Effect of acoustic nonlinearity on heating of biological tissue by high-intensity focused ultrasound

2001 ◽  
Vol 47 (4) ◽  
pp. 468-475 ◽  
Author(s):  
E. A. Filonenko ◽  
V. A. Khokhlova
Keyword(s):  
Biological Tissue ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Acoustic Nonlinearity

scholarly journals The role of acoustic nonlinearity in tissue heating behind a rib cage using a high-intensity focused ultrasound phased array

2013 ◽  
Vol 58 (8) ◽  
pp. 2537-2559 ◽  
Author(s):  
Petr V Yuldashev ◽  
Svetlana M Shmeleva ◽  
Sergey A Ilyin ◽  
Oleg A Sapozhnikov ◽  
Leonid R Gavrilov ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Phased Array ◽  
High Intensity Focused Ultrasound ◽  
Rib Cage ◽  
Acoustic Nonlinearity ◽  
Tissue Heating

High-Intensity Focused Ultrasound: Heating and Destruction of Biological Tissue

2020 ◽  
Vol 65 (9) ◽  
pp. 1455-1466 ◽  
Author(s):  
T. A. Andreeva ◽  
A. E. Berkovich ◽  
N. Y. Bykov ◽  
S. V. Kozyrev ◽  
A. Ya. Lukin
Keyword(s):  
Biological Tissue ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound

Nonlinear absorption in biological tissue for high intensity focused ultrasound

Ultrasonics ◽  
2006 ◽  
Vol 44 ◽  
pp. e27-e30 ◽  
Author(s):  
Xiaozhou Liu ◽  
Junlun Li ◽  
Xiufen Gong ◽  
Dong Zhang
Keyword(s):  
Biological Tissue ◽  
Nonlinear Absorption ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound

scholarly journals Imaging of high-intensity focused ultrasound-induced lesions in soft biological tissue using thermoacoustic tomography

2004 ◽  
Vol 32 (1) ◽  
pp. 5-11 ◽  
Author(s):  
Xing Jin ◽  
Yuan Xu ◽  
Lihong V. Wang ◽  
Yuncai R. Fang ◽  
Claudio I. Zanelli ◽  
...  
Keyword(s):  
Biological Tissue ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Thermoacoustic Tomography ◽  
Soft Biological Tissue

A method for phase aberration correction of high intensity focused ultrasound fields using acoustic nonlinearity

2016 ◽  
Vol 140 (4) ◽  
pp. 3083-3083 ◽  
Author(s):  
Tatiana Khokhlova ◽  
Adam Maxwell ◽  
Wayne Kreider ◽  
Vera Khokhlova ◽  
Matthew O'Donnell ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Aberration Correction ◽  
Phase Aberration ◽  
Acoustic Nonlinearity

scholarly journals Effects of Nonlinear Propagation of Focused Ultrasound on the Stable Cavitation of a Single Bubble

Acoustics ◽  
2018 ◽  
Vol 1 (1) ◽  
pp. 14-34 ◽  
Author(s):  
Marjan Bakhtiari-Nejad ◽  
Shima Shahab
Keyword(s):  
Acoustic Field ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Bubble Dynamics ◽  
Translational Motion ◽  
High Intensity Focused Ultrasound ◽  
Nonlinear Propagation ◽  
Resonance Excitation ◽  
Acoustic Nonlinearity ◽  
Shape Oscillations

Many biomedical applications such as ultrasonic targeted drug delivery, gene therapy, and molecular imaging entail the problems of manipulating microbubbles by means of a high-intensity focused ultrasound (HIFU) pressure field; namely stable cavitation. In high-intensity acoustic field, bubbles demonstrate translational instability, the well-known erratic dancing motion, which is caused by shape oscillations of the bubbles that are excited by their volume oscillations. The literature of bubble dynamics in the HIFU field is mainly centered on experiments, lacking a systematic study to determine the threshold for shape oscillations and translational motion. In this work, we extend the existing multiphysics mathematical modeling platform on bubble dynamics for taking account of (1) the liquid compressibility which allows us to apply a high-intensity acoustic field; (2) the mutual interactions of volume pulsation, shape modes, and translational motion; as well as (3) the effects of nonlinearity, diffraction, and absorption of HIFU to incorporate the acoustic nonlinearity due to wave kinematics or medium—all in one model. The effects of acoustic nonlinearity on the radial pulsations, axisymmetric modes of shape oscillations, and translational motion of a bubble, subjected to resonance and off-resonance excitation and various acoustic pressure, are examined. The results reveal the importance of considering all the involved harmonics and wave distortion in the bubble dynamics, to accurately predict the oscillations, translational trajectories, and the threshold for inertial (unstable) cavitation. This result is of interest for understanding the bubble dynamical behaviors observed experimentally in the HIFU field.

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