Alkaloids of Buxus sempervirens var rotundifolia BAILLON

1981 ◽  
Vol 46 (6) ◽  
pp. 1425-1432 ◽  
Author(s):  
Le thi Thien Huong ◽  
Zdeno Votický ◽  
Vladimír Paulík
Keyword(s):  
Spectral Data ◽  
Physical Data ◽  
Physico Chemical ◽  
Buxus Sempervirens ◽  
Chemical Constant

Twenty one alkaloids were isolated from the leaves of Buxus sempervirens var rotundifolia BAILLON. Buxaminol-B, cyclobuxine-D, cyclovirobuxine-D, cycloprotobuxine-C, buxamine-E, buxtauine-M and buxpiine-K were those already known. New alkaloids, the constitution and configuration of which were inferred from physical data and corroborated by interconversion and correlation, were denominated buxithienine-M and cyclobuxophylline-O. The remaining bases were characterized by physico-chemical constant and/or spectral data.

Multivariate analysis of physico-chemical, bioactive, microbial and spectral data characterisation of Algerian honey

2021 ◽  
Author(s):  
Fatima Zohra Issaad ◽  
Khalid Bouhedjar ◽  
Assia Ikhlef ◽  
Hatem Lachlah ◽  
Djihene Hadj Smain ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Spectral Data ◽  
Physico Chemical

scholarly journals Synthesis and Structural Characterization of Lanthanum(III) Complexes of 4-Nitrosoantipyrine

2021 ◽  
Vol 33 (3) ◽  
pp. 617-621
Author(s):  
Meera Gopal ◽  
Sreesha Sasi
Keyword(s):  
Magnetic Susceptibility ◽  
Spectral Data ◽  
General Formula ◽  
Structural Characterization ◽  
Bidentate Ligand ◽  
Bidentate Ligands ◽  
Nitroso Group ◽  
Physico Chemical ◽  
Chemical Studies

A new series of La(III) complexes of the ligand with the general formula [La(L)2(a)3] and [La2(L)4(aa)3], (a = nitrate (1), thiocyanate (2), acetate (3) and propionate (4) ions, aa = sulphate (5), thiosulphate (6), oxalate (7) and malonate (8) ions with the ligand 4-nitrosoantipyrine (L) were synthesized and characterized using various physico-chemical studies. The primary ligand L acts as a bidentate ligand utilizing the carbonyl group and the nitroso group for bonding. The nitrate, thiocyanate, acetate and propionate ions are monovalent unidentate ligands, whereas sulphate, thiosulphate, oxalate and malonate ions are divalent bidentate ligands in the complexes 1-8. Based on spectral data and magnetic susceptibility measurements, geometry of the lanthanum(III) complexes were also proposed.

scholarly journals Preparation and Characterisation of complex Bis(pentafluorophenyl) antimony(V) anions of the type [(Rf)2SbCl3X]-

2013 ◽  
Vol 1 (3) ◽  
pp. 90-96 ◽  
Author(s):  
Ram Nath Prasad Yadav
Keyword(s):  
Solid State ◽  
Spectral Data ◽  
General Formula ◽  
1H Nmr ◽  
Elemental Analysis ◽  
19F Nmr ◽  
Chemical Data ◽  
Molecular Weights ◽  
Counter Ions ◽  
Physico Chemical

A series of hiteherto unreported solid salts of hexa-coordinated anions of the general formula [(Rf)2SbCl3X]- , where Rf = C6F5 ; L = Cl and X = Cl, Br, I, N3, NCS and SeCN have been prepared in the presence of tetraorgano ammonium, phosphonium, arsonium and stibonium counter ions. The complexes have been formulated and characterised on the basis of elemental analysis, molar conductances, molecular weights and solid state IR, solution state 1H NMR and 19F NMR spectral data. The physico-chemical data are consistent with six-coordinate antimony complexes.DOI: http://dx.doi.org/10.3126/ijasbt.v1i3.8304 Int J Appl Sci Biotechnol, Vol. 1(3) 2013 : 90-96

scholarly journals Synthesis, physico-chemical properties and bioloclical activitv of 1-(4-fluorophenvl)-4-[3-(2-,3- and 4-alkyloxyphenylcarbamoyloxy)-2-hydroxypropyl] piperaziniumchlorides

2004 ◽  
Vol 72 (4) ◽  
pp. 283-291 ◽  
Author(s):  
Ivan Malík ◽  
Eva Sedlárová ◽  
Jozef Csöllel ◽  
Eva Račanská ◽  
Jozef Čižmárik ◽  
...  
Keyword(s):  
Spectral Data ◽  
Aromatic Ring ◽  
Guinea Pigs ◽  
Chemical Properties ◽  
Antiarrhythmic Activity ◽  
Alkoxy Group ◽  
Bulky Substituent ◽  
Physico Chemical ◽  
Derivatives Of

1-(4-fluoropheny1)-4-[3-(2-,3- and 4-alkyloxyphenylcarbamoyloxy)-2-hydroxypropyl]piperaziniumchlorides, with one to four carbon atoms in the alkoxy group on aromatic ring have been synthesized as the derivatives of substituted phenylcarbamic acid. The structures were confirmed by their spectral data. Potential antiarrhythmic activity was evaluated in guinea-pigs model. Preliminary studies demonstrated that the evaluated compounds, using ouabain arrhythmia model, appear to possess only moderate antiarrhythmic activity. Only compound marked as 4f appears to be more potent and lead us to focus our attention on structures with more bulky substituent in the m-position at aromatic ring in the hydrophilic part of molecule.

A New Triterpenoid Alkaloid from Buxus sempervirens

2011 ◽  
Vol 66 (10) ◽  
pp. 1076-1078 ◽  
Author(s):  
Yu-Xin Yan ◽  
Yun Sun ◽  
Jian-Chao Chen ◽  
Jia Su ◽  
Yan Li ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Spectral Data ◽  
Human Cell ◽  
Spectral Methods ◽  
Inhibitory Activity ◽  
Human Cell Lines ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Buxus Sempervirens ◽  
Mcf 7

A new triterpenoid alkaloid, 16-deacetoxy-hyrcamine (1), together with six analogs, was isolated from the leaves and stems of Buxus sempervirens. Their structures were elucidated based on spectral methods and by comparison of the spectral data with those reported previously. All isolated compounds were evaluated for their growth inhibitory activity against human cell lines HL-60, SMMC-7721, A-549,MCF-7, and SW480. Compounds 1 - 4 and 6 showed modest cytotoxic activity against A-549, MCF-7, and SW480.

Decoration of specific sites on freeze-fractured membranes

1978 ◽  
Vol 36 (2) ◽  
pp. 140-141
Author(s):  
H. Gross ◽  
H. Moor
Keyword(s):  
Pure Water ◽  
Freeze Fracture ◽  
Chemical Properties ◽  
Surface Forces ◽  
Sulfate Pentahydrate ◽  
Copper Sulfate Pentahydrate ◽  
Physico Chemical ◽  
Water Of Hydration ◽  
Small Container ◽  
Binding Forces

Fracturing under ultrahigh vacuum (UHV, p ≤ 10-9 Torr) produces membrane fracture faces devoid of contamination. Such clean surfaces are a prerequisite foe studies of interactions between condensing molecules is possible and surface forces are unequally distributed, the condensate will accumulate at places with high binding forces; crystallites will arise which may be useful a probes for surface sites with specific physico-chemical properties. Specific “decoration” with crystallites can be achieved nby exposing membrane fracture faces to water vopour. A device was developed which enables the production of pure water vapour and the controlled variation of its partial pressure in an UHV freeze-fracture apparatus (Fig.1a). Under vaccum (≤ 10-3 Torr), small container filled with copper-sulfate-pentahydrate is heated with a heating coil, with the temperature controlled by means of a thermocouple. The water of hydration thereby released enters a storage vessel.

Activation of cytochrome c to a peroxidase compound I-type intermediate by H2O2: relevance to redox signalling in apoptosis

2004 ◽  
Vol 71 ◽  
pp. 97-106 ◽  
Author(s):  
Mark Burkitt ◽  
Clare Jones ◽  
Andrew Lawrence ◽  
Peter Wardman
Keyword(s):  
Cytochrome C ◽  
Hydroxyl Radical ◽  
Redox Regulation ◽  
Chemotherapeutic Agents ◽  
Tyrosyl Radical ◽  
Compound I ◽  
Definitive Evidence ◽  
Enhanced Production ◽  
Physico Chemical

The release of cytochrome c from mitochondria during apoptosis results in the enhanced production of superoxide radicals, which are converted to H2O2 by Mn-superoxide dismutase. We have been concerned with the role of cytochrome c/H2O2 in the induction of oxidative stress during apoptosis. Our initial studies showed that cytochrome c is a potent catalyst of 2′,7′-dichlorofluorescin oxidation, thereby explaining the increased rate of production of the fluorophore 2′,7′-dichlorofluorescein in apoptotic cells. Although it has been speculated that the oxidizing species may be a ferryl-haem intermediate, no definitive evidence for the formation of such a species has been reported. Alternatively, it is possible that the hydroxyl radical may be generated, as seen in the reaction of certain iron chelates with H2O2. By examining the effects of radical scavengers on 2′,7′-dichlorofluorescin oxidation by cytochrome c/H2O2, together with complementary EPR studies, we have demonstrated that the hydroxyl radical is not generated. Our findings point, instead, to the formation of a peroxidase compound I species, with one oxidizing equivalent present as an oxo-ferryl haem intermediate and the other as the tyrosyl radical identified by Barr and colleagues [Barr, Gunther, Deterding, Tomer and Mason (1996) J. Biol. Chem. 271, 15498-15503]. Studies with spin traps indicated that the oxo-ferryl haem is the active oxidant. These findings provide a physico-chemical basis for the redox changes that occur during apoptosis. Excessive changes (possibly catalysed by cytochrome c) may have implications for the redox regulation of cell death, including the sensitivity of tumour cells to chemotherapeutic agents.

Freeze-Dried Matrices for Buccal Administration of Propranolol in Children: Physico-Chemical and Functional Characterization

2020 ◽  
Author(s):  
Angela Abruzzo ◽  
Alessandra Crispini ◽  
Cecilia Prata ◽  
Rosanna Adduci ◽  
Fiore Pasquale Nicoletta ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Physico Chemical ◽  
Freeze Dried
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