Interaction of human hemoglobin with oxygen in the presence of benzene and use of computer for construction of saturation curves

1986 ◽  
Vol 51 (8) ◽  
pp. 1795-1801
Author(s):  
Hana Hájková ◽  
Zdeněk Pavlíček ◽  
Vítěz Kalous
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Pressure ◽  
Time Profile ◽  
Partial Oxygen Pressure ◽  
Human Hemoglobin ◽  
Allosteric Interaction ◽  
Partial Oxygen

The time profile of changes in the oxygen saturation curves of human hemoglobin in the presence of benzene was investigated. The partial oxygen pressure p50, necessary for a half saturation, decreases during the first 3.5 h of interaction of hemoglobin with benzene and did not change afterwards. The character of changes in Hill's coefficient was similar. The oxygen saturation was modeled both for hemoglobin alone and, using MWC as a model of allosteric interaction, also for hemoglobin and benzene in a computer.

scholarly journals Mismatch between Tissue Partial Oxygen Pressure and Near-Infrared Spectroscopy Neuromonitoring of Tissue Respiration in Acute Brain Trauma: The Rationale for Implementing a Multimodal Monitoring Strategy

2021 ◽  
Vol 22 (3) ◽  
pp. 1122
Author(s):  
Mario Forcione ◽  
Mario Ganau ◽  
Lara Prisco ◽  
Antonio Maria Chiarelli ◽  
Andrea Bellelli ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Oxygen Pressure ◽  
Near Infrared ◽  
Optical Signal ◽  
Brain Trauma ◽  
Partial Oxygen Pressure ◽  
Tissue Respiration ◽  
The Brain ◽  
Partial Oxygen

The brain tissue partial oxygen pressure (PbtO2) and near-infrared spectroscopy (NIRS) neuromonitoring are frequently compared in the management of acute moderate and severe traumatic brain injury patients; however, the relationship between their respective output parameters flows from the complex pathogenesis of tissue respiration after brain trauma. NIRS neuromonitoring overcomes certain limitations related to the heterogeneity of the pathology across the brain that cannot be adequately addressed by local-sample invasive neuromonitoring (e.g., PbtO2 neuromonitoring, microdialysis), and it allows clinicians to assess parameters that cannot otherwise be scanned. The anatomical co-registration of an NIRS signal with axial imaging (e.g., computerized tomography scan) enhances the optical signal, which can be changed by the anatomy of the lesions and the significance of the radiological assessment. These arguments led us to conclude that rather than aiming to substitute PbtO2 with tissue saturation, multiple types of NIRS should be included via multimodal systemic- and neuro-monitoring, whose values then are incorporated into biosignatures linked to patient status and prognosis. Discussion on the abnormalities in tissue respiration due to brain trauma and how they affect the PbtO2 and NIRS neuromonitoring is given.

Synthesis of monophase HgBa2CuO4+δ under controlled partial oxygen pressure

1995 ◽  
Vol 255 (3-4) ◽  
pp. 173-179 ◽  
Author(s):  
V.A. Alyoshin ◽  
D.A. Mikhailova ◽  
E.V. Antipov
Keyword(s):  
Oxygen Pressure ◽  
Partial Oxygen Pressure ◽  
Partial Oxygen

scholarly journals Correlation Between The Inspired Fraction Of Oxygen, Maternal Partial Oxygen Pressure, And Fetal Partial Oxygen Pressure During Cesarean Section Of Normal Pregnancies

2009 ◽  
Vol 59 (4) ◽  
pp. 452-460 ◽  
Author(s):  
Carlos Henrique Viana de Castro ◽  
Marcos Guilherme Cunha Cruvinel ◽  
Fabiano Soares Carneiro ◽  
Yerkes Pereira Silva ◽  
Antônio Carlos Vieira Cabral ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Oxygen Pressure ◽  
Partial Oxygen Pressure ◽  
Partial Oxygen

Effect of a medicinal agent, possessing antioxidant and antihypoxant properties, on the state of oxygen homeostasis and lipid peroxidation under experimental pneumoconiosis in albino rats

2018 ◽  
Vol 8 (2) ◽  
pp. 137-143
Author(s):  
A. Olyinyk ◽  
A Ślifirczyk ◽  
M. Nikoniuk ◽  
M. Celiński ◽  
D> Domańska
Keyword(s):  
Lipid Peroxidation ◽  
Oxygen Pressure ◽  
Oxygen Metabolism ◽  
Conjugated Dienes ◽  
Partial Oxygen Pressure ◽  
Albino Rats ◽  
Blood Oxygen Saturation ◽  
Arterial Blood ◽  
Conjugated Dienes And Trienes ◽  
Partial Oxygen

Introduction: Pneumoconioses (Pc) are interstitial pulmonary diseases of professional genesis, caused by long-term inhalation of high dust concentrations. Pcafflict 26.6-53% of the workers, exposed to dust contamination. The major feature of Pc course is irrevocability and incurability. Purpose: The research of the effect of ethylmethyl hydroxypyridine succinate, possessing antioxidant and antihypoxant characteristics, on the oxygen metabolism, acid-alkaline state, and lipid peroxidation at the background of experimental pneumoconiosis in albino rats. Material and methods: Pneumoconiosis was simulated on 72 albino rats through endotracheal injection of black coal suspension, on our own modification of O. Yu. Nykolenko methodology. Results: Manifestations of experimental pneumo-coniosis depended on the period of dust inhalation. Development of experimental pneumoconiosis was found to result in the decreased partial oxygen pressure in the arterial blood, compensated hyperventilation-induced respiratory alkalosis, and marked increase in lipid peroxidation activity that could be seen in the blood content of malon-dialdehyde, as well as of conjugated dienes and trienes. Conclusions: Application of ethylmethylhydroxy pyridine succinate in experimental pneumoconiosis has been found to improve oxygen metabolism, acid-alkaline state, and lipid peroxidation that is revealed in normalization of the partial oxygen pressure in the arterial blood, oxygen saturation of haemoglobin, index of bases’ deficiency BE (Ваse-Ехсеss), and in 1.6-2.0 decrease in the content of malondialdehyde, as well as of conjugated dienes and trienes.

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