Synthesis and Antibacterial Properties of Some 4-Amino Substituted 2-Phenyl-6H-5,1,3-benzothiadiazocines

1996 ◽  
Vol 61 (11) ◽  
pp. 1681-1688 ◽  
Author(s):  
Michal Bodajla ◽  
Štefan Stankovský ◽  
Katarína Špirková ◽  
Soňa Jantová
Keyword(s):  
Mass Spectra ◽  
Antibacterial Properties ◽  
H Nmr ◽  
Antibacterial Screening

Some 4-amino substituted 2-phenyl-6H-5,1,3-benzothiadiazocines (4a-4j) were prepared by cyclization of the corresponding N1-[N-(2-chloromethylphenyl)benzimidoyl]-N2-substituted thioureas (3a-3j). The IR,1H NMR and mass spectra of the title compounds are reported together with the results of antibacterial screening.

Synthesis of 2-amino-5,7-dimethyl-4-oxopyrido[3,4-e]-1,3-thiazines

1983 ◽  
Vol 48 (12) ◽  
pp. 3426-3432 ◽  
Author(s):  
Dušan Koščík ◽  
Pavol Kristian ◽  
Ondrej Forgáč
Keyword(s):  
Spectral Data ◽  
Chlorine Atom ◽  
Mass Spectra ◽  
High Reactivity ◽  
Secondary Amines ◽  
Dimroth Rearrangement ◽  
H Nmr ◽  
New Synthesis ◽  
C Nmr

New synthesis of pyrido[3,4-e]-1,3-thiazines consisting in reaction of 2,6-dimethyl-4-chloronicotinoyl isothiocyanate with primary or secondary amines, or with benzaldehyde phenylhydrazone, is described. High reactivity of the chlorine atom does not allow isolation of the corresponding thioureas, arising as intermediates, except in the case of the benzylamino derivative. Structure of the products was unequivocally confirmed by their spectral data (IR, UV, 1H NMR, 13C NMR and mass spectra). The synthesized derivatives do not undergo the Dimroth rearrangement.

Oxynemorensine, an alkaloid from Senecio nemorensis L., var. subdecurrens GRISEB

1980 ◽  
Vol 45 (2) ◽  
pp. 548-558 ◽  
Author(s):  
Antonín Klásek ◽  
Petr Sedmera ◽  
Jindřich Vokoun ◽  
Anna Boeva ◽  
Svatava Dvoráčková ◽  
...  
Keyword(s):  
Unsaturated Acid ◽  
Mass Spectra ◽  
H Nmr ◽  
C Nmr

From S. nemorensis L., var. subdecurrens GRISEB. there were isolated the previously obtained alkaloids nemorensine (I), retroisosenine (II), bulgarsenine (III) and, in addition, the alkaloid oxynemorensine which was assigned the structure VIII on the basis of the interpretation of the 1H-NMR, 13C-NMR, mass spectra, and on that of the identification of the products of hydrolysis and reduction. Furthermore, the isolation of the cis-nemorensic acid (V) as well as that of the unsaturated acid IV, and the transformation of bulgarsenine (III) to nemorensine (I) were described.

scholarly journals Isocyanate und verwandte Verbindungen des trimeren Phosphornitriddifluorids / Isocyanates and Related Compounds of Trimeric Phosphor-difluoronitride

1971 ◽  
Vol 26 (7) ◽  
pp. 679-683 ◽  
Author(s):  
Herbert W. Roesky ◽  
Enno Janssen
Keyword(s):  
Ir Spectra ◽  
Elemental Analysis ◽  
Mass Spectra ◽  
H Nmr ◽  
Carbonic Acids ◽  
Related Compounds

P3N3F5NCO was prepared by reaction of P3N3F5NSO with (COCl) 2. Substituted amides were obtained from the reaction of P3N3F5NSO with carbonic acids e. g. P3N3F5NHCOCH3, P3N3F5NHCOC2H5, and P3N3F5NHCOC3H7. If these substances were treated with PCl5 the following compounds P3N3F5N = CClCH3, P3N3F5N = CClCH5, and P3N3F5TN = CClC3H7 were formed. They reacted with nucleophiles to give P3N3F5N = CNH2CH3, P3N3F5N = TN (CH3) 2C2H5, and P3N3F5N = CN (CH3) 2CH7. The properties of these compounds are described. They were characterized by elemental analysis and IR-spectra. 19F-, 1H-NMR, and mass spectra are reported.

scholarly journals Metallkomplexe mit Tetrapyrrol-Liganden, XXXVIII [1]. Zur Kenntnis der Alkyl- und Arylimidovanadium(IV)-Porphyrine / Metal Complexes with Tetrapyrrole Ligands, XXXVIII [1]. On the Knowledge of Alkyl- and Arylimidovanadium(IV) Porphyrins

