Kinetics and thermodynamics of the reaction between thyroxine and antithyroxine antiserum under the conditions of radioimmunoanalysis

1982 ◽  
Vol 47 (8) ◽  
pp. 2077-2086
Author(s):  
Peter Talán ◽  
Juraj Mucha
Keyword(s):  
Reaction Rate ◽  
Serum Proteins ◽  
Relative Rate ◽  
Order Reaction ◽  
Second Order ◽  
Second Order Reaction ◽  
Reaction Enthalpy ◽  
Thermodynamics And Kinetics ◽  
Relative Rate Constants ◽  
Kinetics Of

Thermodynamics and kinetics of the reaction between thyroxine and antithyroxine antiserum has been studied using the concentration and temperature conditions usual in the radioimmunoanalysis. The reaction is assumed to be homogeneous and of the second order. Because of the initial concentrations of thyroxine and of the free bonds of the heterogeneous population of antibodies present in the used antiserum the rate constant equation for second-order reaction has been used in the integrated form. The relative rate constants have been obtained and the activation energy of the reaction in absence of the serum proteins in the reaction mixture or, respectively, in the presence of the euthyroidic serum has been calculated. The nature of the effect of so-called deblockators (J) (8-anilino-1-naphthalene sulphonic acid and tiomersal) on the reaction rate and on the change of the reaction enthalpy (or entropy) has also been investigated. The association constant of this reaction has been evaluated from the radioimmunoanalytical data transformed by the Scatchard relation, modified for the conditions of thyroxine radioimmunoanalysis.

Kinetics of the reaction between hexamethylenediisocyanate and 1-pentanol

1983 ◽  
Vol 48 (11) ◽  
pp. 3279-3286
Author(s):  
Slavko Hudeček ◽  
Miloslav Bohdanecký ◽  
Ivana Hudečková ◽  
Pavel Špaček ◽  
Pavel Čefelín
Keyword(s):  
Liquid Chromatography ◽  
Rate Constants ◽  
Reversed Phase ◽  
Order Reaction ◽  
Second Order ◽  
Second Order Reaction ◽  
Reversed Phase Liquid Chromatography ◽  
Consecutive Reactions ◽  
Phase Liquid ◽  
Kinetics Of

The reaction between hexamethylenediisocyanate and 1-pentanol in toluene was studied by means of reversed-phase liquid chromatography. By employing this method, it was possible to determine all components of the reaction mixture including both products, i.e. N-(6-isocyanate hexyl)pentylcarbamate and N,N'-bis(pentyloxycarbonyl)hexamethylenediamine. Relations for the calculation of kinetic constants were derived assuming a competitive consecutive second-order reaction. It was demonstrated that the reaction involved in this case is indeed a second-order reaction, and the rate constants of the first and second consecutive reactions were determined.

scholarly journals The alcoholysis of 1,2,2-trimethylpropyl-methylfluorophosphonate

2000 ◽  
Vol 65 (12) ◽  
pp. 857-866
Author(s):  
Mladjen Micevic ◽  
Slobodan Petrovic
Keyword(s):  
Kinetic Data ◽  
Reaction Rate ◽  
Frequency Factor ◽  
Reaction Rate Constant ◽  
Order Reaction ◽  
Activation Entropy ◽  
Second Order Reaction ◽  
Third Order ◽  
First Order ◽  
Kinetics Of

The alcoholysis of 1,2,2-trimethylpropyl-methylfluorophosphonate (soman) was examined with a series of alkoxides and in corresponding alcohols: methanol, ethanol, 1-propanol, 2-propanol, 2-methoxyethanol and 2-ethoxyethanol. Soman reacts with the used alkoxides in a second order reaction, first order in each reactant. The kinetics of the reaction between 1,2,2-trimethylpropyl-methylfluorophosphonate and ethanol in the presence of diethylenetriamine was also examined. A third order reaction rate constant was calculated, first order in each reactant. The activation energy, frequency factor and activation entropy were determined on the basis of the kinetic data.

