scholarly journals Prevalence and Genetic Diversity of Hepatitis B and Delta Viruses in Pregnant Women in Gabon: Molecular Evidence that Hepatitis Delta Virus Clade 8 Originates from and Is Endemic in Central Africa

2007 ◽  
Vol 46 (2) ◽  
pp. 754-756 ◽  
Author(s):  
M. Makuwa ◽  
M. Caron ◽  
S. Souquiere ◽  
G. Malonga-Mouelet ◽  
A. Mahe ◽  
...  
2021 ◽  
Author(s):  
Yacouba Foupouapouognigni ◽  
Jacques Delors Mfonkou Toumansie ◽  
Onana Boyomo ◽  
Antoine Gessain ◽  
Richard Njouom

Abstract A single study conducted two decades ago on hepatitis delta virus (HDV) infections among Baka Pygmies in Cameroon reported a very high antibody prevalence of 46%, but HDV genetic diversity has not yet been studied in this remote population. In the present study, we investigated the HDV seroprevalence and the genotype diversity in the three main Cameroonian Pygmy populations with chronic HBV infection. An unusually high (69.2%) level of HDV infection was found among HBsAg-positive Pygmies in Cameroon. Phylogenetic analyses showed the co-circulation of highly diverse HDV genotypes HDV-1 and HDV-7 in this population. These results highlighted the endemicity of HDV infection in Central Africa and suggest an african origin of HDV.


2012 ◽  
Vol 84 (8) ◽  
pp. 1186-1198 ◽  
Author(s):  
Wael Mansour ◽  
F- Zahra Fall Malick ◽  
Ahmad Sidiya ◽  
Elkhalil Ishagh ◽  
Mariama Abdou Chekaraou ◽  
...  

2021 ◽  
pp. 104870
Author(s):  
Boris J.B. Beudeker ◽  
Jolanda J.C. Voermans ◽  
Corine.H. GeurtsvanKessel ◽  
Robert J. de Knegt ◽  
Tamara Kuhlemann ◽  
...  

2021 ◽  
Author(s):  
Kasthuri Prakash ◽  
Simon B. Larsson ◽  
Gustaf E. Rydell ◽  
Johan Ringlander ◽  
Catarina Skoglund ◽  
...  

Digestion ◽  
1993 ◽  
Vol 54 (1) ◽  
pp. 9-14
Author(s):  
Nicola Napoli ◽  
Giorgio Fiore ◽  
Giacomo Fera ◽  
Angela Modugno ◽  
Gianluigi Giannelli ◽  
...  

1993 ◽  
Vol 6 (3) ◽  
pp. 211-229 ◽  
Author(s):  
L B Polish ◽  
M Gallagher ◽  
H A Fields ◽  
S C Hadler

Hepatitis delta virus, discovered in 1977, requires the help of hepatitis B virus to replicate in hepatocytes and is an important cause of acute, fulminant, and chronic liver disease in many regions of the world. Because of the helper function of hepatitis delta virus, infection with it occurs either as a coinfection with hepatitis B or as a superinfection of a carrier of hepatitis B surface antigen. Although the mechanisms of transmission are similar to those of hepatitis B virus, the patterns of transmission of delta virus vary widely around the world. In regions of the world in which hepatitis delta virus infection is not endemic, the disease is confined to groups at high risk of acquiring hepatitis B infection and high-risk hepatitis B carriers. Because of the propensity of this viral infection to cause fulminant as well as chronic liver disease, continued incursion of hepatitis delta virus into areas of the world where persistent hepatitis B infection is endemic will have serious implications. Prevention depends on the widespread use of hepatitis B vaccine. This review focuses on the molecular biology and the clinical and epidemiologic features of this important viral infection.


PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0175304 ◽  
Author(s):  
Hung Minh Nguyen ◽  
Bui Tien Sy ◽  
Nguyen Thanh Trung ◽  
Nghiem Xuan Hoan ◽  
Heiner Wedemeyer ◽  
...  

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