Asymmetric reactions. XXIX. Absolute configuration of ω-phenyl-2-alkylamines and their N-methyl derivatives

1968 ◽  
Vol 33 (11) ◽  
pp. 3551-3557 ◽  
Author(s):  
O. Červinka ◽  
E. Kroupová ◽  
O. Bělovský
Keyword(s):  
Absolute Configuration ◽  
Asymmetric Reactions ◽  
Methyl Derivatives

Preparation and absolute configuration at C(22) of 21,26,27-trinor-5α-cholestan-25→22-olide derivatives

1985 ◽  
Vol 50 (4) ◽  
pp. 869-877 ◽  
Author(s):  
Vladimír Pouzar ◽  
Pavel Drašar ◽  
Ivan Černý ◽  
Miroslav Havel
Keyword(s):  
Absolute Configuration ◽  
Side Chain ◽  
Cd Spectra ◽  
Methyl Derivatives

Epimeric 21,26,27-trinor-5α-cholestan-25→22-olides (X and XVII), 21,26,27-trinor-5α-cholest-23-en-25→22-olides (XV and XXII), and their 23-methyl derivatives XVI and XXIII were prepared by lengthening the side chain in 5α-pregnan-21-al (I). On the basis of CD spectra and chemical correlations with 21,26,27-trinor-5α-cholestane-22,25-diols, the configuration 22S was ascribed to lactones X, XXII and XXIII whereas lactones XV, XVI and XVII were assigned the 22R configuration.

Sign in / Sign up

Export Citation Format

Share Document