1985 ◽  
Vol 40 (10) ◽  
pp. 1362-1370 ◽  
Author(s):  
Johann W. Buchler ◽  
Stefan Pfeifer
Keyword(s):  
Mass Spectra ◽  
Nmr Spectra ◽  
Primary Amines ◽  
Reactive Intermediate ◽  
H Nmr ◽  
Vanadyl Complex ◽  
Elemental Analyses ◽  
Paramagnetic Metal ◽  
Paramagnetic Complexes ◽  
Proton Resonances

A series of novel alkyl or aryiimidovanadium(IV) 5,10,15,20-tetra(p-tolyl)porphyrinates, VNR(TTP) (4a-4g), is described. They are obtained from the vanadyl complex, VO(TTP) (2a) via the reactive intermediate VCl2(TTP) (3b) which undergoes aminolysis with the respective primary amines RNH2 (R = tBu, Ph, pTol, pClPh, pAnis, pBiph, ptBuPh)**. The formulae are proved by elemental analyses and mass spectra. The paramagnetic complexes are stable to water and may thus be purified by chromatography but are hydrolyzed to give 2 a on treatment with acetic acid. The UV/VIS and 1H NMR spectra of 4a-4g are of the same type as 2a, but the former are slightly hypsochromically shifted, and the latter do not show the proton resonances of the organylimide ligands due to the proximity of the paramagnetic metal center.

Phosphor- und Schwefelhydrazin-Verbindungen / Phosphorus- and Sulfurhydrazine-Compounds

1971 ◽  
Vol 26 (12) ◽  
pp. 1232-1235 ◽  
Author(s):  
Herbert W. Roesky ◽  
Olaf Petersen
Keyword(s):  
Ir Spectra ◽  
Elemental Analysis ◽  
Mass Spectra ◽  
Molar Ratio ◽  
H Nmr ◽  
Chemical Behaviour

Pyrosulfonyldifluoride reacts with waterfree hydrazine in a molar ratio of 2 : 3 to give hydrazine -1,2-bis(sulfonylfluoride) in a low yield.. The reaction of N-fluorosulfonylamide and SOCl2 yields NH4⊕⊖ N(SO2F)2. This salt is converted to (C6H5)4P⊕⊖N(SO2F)2 in water by (C6H5)4PCl. (CH3)2NNH2 reacts with PSF3, PSF2Br, PSF2CH3 or PSF2C2H5 to yield the following compounds: (CH3)2NNHPSF2, (CH3)2NN (PSF2)2, (CH3)2NNHPSFCH3 and (CH3)2NNHPSFC2H5. The properties and the chemical behaviour of these substances are described. Results of ir-spectra, as well as 31P-, 19F- and 1H-nmr- and mass-spectra and elemental analysis characterize the compounds.

scholarly journals Chemie polyfunktioneller Moleküle, 114 [1]. Synthese und Struktur eines ionischen und nichtionischen, cyclischen Carbaphosphazens und eines Cobalt(III)phosphazen-Komplexes / Chemistry of Polyfunctional Molecules, 114 [1]. Synthesis and Structure of an Ionic and Non Ionic Cyclic Carbaphosphazene and of a Cobalt(III)phosphazene Complex

1994 ◽  
Vol 49 (12) ◽  
pp. 1763-1773 ◽  
Author(s):  
Jochen Ellermann ◽  
Jörg Sutter ◽  
Falk A. Knoch ◽  
Matthias Moll ◽  
Walter Bauer
Keyword(s):  
Mass Spectra ◽  
Monoclinic Space Group ◽  
Triclinic Space Group ◽  
Space Group ◽  
X Ray ◽  
Lattice Constants ◽  
H Nmr

Reaction of (1) in CH2Cl2 with benzimidazole yields . The salt [4]+BPh4- has been prepared in THF by metathesis of [4]+Cl- with NaBPh4. Deprotonation of the cationic ring in [4]+BPh4- was accomplished using 1,8-diazabicyclo[5.4.01,7]undec-7-ene and resulted in the six-membered carbacyclophosphazene (6). Treating 1 with 8 -hydroxyquinoline in CH2Cl2 yields the octahedral cis-complex = 8-oxyquinolinate group). The com pounds [4]+BPh4-, 6 and 7 are characterized by their IR, Raman, 31P{1H} NMR, 13C{1H} NMR, 1H NMR and mass spectra. Crystals suitable for X-ray structure analyses have been obtained for [4]+BPh4- and 7×0.5 CH2Cl2. The colourless plates of [4]+BPh4- crystallize in the triclinic space group P1̄, with the lattice constants a = 1172.7(3), b = 1326.2(3), c = 1806.1(6) pm; α = 100.79(2), β = 103.71(3), γ = 108.18(2)°. The black blocks of 7×0.5 CH2Cl2 crystallize in the monoclinic space group P 21/c with the lattice constants a = 1159.0(10), b = 2008.9(10), c = 2034.6(12) pm; β = 105.86(5)°.

