New Metabolites of Streptomyces globisporus and Streptomyces griseus

1993 ◽  
Vol 58 (6) ◽  
pp. 1452-1456 ◽  
Author(s):  
Josef Jizba ◽  
Petr Sedmera ◽  
Marian Beran
Keyword(s):  
Streptomyces Griseus ◽  
Submerged Cultures ◽  
Spectroscopic Measurements ◽  
New Metabolites

5,6,7,7a-Tetrahydro-3H-pyrrolizin-7a-ol-3-one (VI) and N-[2-(1-hydroxy-4-methylpentyl)]acetamide (VII) were isolated from submerged cultures of the macrotetrolide-producing strains Streptomyces globisporus and S. griseus. Proposed structures are based on spectroscopic measurements.

Lactarane Type Sesquiterpenoids as Inhibitors of Leukotriene Biosynthesis and Other, New Metabolites from Submerged Cultures of Lentinellus cochleatus (Pers. ex Fr.) Karst

1996 ◽  
Vol 51 (7-8) ◽  
pp. 493-499 ◽  
Author(s):  
Annette Wunder ◽  
Timm Anke ◽  
Dörte Klostermeyer ◽  
Wolfgang Steglich
Keyword(s):  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Peripheral Blood Leukocytes ◽  
Submerged Cultures ◽  
Blood Leukocytes ◽  
Spectroscopic Investigations ◽  
Basophilic Leukemia ◽  
New Metabolites

Abstract Three known sesquiterpenoids of the lactarane and secolactarane type, deoxylactarorufin A (1), blennin A (2) and blennin C (3), have been obtained from cultures of Lentinellus cochleatus (Basidiomycetes) together with the new metabolites (Z)-2-chloro-3-(4-me-thoxyphenyl)-2-propen-l-ol (4) and lentinellone (5), a protoilludane derivative. The structures were determined by spectroscopic investigations. 1, 2 and 3 are potent inhibitors of leukotriene biosynthesis in rat basophilic leukemia (RBL-1) cells and human peripheral blood leukocytes (PBL).

Secondary metabolites with nematicidal and antimicrobial activity from nematophagous fungi and Ascomycetes

1995 ◽  
Vol 73 (S1) ◽  
pp. 932-939 ◽  
Author(s):  
H. Anke ◽  
M. Stadler ◽  
A. Mayer ◽  
O. Sterner
Keyword(s):  
Linoleic Acid ◽  
Secondary Metabolites ◽  
Biosynthetic Pathway ◽  
Nematophagous Fungi ◽  
Submerged Cultures ◽  
Daldinia Concentrica ◽  
Antimicrobial Metabolites ◽  
Natural Nematicides ◽  
Arthrobotrys Conoides ◽  
New Metabolites

Screening of nematode-trapping fungi for antimicrobial and nematicidal activities gave three new antimicrobial metabolites from cultures of five Arthrobotrys strains. The compounds exhibited no nematicidal activities towards Caenorhabditis elegans and Meloidogyne incognita. From trap-forming submerged cultures of Arthrobotrys conoides, linoleic acid was isolated as a nematicidal principle. Its production increased with the number of traps formed in both Arthrobotrys oligospora and Arthrobotrys conoides. Nematoctonus robustus and Nematoctonus concurrens produced pleurotin, dihydropleurotinic acid, and leucopleurotin, metabolites previously isolated from cultures of Hohenbuehelia species, suggesting that the same biosynthetic pathways function in both the teleomorph and anamorph. Several strains of Ascomycetes had nematicidal activities; linoleic acid was responsible for the activity in cultures of a Chlorosplenium species, 14-epicochlioquinone B in cultures of Neobulgaria pura, and two naphthalenes derived from the melanin biosynthetic pathway in Daldinia concentrica. 5-Pentyl-2-furaldehyde, previously known as a metabolite from a Basidiomycete, was produced by an unidentified Australian Ascomycete. More than 30 mostly new metabolites have been isolated from cultures of Lachnum papyraceum, many being chlorinated. Under different conditions the fungus incorporated bromine instead of chlorine. Key words: nematophagous fungi, natural nematicides, linoleic acid, chlorinated secondary metabolites.

Nomenclature Abstract for Streptomyces griseus alpha (Ciferri 1927) Pridham 1970 (Approved Lists 1980).

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Nicole Danielle Osier ◽  
George M Garrity ◽  
Dorothea Taylor
Keyword(s):  
Streptomyces Griseus

Kinetics of catalytic reduction of nitrogen oxide by carbon monoxide on CuO/Al2O3 catalyst

1983 ◽  
Vol 48 (11) ◽  
pp. 3202-3208 ◽  
Author(s):  
Zdeněk Musil ◽  
Vladimír Pour
Keyword(s):  
Carbon Monoxide ◽  
Nitrogen Oxide ◽  
Rate Equation ◽  
Catalytic Reduction ◽  
Zero Order ◽  
Spectroscopic Measurements ◽  
First Order ◽  
Ir Spectroscopic ◽  
Kinetics Of ◽  
Al2o3 Catalyst

The kinetics of the reduction of nitrogen oxide by carbon monoxide on CuO/Al2O3 catalyst (8.36 mass % CuO) were determined at temperatures between 413 and 473 K. The reaction was found to be first order in NO and zero order in CO. The observed kinetics are consistent with a rate equation derived from a mechanism proposed on the basis of IR spectroscopic measurements.

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