(+)-3α-Hydroxylupanine, a new alkaloid from Ammopiptanthus mongolicus (MAXIM.) CHENG F.

1990 ◽  
Vol 55 (5) ◽  
pp. 1257-1265 ◽  
Author(s):  
Bohumil Proksa ◽  
Dušan Uhrín ◽  
Stanislava Uhrínová ◽  
Eduard Grossmann ◽  
Dangaa Selenge ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Spectral Data ◽  
Ammopiptanthus Mongolicus ◽  
First Time

From leaves of Ammopiptanthus mongolicus (MAXIM.) CHENG F. were isolated (+)-3α-hydroxylupanine (I), (1R)-3-O-methyl[1,2,4/3,5,6]-inositol (V), salicylic acid, (-)-piptanthine (III), 7-hydroxy-4'-methoxyisoflavone (VIII), 7,3'-dihydroxy-4'-methoxyisoflavone (X) and 4'-methoxyisoflavone-7-β-D-glucopyranoside (IX). All the compounds were characterized on the basis of spectral data; the first three compounds were isolated from this material for the first time.

scholarly journals Chemical Constituents of the Marine Sponge Aaptos aaptos (Schmidt, 1864) and Their Cytotoxic Activity

2021 ◽  
Vol 16 (2) ◽  
pp. 1934578X2199334
Author(s):  
Do Thi Trang ◽  
Bui Huu Tai ◽  
Dan Thuy Hang ◽  
Pham Hai Yen ◽  
Phan Thi Thanh Huong ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Spectral Data ◽  
Absolute Configuration ◽  
Marine Sponge ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Extensive Analysis ◽  
First Time ◽  
Tddft Method ◽  
Mcf 7

Seven compounds (1-7) were isolated from the marine sponge Aaptos aaptos living in the Vietnamese sea. Their structures were determined as 2 hours, 5 H,7 H,9 H-9 S-hydroxy-imidazo[1,5- α]pyridine-1,3-dione (1), 3-([9-methylhexadecyl]oxy)propane-1,2-diol 2, 2,3-dihydro-2,3-dioxoaaptamine (3), indol-3-aldehyde (4), methyl indole-3-carboxylate (5) 4-hydroxy-5-(indole-3-yl)−5-oxo-pentan-2-one (6), and thymidine (7) by extensive analysis of HR-ESI-MS, 1D, and 2D NMR spectral data, as well as by comparison of the spectral data with those reported in the literature. In addition, the absolute configuration of 1 was determined from the experimental ECD spectrum and comparison of this with the theoretical ECD calculations using the TDDFT method. Compounds 1 and 2 were isolated from nature for the first time. Compound 3 induced cytotoxic activity against SK-LU-1, MCF-7, HepG2, and SK-Mel-2 cell lines with IC50 values of 41.27 ± 2.63, 40.70 ± 2.65, 34.31 ± 3.43, and 36.63 ± 1.40 µM, respectively.

Chemical components of the rhizomes of Drynaria fortunei (KUNZE) J. Sm. (polypodiaceae) in Vietnam

2011 ◽  
Vol 76 (9) ◽  
pp. 1133-1139 ◽  
Author(s):  
Pham Thi Nhat Trinh ◽  
Nguyen Cong Hao ◽  
Phan Thanh Thao ◽  
Le Tien Dung
Keyword(s):  
Data Analysis ◽  
Spectral Data ◽  
Phenolic Acid ◽  
Ethanol Extract ◽  
Chemical Components ◽  
Spectroscopic Methods ◽  
Phenylpropanoid Glycoside ◽  
Spectral Data Analysis ◽  
First Time

From the ethanol extract of Drynaria fortunei (KUNZE) J. Sm., a new phenylpropanoid glycoside, fortunamide (1), was isolated and characterized by spectroscopic methods. Together with a new glycoside, 9 known compounds, including three curcuminoids (2–4), two isoprenylated flavonoids (5, 6), two flavonoids (7, 8), one monoterpenoid (9) and one phenolic acid (10) were isolated and identified by spectral data analysis from the rhizomes of Drynaria fortunei (KUNZE) J. Sm. Eight of them were isolated from Drynaria fortunei (KUNZE) J. Sm. for the first time.

scholarly journals Doppler Tomography in 2D and 3D of the X-ray Binary Cyg X-1 for June 2007

2011 ◽  
Vol 7 (S282) ◽  
pp. 201-202 ◽  
Author(s):  
O. I. Sharova ◽  
M. I. Agafonov ◽  
E. A. Karitskaya ◽  
N. G. Bochkarev ◽  
S. V. Zharikov ◽  
...  
Keyword(s):  
Binary System ◽  
Spectral Data ◽  
Inclination Angle ◽  
Tomographic Reconstruction ◽  
Orbital Plane ◽  
National Observatory ◽  
Doppler Tomography ◽  
X Ray ◽  
2D And 3D ◽  
First Time

AbstractThe 2D and 3D Doppler tomograms of X-ray binary system Cyg X-1 (V1357 Cyg) were reconstructed from spectral data for the line HeII 4686Å obtained with 2-m telescope of the Peak Terskol Observatory (Russia) and 2.1-m telescope of the Mexican National Observatory in June, 2007. Information about gas motions outside the orbital plane, using all of the three velocity components Vx, Vy, Vz, was obtained for the first time. The tomographic reconstruction was carried out for the system inclination angle of 45°. The equal resolution (50 × 50 × 50 km/s) is realized in this case, in the orbital plane (Vx, Vy) and also in the perpendicular direction Vz. The checkout tomograms were realized also for the inclination angle of 40° because of the angle uncertainty. Two versions of the result showed no qualitative discrepancy. Details of the structures revealed by the 3D Doppler tomogram were analyzed.