Influence of DNA on the Reaction Rate of an Electron Transfer Process: A Kinetic Study of the Reaction Between [Co(Pyrazinecarboxylate)(NH3)4]2+ and [Fe(CN)6]4- in Aqueous Solutions in the Presence of DNA

2002 ◽  
Vol 67 (8) ◽  
pp. 1165-1172 ◽  
Author(s):  
Manuel López-López ◽  
Plácido Cárdeno ◽  
Francisco J. del Castillo ◽  
Luis González ◽  
Ana R. Méndez ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Aqueous Solutions ◽  
Reaction Rate ◽  
Transfer Reaction ◽  
Electron Transfer Reaction ◽  
Order Reaction ◽  
Second Order Reaction ◽  
Electron Transfer Process ◽  
Pseudophase Model ◽  
Kinetics Of

The kinetics of the electron transfer reaction between tetraammine(pyrazinecarboxylate)cobalt(III), [Co(pyrazinecarboxylate)(NH3)4]2+, and hexacyanoferrate(II), [Fe(CN)6]4- was studied in aqueous solutions in the presence of DNA at concentrations 0-2.28 · 10-3 mol dm-3. A decrease in the rate constant with increasing DNA concentration was observed. The results are interpreted on the basis of the pseudophase model. The meaning of its parameters for the second-order reaction is discussed.

scholarly journals Sulfate radical-based oxidation of an alcohol ethoxylate (Brij30®) by the PS/UV-C process

2020 ◽  
Vol 81 (2) ◽  
pp. 383-394
Author(s):  
Ç. Ecer Uzun ◽  
I. Kabdaşlı ◽  
T. Olmez-Hanci ◽  
O. Tünay
Keyword(s):  
Reaction Rate ◽  
Kinetic Method ◽  
Order Reaction ◽  
Second Order ◽  
Sulfate Radical ◽  
Alcohol Ethoxylate ◽  
Second Order Reaction ◽  
Ph Values ◽  
Initial Ph ◽  
Uv C

Abstract In this study, sulfate radical-based oxidation of an alcohol ethoxylate (AE) was explored by the persulfate (PS)/UV-C process. Poly(oxyethylene)(4)laurylether, commercially known as Brij30®, was used as a model AE. PS/UV-C oxidation of aqueous Brij30® (8–20 mg/L) was performed at initial PS concentrations varying between 0.50 and 6.50 mM and at initial pH values of 3.0 and 6.0. Results indicated that an increase in both initial PS and Brij30® concentrations did not have a significant effect on Brij30® removal efficiency and that Brij30® abatements of more than 90% could be achieved after 60 min of treatment time. Total organic carbon (TOC) removals were significantly improved with increasing initial PS concentrations for both initial pH values. On the other hand, an increase in initial Brij30® concentration had a negative effect on mineralization. By employing the competitive kinetic method, the second-order reaction rate coefficient of Brij30® with the sulfate radical (SO4•−) was determined as 1.62 × 109 ± 3.5 × 107 M−1s−1. The second-order reaction rate constant of TOC, originating from Brij30® and reaction intermediates, was found to be 9.09 × 105 ± 2.91 × 105 M−1s−1 and 1.13 × 106 ± 0.46 × 106 M−1s−1 for pH values of 6.0 and 3.0, respectively. Toxicity of PS/UV-C treated aqueous Brij30® solutions towards Vibrio fischeri was also investigated to determine the possible toxic behavior of oxidation products.

Kinetics of the reaction of methyl iodide with sulfite and thiosulfate ions in aqueous solution

1969 ◽  
Vol 47 (24) ◽  
pp. 4537-4541 ◽  
Author(s):  
R. A. Hasty ◽  
S. L. Sutter
Keyword(s):  
Activation Energy ◽  
Methyl Iodide ◽  
Reaction Rate ◽  
Reaction Rate Constant ◽  
Order Reaction ◽  
Second Order Reaction ◽  
Kcal Mole ◽  
Rate Of Reaction ◽  
Kinetics Of ◽  
Sulfite Ion

The rate of reaction of methyl iodide with sulfite ion is determined. In addition, the rate of reaction of methyl iodide with thiosulfate ion is reexamined and the rate of reaction of methyl iodide with bisulfite ion is estimated. A pronounced effect of ionic strength on the reaction rate in the methyl iodide – sulfite ion system is observed, this effect does not occur in the methyl iodide – thiosulfate ion system. The second order reaction rate constant and activation energy for the reaction of methyl iodide with the respective nucleophiles are: SO32−, 4.4 × 10−2M−1 s−1, 18.6 kcal mole−1; HSO3−, 1 × 10−3M−1 s−1, 18.4 kcal mole−1; and S2O32− 3.1 × 10−2M−1 s−1, 19.4 kcal mole−1.

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