Amino acids and peptides. XCIII. Application of the Hammett equation to the optical rotation of substituted β-phenylalanines

1969 ◽  
Vol 34 (9) ◽  
pp. 2852-2856 ◽  
Author(s):  
K. Bláha ◽  
I. Frič
Keyword(s):  
Amino Acids ◽  
Optical Rotation ◽  
Hammett Equation

Homochirality as the Signature of Extra-Terrestrial Life

1997 ◽  
Vol 161 ◽  
pp. 505-510
Author(s):  
Alexandra J. MacDermott ◽  
Laurence D. Barron ◽  
Andrè Brack ◽  
Thomas Buhse ◽  
John R. Cronin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Protein Synthesis ◽  
Optical Rotation ◽  
Physical Origin ◽  
Natural Choice ◽  
Rosetta Mission ◽  
Terrestrial Life ◽  
Subsurface Layers ◽  
Solar System Bodies ◽  
Origin Of Homochirality

AbstractThe most characteristic hallmark of life is its homochirality: all biomolecules are usually of one hand, e.g. on Earth life uses only L-amino acids for protein synthesis and not their D mirror images. We therefore suggest that a search for extra-terrestrial life can be approached as a Search for Extra- Terrestrial Homochirality (SETH). The natural choice for a SETH instrument is optical rotation, and we describe a novel miniaturized space polarimeter, called the SETH Cigar, which could be used to detect optical rotation as the homochiral signature of life on other planets. Moving parts are avoided by replacing the normal rotating polarizer by multiple fixed polarizers at different angles as in the eye of the bee. We believe that homochirality may be found in the subsurface layers on Mars as a relic of extinct life, and on other solar system bodies as a sign of advanced pre-biotic chemistry. We discuss the chiral GC-MS planned for the Roland lander of the Rosetta mission to a comet and conclude with theories of the physical origin of homochirality.

Lemon Juice Composition. I. Characterization of California-Arizona Lemon Juice by Its Total Amino Acid and l-Malic Acid Content

1963 ◽  
Vol 46 (3) ◽  
pp. 353-358 ◽  
Author(s):  
Carl E Vandercook ◽  
Laurence A Rolle ◽  
Robert M Ikeda
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Malic Acid ◽  
Acid Content ◽  
Optical Rotation ◽  
Lemon Juice ◽  
Total Amino Acid ◽  
The Individual ◽  
Composition I ◽  
Total Amino Acids

Abstract The total amino acid and i-malic acid content of 61 samples of commercial California-Arizona lemon juice and lemon juice concentrates were studied. In characterizing these juices, relationships were observed between the natural citric acid content and the amounts of their total amino acids and l-malic acid. Total amino acids were determined by formol titration, while the l-malic acid was determined by measuring the optical rotation of a uranylmalate complex. Paper chromatograms of the individual amino acids are used to supplement these methods of analysis for characterizing lemon juice.

Specific Anion Effects on the Optical Rotation of α-Amino Acids

2007 ◽  
Vol 111 (35) ◽  
pp. 10510-10519 ◽  
Author(s):  
Simona Rossi ◽  
Pierandrea Lo Nostro ◽  
Marco Lagi ◽  
Barry W. Ninham ◽  
Piero Baglioni
Keyword(s):  
Amino Acids ◽  
Optical Rotation

Amino acids and peptides. VIII. The synthesis and some properties of L-cystine diamide

1962 ◽  
Vol 15 (1) ◽  
pp. 106 ◽  
Author(s):  
IW Stapleton ◽  
JM Swan
Keyword(s):  
Amino Acids ◽  
Optical Rotation ◽  
Molecular Rotation ◽  
Amino Groups ◽  
Polarographic Behaviour ◽  
Ionizable Groups

L-Cystine diamide has been synthesized by several different routes and isolated as its crystalline di(trifluor0acetate) and dihydrochloride. The compound has a molecular rotation [M]D21 -630� in 1N HCl, compared to [M]D20 -537� for L-cystine ; the rotation is strongly dependent on pH in the range 5-8, the value of [M]D20 at pH 8 being -120�. The polarographic behaviour of L-cystine diamide is very similar to that of cystine. The amino groups in cystine diamide are only weakly basic, the pK?A values being 5.93 and 6.90 for the successive ionizations of the two NH3+ groups. The latter result is in accordance with the known acigenic properties of both amide and disulphide groups. A possible relation between optical rotation of cystine compounds and the pK? values of ionizable groups present in the molecule is discussed.

scholarly journals Mechanism of Optical Rotation of Amino Acids Using Electronic State Calculation

2020 ◽  
Vol 835 ◽  
pp. 012020
Author(s):  
Shuichi Katsumoto ◽  
Manami Mimura ◽  
Tomohiko Ishii ◽  
Genta Sakane ◽  
Kazuyoshi Ogasawara
Keyword(s):  
Amino Acids ◽  
Electronic State ◽  
Optical Rotation ◽  
State Calculation
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