Synthesis of oxytocin analogues modified in the tripeptide side-chain by condensation of aminoterminal linear hexapeptide with the carboxyterminal tripeptide

1979 ◽  
Vol 44 (1) ◽  
pp. 275-287 ◽  
Author(s):  
Jan Hlaváček ◽  
Tomislav Barth ◽  
Karel Bláha ◽  
Karel Jošt
Keyword(s):  
Methyl Ester ◽  
Side Chain ◽  
Glycine Methyl Ester

For the synthesis of oxytocin (Ia) analogues modified in the carboxyterminal part of the molecule, a method based on the condensation of protected aminoterminal hexapeptide with tripeptides by the action of dicyclohexylcarbodiimide and pentafluorophenol in the presence of 1-hydroxybenzotriazole was devised. Using this method [7-[U-13C]proline]oxytocin (Ib), des-9-glycine-oxytocin (Ic) and methyl ester of oxytocinoic acid ([9-glycine methyl ester]oxytocin) (Id) were prepared.

scholarly journals Inactivation of chicken muscle enolase by carbodiimide and glycine methyl ester

FEBS Letters ◽  
1982 ◽  
Vol 143 (2) ◽  
pp. 211-212 ◽  
Author(s):  
Gillian A. Russell ◽  
Linda A. Fothergill
Keyword(s):  
Methyl Ester ◽  
Chicken Muscle ◽  
Glycine Methyl Ester

C3H7NO2 Glycine methyl ester

2005 ◽  
pp. 1-1
Author(s):  
G. Graner ◽  
E. Hirota ◽  
T. Iijima ◽  
K. Kuchitsu ◽  
D. A. Ramsay ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Glycine Methyl Ester

Proso Millet (Panicum miliaceum) Control in Corn (Zea mays) by Postemergence-Directed Herbicides

Weed Science ◽  
1988 ◽  
Vol 36 (2) ◽  
pp. 215-220 ◽  
Author(s):  
James A. Fawcett ◽  
Robert G. Harvey
Keyword(s):  
Zea Mays ◽  
Methyl Ester ◽  
Butyl Ester ◽  
Propanoic Acid ◽  
Panicum Miliaceum ◽  
Proso Millet ◽  
Glycine Methyl Ester

Proso millet (Panicum miliaceumL. # PANMI) was controlled in corn (Zea maysL. ‘Pioneer 3747’) with postemergence-directed herbicides applied following a standard preplant-incorporated application of butylate[S-ethylbis(2-methylpropyl)carbamothioate] plus dichlormid (2,2-dichloro-N,N-di-2-propenylacetamide) plus cyanazine {2-[[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino]-2-methylpropanenitrile}. Postemergence-directed applications of ametryn [N-ethyl-N′-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine], cloproxydim {(E,E)-2-[1-[[(3-chloro-2-propenyl)oxy]imino]butyl]-5-[2-(ethylthio)propyl]-3-hydroxy-2-cyclohexen-1-one}, butyl ester of fluazifop {(±)-2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy] propanoic acid}, butyl ester of fluazifop-p {(R)-2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy] propanoic acid}, glyphosate [N-(phosphonomethyl)glycine], methyl ester of haloxyfop {2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid}, and sethoxydim {2-[1-(ethoxyimino)butyl]-5-[2-(ethylthio)propyl]-3-hydroxy-2-cyclohexen-1-one} in 40-cm-tall corn gave greater than 90% control of 5- to 15-cm-tall proso millet while causing little or no corn injury at selected rates. Season-long proso millet control was obtained with sethoxydim at rates as low as 56 g ai/ha with no visible corn injury. Unacceptable injury to 40-cm-tall corn occurred with all but the lowest rate of sethoxydim (56 g ai/ha) when a crop oil concentrate was used. Sethoxydim applied as a directed spray at rates up to 110 g ai/ha plus 1.25% (v/v) crop oil concentrate did not injure 60-cm-tall corn.

Amidation of methyl ester side chain bearing poly(2-oxazoline)s with tyramine: a quest for a selective and quantitative approach

2019 ◽  
Vol 10 (8) ◽  
pp. 954-962 ◽  
Author(s):  
Joachim F. R. Van Guyse ◽  
Maarten A. Mees ◽  
Maarten Vergaelen ◽  
Mathijs Baert ◽  
Bart Verbraeken ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Quantitative Approach ◽  
Side Chain

Three new amidation approaches are evaluated to incorporate tyramine on methyl ester functional poly(2-oxazolines).

Volume phase transition induced by temperature sensitive DL-amino acid methyl ester side chain based copolymer gels

2000 ◽  
Vol 3 (3) ◽  
pp. 381-387 ◽  
Author(s):  
Akihiro Hiroki ◽  
Hideaki Iwakami ◽  
Masaru Yoshida ◽  
Takeshi Suwa ◽  
Masaharu Asano ◽  
...  
Keyword(s):  
Phase Transition ◽  
Amino Acid ◽  
Methyl Ester ◽  
Acid Methyl Ester ◽  
Side Chain ◽  
Temperature Sensitive ◽  
Volume Phase Transition ◽  
Volume Phase ◽  
Acid Methyl ◽  
Amino Acid Methyl Ester

scholarly journals Cover Feature: Making Glycine Methyl Ester Chiral (Chem. Eur. J. 46/2018)

2018 ◽  
Vol 24 (46) ◽  
pp. 11808-11808
Author(s):  
Dennis Gerbig ◽  
Sarina Desch ◽  
Peter R. Schreiner
Keyword(s):  
Methyl Ester ◽  
Glycine Methyl Ester

The Inactivation of Penicillopepsin with l,2-Epoxy-3-(p-nitrophenoxy)propane, an Active-Site Directed Reagent

1974 ◽  
Vol 52 (11) ◽  
pp. 1018-1023 ◽  
Author(s):  
G. Mains ◽  
T. Hofmann
Keyword(s):  
Methyl Ester ◽  
Aspartic Acid ◽  
Active Site ◽  
Side Chain ◽  
Porcine Pepsin ◽  
Protein Inactivation ◽  
Pepsin Inhibitor

Penicillopepsin was fully inactivated by the pepsin inhibitor 1,2-epoxy-3-(p-nitrophenoxy) propane, and 1.3 ± 0.3 mol of reagent became associated with each mole of protein. Inactivation was more rapid at pH 3.0 than at pH 6.0. Approximately 1 equivalent of the bound reagent was esterified to an aspartic acid side chain. Enzyme previously inactivated with diazoacetylnorleucine methyl ester did not react with the epoxide; and enzyme that was first inactivated with the epoxide did not react with the diazo inhibitor. The results add further evidence for the enzymatic similarity of porcine pepsin and penicillopepsin.

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