A new natural indole and three aporphine alkaloids from Monodora bevipes Benth. (Annonaceae)

2017 ◽  
Vol 6 (7) ◽  
pp. 40-43
Author(s):  
Dade J.M. Eric ◽  
Coulibali Siomenan ◽  
Kouamé Bi Koffi François Prévost ◽  
Kablan Ahmont Landry Claude ◽  
Kodjo Charles ◽  
...  
Keyword(s):  
Spectral Data ◽  
Pharmaceutical Journal ◽  
First Time

Four compounds were isolated from the leaves of Monodora brevipes Benth. (Annonaceae). Among them, one new natural indole named 5-formylindole (1) and three known aporphine alkaloids: (+)-roemeroline (2); (+)-corydine (3) and (+)-menispermine (4). They were isolated for the first time from this species. The structures of these compounds were established according to their spectral data (NMR, SM, IR and UV).Eric et al., International Current Pharmaceutical Journal, June 2017, 6(7): 40-43http://www.icpjonline.com/documents/Vol6Issue7/01.pdf

scholarly journals Natural Clovanes from the Gorgonian Coral Rumphella Antipathies

2013 ◽  
Vol 8 (8) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Hsu-Ming Chung ◽  
Wei-Hsien Wang ◽  
Tsong-Long Hwang ◽  
Yang-Chang Wu ◽  
Ping-Jyun Sung
Keyword(s):  
Spectral Data ◽  
Natural Source ◽  
Human Neutrophils ◽  
Spectroscopic Methods ◽  
Superoxide Anions ◽  
Inhibitory Effects ◽  
Gorgonian Coral ◽  
First Time

Three natural clovane-related sesquiterpenoids, 2β-acetoxyclovan-9α-ol (1), 9α-acetoxyclovan-2β-ol (2) and clovan-2β,9β-diol (3), were isolated from the gorgonian coral Rumphella antipathies. The structures of clovanes 1–3 were elucidated by spectroscopic methods and by comparison of the spectral data with those of known clovane analogues. This is the first time that clovanes 1–3 have been isolated from a natural source. Clovanes 1 and 2 displayed inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils.

scholarly journals The Constituents of the Stems of Cissus assamica and Their Bioactivities

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2799 ◽  
Author(s):  
Yu-Yi Chan ◽  
Chiu-Yuan Wang ◽  
Tsong-Long Hwang ◽  
Shin-Hun Juang ◽  
Hsin-Yi Hung ◽  
...  
Keyword(s):  
Spectral Data ◽  
Betulinic Acid ◽  
Small Cell Lung Carcinoma ◽  
Cell Lung Carcinoma ◽  
Pheophytin A ◽  
Mass Spectral ◽  
Ic50 Value ◽  
Ic50 Values ◽  
Hct 116 ◽  
First Time

Fifty-five compounds were isolated from the fresh stems of Cissus assamica, including 14 benzenoids, 11 triterpenes, nine steroids, five tocopherols, five chlorophylls, four flavonoids, two benzoquinones, two tannins, and three other compounds. Their structures were constructed by 1D and 2D nuclear magnetic resonance (NMR) and mass spectral data, and were also identified by a comparison of their spectral data with those reported in the literature. Among these isolates, 1,2-bis-(5--tocopheryl) ethane (51) was reported for the first time from natural sources. Some purified compounds were examined for their anti-inflammatory and anticancer bioactivities. The results indicated that betulinic acid (16) exhibited strong inhibition of superoxide anion generation with IC50 value of 0.2 ± 0.1 μM, while betulinic acid (16) and pheophytin-a (47) inhibited elastase release with IC50 value of 2.7 ± 0.3 and 5.3 ± 1.0 μM, respectively. In addition, betulinic acid (16) and epi-glut-5(6)-en-ol (18) exhibited potential cytotoxicity to non-small-cell lung carcinoma (NCI-H226) and colon cancer (HCT-116) cell lines with IC50 values in the range of 1.6 to 9.1 μM.

scholarly journals The Appearance and Disappearance of Exocomet Gas Absorption

2015 ◽  
Vol 2015 ◽  
pp. 1-20 ◽  
Author(s):  
Barry Y. Welsh ◽  
Sharon L. Montgomery
Keyword(s):  
Spectral Data ◽  
Spectral Type ◽  
Gas Absorption ◽  
Stellar Systems ◽  
Activity Levels ◽  
Line Profiles ◽  
Short Term ◽  
Line Absorption ◽  
First Time ◽  
Parent Star

