the process. Furthermore, ease of recyclability and reuse of polymer-supported triphenylphosphine added its advantages. This review covers a wide range of useful organic transformations which are accomplished using cross-linked polystyrene-supported triphenylphosphine with the aim of giving renewed interest in the field of organic and medicinal-combinatorial chemistry.

Neutral Reducing Agents Supported on Merrifield Resin Obtained by Solid Phase Organic Synthesis

Tetrahedron ◽  
2021 ◽  
pp. 132195
Author(s):  
Milagros Aguilar-Martínez ◽  
Judas Tadeo Vargas-Durazo ◽  
Adrián Ochoa-Terán ◽  
Hisila Santacruz-Ortega ◽  
Karen Ochoa Lara ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Solid Phase ◽  
Reducing Agents ◽  
Solid Phase Organic Synthesis ◽  
Merrifield Resin

PhFl acetic acid: A new linker for solid phase organic synthesis

1998 ◽  
Vol 39 (26) ◽  
pp. 4591-4594 ◽  
Author(s):  
Konrad H. Bleicher ◽  
James R. Wareing
Keyword(s):  
Acetic Acid ◽  
Organic Synthesis ◽  
Solid Phase ◽  
Solid Phase Organic Synthesis

Solid Phase Organic Synthesis of Piperazinone Containing Enkephalin Mimetics:  A Readily Derivatized, Traceless Scaffold

1999 ◽  
Vol 1 (5) ◽  
pp. 383-387 ◽  
Author(s):  
Kevin Shreder ◽  
Li Zhang ◽  
Jean-Paul Gleeson ◽  
Jens A. Ericsson ◽  
Venkatachalapathi V. Yalamoori ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Solid Phase ◽  
Solid Phase Organic Synthesis

PhFl polystyrene: A new resin for solid phase organic synthesis

1998 ◽  
Vol 39 (26) ◽  
pp. 4587-4590 ◽  
Author(s):  
Konrad H. Bleicher ◽  
James R. Wareing
Keyword(s):  
Organic Synthesis ◽  
Solid Phase ◽  
Solid Phase Organic Synthesis

Perkin 1 Abstracts: Solid Phase Organic Synthesis

1999 ◽  
pp. xi-xiv
Author(s):  
John Christopher ◽  
Catherine McCusker ◽  
Susan Booth ◽  
Jason Tierney
Keyword(s):  
Organic Synthesis ◽  
Solid Phase ◽  
Solid Phase Organic Synthesis
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