Kinetics of Reactions of 9-Isothiocyanatoacridine with Aromatic and Aliphatic Amines and Fluorescence Properties of the 1-Acridin-9-yl-3-alkyl(aryl)thioureas Obtained

1994 ◽  
Vol 59 (12) ◽  
pp. 2632-2640 ◽  
Author(s):  
Dana Mazagová ◽  
Pavol Kristian ◽  
Gejza Suchár ◽  
Ján Imrich ◽  
Marián Antalík
Keyword(s):  
Nucleophilic Addition ◽  
Addition Reaction ◽  
Spectroscopic Method ◽  
Reaction Rates ◽  
Aliphatic Amines ◽  
Phenyl Isothiocyanate ◽  
Alkyl Aryl ◽  
Nucleophilic Addition Reaction ◽  
Kinetics Of ◽  
Aromatic And Aliphatic Amines

Kinetics of nucleophilic addition reaction of 9-isothiocyanatoacridine with seventeen aliphatic and aromatic amines in organic solvents has been studied by the VIS spectroscopic method. 9-Isothiocyanatoacridine reacted by about two orders of magnitude faster than phenyl isothiocyanate. The reaction rates of aliphatic amines were markedly affected by steric effects. Excepting 1-acridin-9-yl-3-butylthiourea (IIIo), the products obtained exhibited weaker fluorescence than the starting 9-isothiocyanatoacridine.

scholarly journals Synthesis of multi-substituted indene derivatives from aryl, vinyl, and alkyl/aryl carbinols

2019 ◽  
Author(s):  
Mithun Chakraborty ◽  
Gaddam Mahesh ◽  
Omkar R Nakel ◽  
Gautamee Chavda ◽  
Susarla Anusha ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Nucleophilic Addition ◽  
Addition Reaction ◽  
Nucleophilic Reagent ◽  
Acid Catalyst ◽  
Vinyl Ketone ◽  
Alkyl Aryl ◽  
Excellent Yield ◽  
Nucleophilic Addition Reaction ◽  
Lewis Acid Catalyst

A divergent approach to highly substituted functionalized indenes has been developed. The two-step reaction involving nucleophilic addition reaction of aryl vinyl ketone, an ideal intermediate with aryl or alkyl nucleophilic reagent, followed by electrocyclization (Nazarov cyclization) in the presence of Lewis acid catalyst afforded indene derivatives in good to excellent yield.

Fluorescence Reagents for Labelling of Biomolecules. Part III. Study of the Reactions of 2- and 4-Substituted 9-Isothiocyanatoacridines with Glycine

1994 ◽  
Vol 59 (7) ◽  
pp. 1682-1690 ◽  
Author(s):  
Danica Sabolová ◽  
Dana Mazagová ◽  
Pavol Kristian ◽  
Marián Antalík ◽  
Dušan Podhradský ◽  
...  
Keyword(s):  
Reaction Mechanism ◽  
Fluorescence Intensity ◽  
Nucleophilic Addition ◽  
Fluorescence Spectra ◽  
Addition Reaction ◽  
Kinetic Characteristics ◽  
Reaction Products ◽  
H Nmr ◽  
Nucleophilic Addition Reaction ◽  
Kinetics Of

Kinetics of nucleophilic addition reaction of 2- and 4-substituted 9-isothiocyanatoacridines I - VII with glycine in buffered aqueous dimethylformamide has been studied. The addition products, N-(9-acridinylthiocarbamoyl)glycines VIII - XIV, were characterized by IR, UV, 1H NMR, mass and fluorescence spectra. Derivatives VIII, X and XII exhibited higher fluorescence intensity than the starting isothiocyanates; the highest fluorescence was found for the unsubstituted compound X. The reaction mechanism is discussed on the basis of properties of the reaction products and kinetic characteristics.

Layer by layer assembled functionalized graphene oxide-based polymer brushes for superlubricity on steel-steel tribocontact

Soft Matter ◽  
2021 ◽  
Author(s):  
Suprakash Samanta ◽  
Rashmi Ranjan Sahoo
Keyword(s):  
Graphene Oxide ◽  
Nucleophilic Addition ◽  
Polymer Brushes ◽  
Addition Reaction ◽  
Layer By Layer ◽  
Functionalized Graphene ◽  
Covalent Functionalization ◽  
Functionalized Graphene Oxide ◽  
Nucleophilic Addition Reaction ◽  
Branched Polyethylenimine

Present study demonstrates a simple and multistep approach for the preparation of covalent functionalization of chemically prepared graphene oxide (GO) by branched polyethylenimine (PEI) through nucleophilic addition reaction to prepare...

scholarly journals Catalytic Enantioselective Synthesis of 4-Amino-1,2,3,4-tetrahydropyridine Derivatives from Intramolecular Nucleophilic Addition Reaction of Tertiary Enamides

Synlett ◽  
2018 ◽  
Vol 30 (04) ◽  
pp. 483-487 ◽  
Author(s):  
Shuo Tong ◽  
Mei-Xiang Wang
Keyword(s):  
Phosphoric Acid ◽  
Asymmetric Catalysis ◽  
Nucleophilic Addition ◽  
Addition Reaction ◽  
Enantioselective Synthesis ◽  
Chiral Phosphoric Acid ◽  
Substrate Engineering ◽  
Nucleophilic Addition Reaction ◽  
Engineering Strategy ◽  
Acid Catalyzed

A general and efficient method for the synthesis of highly enantiopure 4-amino-1,2,3,4-tetradydropyridine derivatives based on chiral phosphoric acid catalyzed intramolecular nucleophilic addition of tertiary enamides to imines has been developed. We have also demonstrated a substrate engineering strategy to significantly improve the enantioselectivity of asymmetric catalysis

Nucleophilic addition reaction of aromatic compounds with α-chloroglycidates in the presence of Lewis acid

Tetrahedron ◽  
2003 ◽  
Vol 59 (10) ◽  
pp. 1781-1790 ◽  
Author(s):  
Jing-Rong Lin ◽  
Aidar T Gubaidullin ◽  
Vakhid A Mamedov ◽  
Sadao Tsuboi
Keyword(s):  
Lewis Acid ◽  
Aromatic Compounds ◽  
Nucleophilic Addition ◽  
Addition Reaction ◽  
Nucleophilic Addition Reaction
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