Kinetics and mechanism of diazo coupling. XVI. Coupling reactions of benzenediazonium salts with aniline and their decomposition reactions

1970 ◽  
Vol 35 (11) ◽  
pp. 3402-3409 ◽  
Author(s):  
V. Beránek ◽  
M. Večeřa
Keyword(s):  
Kinetics And Mechanism ◽  
Coupling Reactions ◽  
Decomposition Reactions ◽  
Diazo Coupling

scholarly journals New Diazo Coupling Reactions for Visible Spectrophotometric Determination of Alfuzosin in Pharmaceutical Preparations

2007 ◽  
Vol 4 (4) ◽  
pp. 496-501 ◽  
Author(s):  
M. Vamsi Krishna ◽  
D. Gowri Sankar
Keyword(s):  
Pharmaceutical Preparations ◽  
Pharmaceutical Formulations ◽  
Molar Absorptivity ◽  
Basic Medium ◽  
Coupling Reactions ◽  
Acetyl Acetone ◽  
Diazo Coupling ◽  
Optimum Reaction ◽  
Diazonium Ion

Simple, rapid and sensitive spectrophotometric procedures were developed for the analysis of Alfuzosin hydrochloride (AFZ) in pure form as well as in pharmaceutical formulations. The methods are based on the reaction of AFZ with nitrite in acid medium to form diazonium ion, which is coupled with ethoxyethylenemaleic ester (Method A) or ethylcyanoacetate (Method B) or acetyl acetone (method C) in basic medium to form azo dyes, showing absorption maxima at 440, 465 and 490 nm respectively. Beer’s law is obeyed in the concentration of 4-20 μg/mL of AFZ for methods A, B and 3-15 μg/mL of AFZ for method C. The molar absorptivity and sandell’s sensitivity of AFZ- ethoxyethylenemaleic ester, AFZ- ethylcyanoacetate and AFZ-acetyl acetone are1.90 × 104, 0.022; 1.93 × 104, 0.021 and 2.67 × 104L mole-1cm-1, 0.015 μg cm-2respectively. The optimum reaction conditions and other analytical parameters were evaluated. The methods were successfully applied to the determination of AFZ in pharmaceutical formulations.

ChemInform Abstract: THE ACTIVATING EFFECTS OF AMINO GROUPS IN DIAZO-COUPLING REACTIONS

1974 ◽  
Vol 5 (20) ◽  
pp. no-no
Author(s):  
YOJI HASHIDA ◽  
JUNICHI TAKENAKA ◽  
KOHJI MATSUI
Keyword(s):  
Coupling Reactions ◽  
Amino Groups ◽  
Diazo Coupling

Rapid and efficient diazotization and diazo coupling reactions on silica sulfuric acid under solvent-free conditions

2009 ◽  
Vol 81 (3) ◽  
pp. 240-244 ◽  
Author(s):  
A ZAREI ◽  
A HAJIPOUR ◽  
L KHAZDOOZ ◽  
B MIRJALILI ◽  
A NAJAFICHERMAHINI
Keyword(s):  
Sulfuric Acid ◽  
Solvent Free ◽  
Coupling Reactions ◽  
Silica Sulfuric Acid ◽  
Solvent Free Conditions ◽  
Diazo Coupling
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