Reactions of Triformylmethane with Adamantane Derivatives Containing Primary Amino Group

1992 ◽  
Vol 57 (9) ◽  
pp. 1947-1950 ◽  
Author(s):  
Jiří Burkhard ◽  
Zdeněk Arnold

Six new compounds were obtained by condensation of triformylmethane with some aminoadamantane derivatives. The study also includes 7-amino-1,3,5-triazaadamantane.

Polyhedron ◽  
2009 ◽  
Vol 28 (18) ◽  
pp. 3985-3992 ◽  
Author(s):  
Marie Sotolářová ◽  
Jan Houška ◽  
Marek Nečas ◽  
Josef Havel ◽  
Jiří Příhoda

Molecules ◽  
2022 ◽  
Vol 27 (2) ◽  
pp. 545
Author(s):  
Niccolò Chiaramonte ◽  
Alessio Gabellini ◽  
Andrea Angeli ◽  
Gianluca Bartolucci ◽  
Laura Braconi ◽  
...  

A series of histamine (HST)-related compounds were synthesized and tested for their activating properties on five physiologically relevant human Carbonic Anhydrase (hCA) isoforms (I, II, Va, VII and XIII). The imidazole ring of HST was replaced with different 5-membered heterocycles and the length of the aliphatic chain was varied. For the most interesting compounds some modifications on the terminal amino group were also performed. The most sensitive isoform to activation was hCA I (KA values in the low micromolar range), but surprisingly none of the new compounds displayed activity on hCA II. Some derivatives (1, 3a and 22) displayed an interesting selectivity for activating hCA I over hCA II, Va, VII and XIII.


1994 ◽  
Vol 35 (27) ◽  
pp. 4773-4776 ◽  
Author(s):  
Béatrice Dumont ◽  
Marie-Françoise Schmitt ◽  
Jean-Pierre Joly

1972 ◽  
Vol 21 (3) ◽  
pp. 363-366 ◽  
Author(s):  
Daido ISHII ◽  
Takao TSUDA ◽  
Nobuo TOKORO

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