Notizen: Bis(trimethylsilylhydrazido)-thiophosphorsäurephenylester – ein neues Zwischenprodukt für die Synthese anorganischer Heterocyclen / Bis(trimethylsilylhydrazido)-thiophosphoric Acid Phenylester - A New Intermediate for the Synthesis of Inorganic Heterocycles

1975 ◽  
Vol 30 (7-8) ◽  
pp. 634-635 ◽  
Author(s):  
Lothar Steger ◽  
Udo Engelhardt
Keyword(s):  
Title Compound ◽  
Mass Spectra ◽  
Thiophosphoric Acid ◽  
H Nmr ◽  
Cis And Trans

The title compound,C6H5O-(S)P[NH-NH-Si(CH3)3]2 (1), m. p. 37-39°C, is prepared by silylation of the parent dihydrazide with (CH3)3SiCl in the presence of an excess of base. 1 is purified by vacuum destillation and characterized by 1 H NMR, IR, Ra, mass spectra and analysis. Phosphorus hydrazine heterocycles, such as cis- and trans-C6H5O-(S)P(NH-NH)2P(X)-OC6H5 (X = S, O) and others can be prepared from 1 and C6H5O-(X)PCl2 or other element dihalogene compounds.

Synthesis and reactions of substituted benzofuro[3,2-b]pyrrole derivatives

1982 ◽  
Vol 47 (12) ◽  
pp. 3288-3296 ◽  
Author(s):  
Alžbeta Krutošíková ◽  
Jaroslav Kováč ◽  
Miloslava Dandárová ◽  
Mária Bobálová
Keyword(s):  
Electron Impact ◽  
Mass Spectra ◽  
Pyrrole Derivatives ◽  
H Nmr ◽  
Electron Impact Mass ◽  
Impact Mass ◽  
C Nmr

This paper deals with the preparation of ethyl benzofuro[3,2-b]pyrrole-2-carboxylate, its hydrolysis, N-alkylation, and reduction. Also the synthesis of new heterocyclic systems, benzofuro[3,2-b]pyrrole and 2H-dihydrobenzofuro[2',3':4,5]pyrrolo[1,2-d]-1,2,4-triazin-1-one, is described. The structure of 14 new substances was corroborated by IR, UV, 1H NMR, 13C NMR and electron impact mass spectra.

scholarly journals Binuclear alkynylplatinum(ii) terpyridine complexes with flexible bridges behave as organogelators for several organic solvents

RSC Advances ◽  
2017 ◽  
Vol 7 (24) ◽  
pp. 14389-14394 ◽  
Author(s):  
Ling-Bao Xing ◽  
Fei Qiao ◽  
Zhao Yuan ◽  
Jing-Li Zhang ◽  
Rui-Ying Zhang ◽  
...  
Keyword(s):  
Organic Solvents ◽  
Elemental Analysis ◽  
Mass Spectra ◽  
H Nmr

New binuclear alkynylplatinum(ii) terpyridyl complexes with flexible bridges have been synthesized and characterized by 1H NMR, mass spectra and elemental analysis.

Metallkomplexe mit Tetrapyrrol-Liganden, LVI [1] / Metal Complexes with Tetrapyrrole Ligands, LVI [1]

1990 ◽  
Vol 45 (4) ◽  
pp. 531-542 ◽  
Author(s):  
Johann W. Buchler ◽  
Jürgen Löffler
Keyword(s):  
Cyclic Voltammetry ◽  
Metal Complexes ◽  
Mass Spectra ◽  
Electronic System ◽  
Porphyrin Ring ◽  
H Nmr ◽  
Double Decker ◽  
Porphyrin Rings

The reaction of tris(2,4-pentanedionato)europium(III) with a porphyrin H2(P)** in boiling 1,2,4-trichlorobenzene affords a so-called “redox mixture” of europium(III) bisporphyrinates, i. e. porphyrin π-radicals of the type Eu(P)2 and sandwiches EuH(P)2 in which one of the porphyrin rings is protonated. Thus, from either tetraphenylporphyrin or its dilithium derivative, or octaethylporphyrin, or a mixture of both porphyrins, the corresponding mixtures of double-deckers with two identical or two differnt porphyrin rings are obtained. The transformation of the redox mixtures into the pure tetraphenylporphyrin derivatives Eu(TPP)2, EuH(TPP)2, and the salt [NBu4] [Eu(TPP),, the separation of the octaethylporphyrin derivatives Eu(OEP)2 and EuH(OEP)2, and the purification of the “mixed” double-decker Eu(OEP)-(TPP) are described. The compounds are characterized by cyclic voltammetry, IR, UV/VIS/NIR, 1H NMR, and mass spectra. The obtained data indicate that the π-electrons of the two porphyrin rings behave as a common electronic system in which a defect electron is delocalized. However, in the “mixed” double-decker Eu(OEP) (TPP) the defect electron is more concentrated on the OEP ring, i. e. the porphyrin ring which is more easily oxidized.

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