scholarly journals First Report of Liver Abscess Caused by Salmonella enterica Serovar Dublin

2013 ◽  
Vol 51 (9) ◽  
pp. 3140-3142 ◽  
Author(s):  
F. Qu ◽  
Z. Fan ◽  
E. Cui ◽  
W. Zhang ◽  
C. Bao ◽  
...  
2019 ◽  
Vol 93 (4) ◽  
pp. 376-379 ◽  
Author(s):  
Luisa Z. Moreno ◽  
Vasco T.M. Gomes ◽  
Jéssica Moreira ◽  
Carolina H. de Oliveira ◽  
Bárbara P. Peres ◽  
...  

2008 ◽  
Vol 13 (32) ◽  
Author(s):  
E D'Ortenzio ◽  
F X Weill ◽  
S Ragonneau ◽  
J A Lebon ◽  
P Renault ◽  
...  

Binary file ES_Abstracts_Final_ECDC.txt matches


2016 ◽  
Vol 22 (2) ◽  
pp. 117-119 ◽  
Author(s):  
Babita Jha ◽  
Choon-Mee Kim ◽  
Dong-Min Kim ◽  
Jong-Hoon Chung ◽  
Na-Ra Yoon ◽  
...  

2019 ◽  
Vol 8 (14) ◽  
Author(s):  
Manal Mohammed ◽  
Marie-Leone Vignaud ◽  
Sabrina Cadel-Six

Here, we report the genome sequences of two Salmonella enterica serovar Dublin strains, 03EB8736SAL and 03EB8994SAL, isolated from raw-milk cheese and milk filtrate, respectively. Analysis of the draft genomes of the two isolates reveals the presence of the viaA, viaB, and ompB loci of the Vi capsular polysaccharide antigen (Vi antigen).


2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Prerna Vohra ◽  
Christina Vrettou ◽  
Jayne C. Hope ◽  
John Hopkins ◽  
Mark P. Stevens

AbstractSalmonella enterica is a veterinary and zoonotic pathogen of global importance. While murine and cell-based models of infection have provided considerable knowledge about the molecular basis of virulence of Salmonella, relatively little is known about salmonellosis in naturally-affected large animal hosts such as cattle, which are a reservoir of human salmonellosis. As in humans, Salmonella causes bovine disease ranging from self-limiting enteritis to systemic typhoid-like disease and exerts significant economic and welfare costs. Understanding the nature and consequences of Salmonella interactions with bovine cells will inform the design of effective vaccines and interventions to control animal and zoonotic infections. In calves challenged orally with S. Dublin expressing green fluorescent protein (GFP) we observed that the bacteria were predominantly extracellular in the distal ileal mucosa and within gut-associated lymph nodes 48 h post-infection. Intracellular bacteria, identified by flow cytometry using the GFP signal, were predominantly within MHCII+ macrophage-like cells. In contrast to observations from murine models, these S. Dublin-infected cells had elevated levels of MHCII and CD40 compared to both uninfected cells from the same tissue and cells from the cognate tissue of uninfected animals. Moreover, no gross changes of the architecture of infected lymph nodes were observed as was described previously in a mouse model. In order to further investigate Salmonella-macrophage interactions, net replication of S. enterica serovars that differ in virulence in cattle was measured in bovine blood-derived macrophages by enumeration of gentamicin-protected bacteria and fluorescence dilution, but did not correlate with host-specificity.


2008 ◽  
Vol 76 (11) ◽  
pp. 5310-5321 ◽  
Author(s):  
Gillian D. Pullinger ◽  
Francis Dziva ◽  
Bryan Charleston ◽  
Timothy S. Wallis ◽  
Mark P. Stevens

ABSTRACTSalmonella entericaserovar Dublin is a host-restricted serovar associated with typhoidal disease in cattle. In contrast, the fowl-associated serovarS. entericaserovar Gallinarum is avirulent in calves, yet it invades ileal mucosa and induces enteritis at levels comparable to those induced byS. entericaserovar Dublin. Suppression subtractive hybridization was employed to identifyS. entericaserovar Dublin strain SD3246 genes absent fromS. entericaserovar Gallinarum strain SG9. Forty-oneS. entericaserovar Dublin fragments were cloned and sequenced. Among these, 24 mobile-element-associated genes were identified, and 12 clones exhibited similarity with sequences of known or predicted function in other serovars. ThreeS. entericaserovar Dublin-specific regions were homologous to regions from the genome ofEnterobactersp. strain 638. Sequencing of fragments adjacent to these three sequences revealed the presence of a 21-kb genomic island, designatedS. entericaserovar Dublin island 1 (SDI-1). PCR analysis and Southern blotting showed that SDI-1 is highly conserved withinS. entericaserovar Dublin isolates but rarely found in other serovars. To probe the role of genes identified by subtractive hybridization in vivo, 24 signature-taggedS. entericaserovar Dublin SD3246 mutants lacking loci not present inSalmonellaserovar Gallinarum SG9 were created and screened by oral challenge of cattle. Though attenuation of tagged SG9 and SD3246Salmonellapathogenicity island-1 (SPI-1) and SPI-2 mutant strains was detected, no obvious defects of these 24 mutants were detected. Subsequently, a ΔSDI-1 mutant was found to exhibit weak but significant attenuation compared with the parent strain in coinfection of calves. SDI-1 mutation did not impair invasion, intramacrophage survival, or virulence in mice, implying that SDI-1 does not influence fitness per se and may act in a host-specific manner.


2019 ◽  
Vol 8 (31) ◽  
Author(s):  
Baha Abdalhamid ◽  
Emily L. Mccutchen ◽  
Kacie D. Flaherty ◽  
Steven H. Hinrichs ◽  
Peter C. Iwen

Salmonella enterica serovar Dublin, which can cause enteritis and systemic infections in humans, has been associated with antimicrobial resistance. Here, we report draft genome sequences of seven multidrug-resistant S. Dublin isolates from human samples. These sequences will contribute to an understanding of pathogenesis and resistance determinants in this serovar.


Sign in / Sign up

Export Citation Format

Share Document