CaII K-line (3933 Å) absorption profiles observed towards 15 A-type and two B-type stars with known (or suspected) debris disks, in addition to archival spectral data for three A-type stars, are presented. Inspection of the extracted CaII K-line absorption lines has determined that one late B-type (HD 58647) and four new A-type (HD 56537, HD 64145, HD 108767, and HD 109573) stellar systems exhibit short-term (night-to-night) absorption variation within these profiles. This variability is due to the liberation of gas from falling evaporating bodies (the so-called FEBs activity) on the grazing approach of exocomets towards their parent star. Also we present archival spectra of the FeIλ3860 Å and CaII K-lines towardsβPictoris (HD 39060) that, for the first time, reveal the absorption signatures of FEB activity at similar velocities inbothline profiles. FEB-hosting stars seem to be of an earlier type (on average spectral type Al.8 as compared with A3.1) than those where no FEB activity has been observed. This could be due to stellar activity levels (such as chromospheric activity or nonradial pulsations) being of a higher level within the atmospheres of these hotter A-type stars.

scholarly journals A Phenylpropanoid and Biflavonoids from the Needles of Cephalotaxus harringtonia var. harringtonia

2017 ◽  
Vol 12 (11) ◽  
pp. 1934578X1701201 ◽  
Author(s):  
Anju Mendiratta (Nee Chugh) ◽  
Rameshwar Dayal ◽  
John P. Bartley ◽  
Graham Smith
Keyword(s):  
Nmr Spectroscopy ◽  
Oral Dose ◽  
Spectral Data ◽  
2D Nmr ◽  
Hepatoprotective Activity ◽  
X Ray Diffraction ◽  
Soluble Extract ◽  
2D Nmr Spectroscopy ◽  
X Ray ◽  
First Time

A phenylpropanoid [2-(3-methoxy-4-hydroxyphenyl)-propane-1,3-diol] (1) together with four known biflavonoids namely 7, 4′, 7′″, 4′″-tetra- O-methyl amentoflavone (2); 7, 4′, 7″-tri- O-methyl amentoflavone (3); ginkgetin (4); sequoiaflavone (5) were isolated from the acetone soluble extract of needles of Cephalotaxus harringtonia var. harringtonia. Their structures were elucidated mainly on the basis of interpretation of 1D and 2D NMR spectroscopy and X-ray diffraction studies. The detailed spectral data of phenylpropanoid have been described for the first time. Ginkgetin (4) exhibited significant hepatoprotective activity in rat at 6 mg/kg oral dose level.

scholarly journals DAMMARANE-TYPE TRITERPENOIDS FROM THE STEMBARK OF CHISOCHETON PENTANDRUS (MELIACEAE)

Jurnal Kimia ◽  
2020 ◽  
pp. 89
Author(s):  
D. G. Katja ◽  
S. Salam ◽  
. Nurlelasari ◽  
D. Harneti ◽  
R. Maharani ◽  
...  
Keyword(s):  
Spectral Data ◽  
Spectroscopic Data ◽  
Hexane Extract ◽  
First Time

Two dammarane-type triterpenoids, cabraleadiol (1) and cabraleahydroxylactone (2), have been isolated from n-hexane extract of the stembark of  Chisocheton pentandrus (Meliaceae). The structure of compounds 1 and 2 were determined by spectroscopic data mainly NMR and mass as well as by comparing with previously reported spectral data. Compounds 1 and 2 were reported for the first time from Chisocheton pentandrus.   Keywords:   Cabraleadiol, Cabraleahydroxylactone, Chisocheton pentandrus, Meliaceae.

scholarly journals Structures of New Phenolic Glycosides from the Seeds of Cucurbita Moschata

2009 ◽  
Vol 4 (4) ◽  
pp. 1934578X0900400
Author(s):  
Li Fa-Sheng ◽  
Xu Jing ◽  
Dou De-Qiang ◽  
Chi Xiao-Feng ◽  
Kang Ting-Guo ◽  
...  
Keyword(s):  
Spectral Data ◽  
Spectroscopic Analysis ◽  
Phenolic Glycosides ◽  
Phenolic Glycoside ◽  
Cucurbita Moschata ◽  
Reported Data ◽  
First Time ◽  
Chemical Evidence

A new phenolic glycoside and three known compounds were isolated from the seeds of Cucurbita moschata. The structures of the new compound was elucidated as phenylcarbinyl 5-O-(4-hydroxy)benzoyl-β-D-apiofuranosyl (1→2)-β-D-glucopyranoside on the basis of spectroscopic analysis and chemical evidence. Three known compounds were identified as 1-O-benzyl[5-O-benzoyl-β-D-apiofuranosyl(1→2)]-β-D-glucopyranoside 2, cucurbitosides C 3 and A 4, by comparison of the spectral data with reported data. Compound 2 was isolated from this plant for the first time.

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