scholarly journals The Rv1712 Locus from Mycobacterium tuberculosis H37Rv Codes for a Functional CMP Kinase That Preferentially Phosphorylates dCMP

2009 ◽  
Vol 191 (8) ◽  
pp. 2884-2887 ◽  
Author(s):  
Caroline Thum ◽  
Cristopher Z. Schneider ◽  
Mario S. Palma ◽  
Diógenes S. Santos ◽  
Luiz A. Basso
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Steady State ