Alkaline hydrolysis of pivalic esters of ethylene glycol in water-acetone solutions

1980 ◽  
Vol 45 (3) ◽  
pp. 720-726 ◽  
Author(s):  
Stanislav Ševčík ◽  
Miroslav Kubín ◽  
Jiří Štamberg
Keyword(s):  
Ethylene Glycol ◽  
Alkaline Hydrolysis ◽  
Structural Unit ◽  
Hydroxyethyl Methacrylate ◽  
Structural Units ◽  
Kinetics Of Hydrolysis ◽  
Ethylene Dimethacrylate ◽  
Crosslinking Site ◽  
Kinetics Of ◽  
Hydrolysis Of

The paper reports alkaline hydrolysis of ethylene dipivalate and 2-hydroxyethyl pivalates as compounds modelling the structural unit and crosslinking site of hydrophilic gels, i.e. copolymers of 2-hydroxyethyl methacrylate and ethylene dimethacrylate. The kinetics of hydrolysis was investigated in water-acetone solutions containing respectively 50, 75, 80, 85 and 90% by vol. (related to 20°C) of acetone at 20, 30, 40, and 50°C. It was demonstrated that, owing to steric hindrance, the preferential hydrolysis of monoester was more pronounced in the case of pivalic esters of ethylene glycol compared with acetic esters of ethylene glycol. The results are discussed in connection with the selectivity of the alkaline hydrolysis of ester bonds in "pendant" parts of structural units in hydrophylic methacrylate gels.

scholarly journals Isothermal and non-isothermal kinetics of hydrolysis of 1-[2-(2- pentyloxyphenylcarbamoyloxy)-(2-methoxymethyl)-ethyl]- perhydroazepinium chloride (BK 129)

2013 ◽  
Vol 60 (2) ◽  
pp. 43-48
Author(s):  
Stankovičová M. ◽  
Bezáková Ž. ◽  
Beňo P. ◽  
Húšťavová P.
Keyword(s):  
Biological Activity ◽  
Alkaline Hydrolysis ◽  
Functional Group ◽  
Isothermal Kinetics ◽  
Basic Part ◽  
Buffer Solutions ◽  
Kinetics Of Hydrolysis ◽  
Short Time ◽  
Kinetics Of ◽  
Hydrolysis Of

Abstract The substance BK 129 - 1-[2-(2-pentyloxyphenylcarbamoyloxy)-(2-methoxymethyl)-ethyl]-perhydroazepinium chloride was prepared in terms of influence of the connecting chain between the carbamate functional group and the basic part of molecule on biological activity. Such a structural feature is important with regard to its stability. In this work we determined the rate constants of alkaline hydrolysis of this compound at increased temperature under isothermal and non-isothermal conditions. The hydrolysis was also performed in buffer solutions with the purpose of evaluating its stability. Non-isothermal tests of stability enable to reduce the number of analyses. The necessary data for stability of compound are in this way achieved in a short time.

Quaternary salts of N,N-dimethylaminoethyl esters of pivalic and 2-methyl-3-methoxypropionic acid and their hydrolysis

1986 ◽  
Vol 51 (1) ◽  
pp. 206-214 ◽  
Author(s):  
Stanislav Ševčík ◽  
Martin Přádný
Keyword(s):  
Methyl Iodide ◽  
Alkaline Hydrolysis ◽  
Structural Unit ◽  
Model Compounds ◽  
Dimethylaminoethyl Methacrylate ◽  
Quaternary Salts ◽  
Terminal Unit ◽  
Kinetics Of ◽  
Hydrolysis Of

The synthesis and kinetics of quaternization of model compounds of poly(N,N-dimethylaminoethyl methacrylate) in water-alcoholic solutions brought about by methyl iodide and the alkaline hydrolysis of products in water have been investigated. N,N-Dimethylaminoethyl pivalate was selected as a model of the structural unit of the reported polymer; N,N-dimethylaminoethyl-2-methyl-3-methoxypropionate was the model of the terminal unit of the anionically prepared polymer.

Alkaline hydrolysis of methyl hydrogen malonate in water-organic solvents

1986 ◽  
Vol 51 (6) ◽  
pp. 1187-1194 ◽  
Author(s):  
Oľga Grančičová ◽  
Vladislav Holba ◽  
Ľudmila Beluská
Keyword(s):  
Experimental Data ◽  
Ethylene Glycol ◽  
Alkaline Hydrolysis ◽  
Transfer Functions ◽  
Butyl Alcohol ◽  
Gibbs Energies ◽  
Tert Butyl Alcohol ◽  
Kinetics Of ◽  
Hydrolysis Of ◽  
Activated Complex

Kinetics of alkaline hydrolysis of methyl hydrogen malonate in water-methanol, water-dioxane, water-tert-butyl alcohol and water-ethylene glycol mixtures was examined. The valuse of the transfer functions of the activated complex δmμ≠ from water to the first two mixed media were calculated from the measured solubilities of tetrabutylammonium hydrogen malonate, the activation Gibbs energies and the known values of transfer functions for tetrabutylammonium and hydroxide ions. Some conclusions concerning the effect of a nonaqueous component of the solvent on solvation of the reactants and the activated complex have been drawn from the experimental data obtained.

Influence of medium on alkaline hydrolysis of succinic acid monomethyl and monopropyl esters

1980 ◽  
Vol 45 (11) ◽  
pp. 2873-2882
Author(s):  
Vladislav Holba ◽  
Ján Benko
Keyword(s):  
Succinic Acid ◽  
Kinetic Parameters ◽  
Alkaline Hydrolysis ◽  
Specific Interactions ◽  
Nonaqueous Media ◽  
The Media ◽  
Kinetics Of ◽  
Hydrolysis Of

The kinetics of alkaline hydrolysis of succinic acid monomethyl and monopropyl esters were studied in mixed aqueous-nonaqueous media at various temperatures and ionic strengths. The results of measurements are discussed in terms of electrostatic and specific interactions between the reactants and other components of the reaction mixture. The kinetic parameters in the media under study are related to the influence of the cosolvent on the solvation sphere of the reactants.

Kinetics of hydrolysis of peroxodisulphate ions in acidic medium to peroxomonosulphuric acid

1981 ◽  
Vol 46 (5) ◽  
pp. 1229-1236 ◽  
Author(s):  
Jan Balej ◽  
Milada Thumová
Keyword(s):  
Ionic Strength ◽  
Rate Constants ◽  
Acidic Medium ◽  
Measured Data ◽  
Molar Ratios ◽  
Starting Solution ◽  
Kinetics Of Hydrolysis ◽  
Rate Of Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of

The rate of hydrolysis of S2O82- ions in acidic medium to peroxomonosulphuric acid was measured at 20 and 30 °C. The composition of the starting solution corresponded to the anolyte flowing out from an electrolyser for production of this acid or its ammonium salt at various degrees of conversion and starting molar ratios of sulphuric acid to ammonium sulphate. The measured data served to calculate the rate constants at both temperatures on the basis of the earlier proposed mechanism of the hydrolysis, and their dependence on the ionic strength was studied.

The Kinetics of the Acidic and Alkaline Hydrolysis of Ethyl Thionbenzoate

1963 ◽  
Vol 28 (10) ◽  
pp. 2825-2828 ◽  
Author(s):  
Stanley G. Smith ◽  
Marion O'Leary
Keyword(s):  
Alkaline Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of
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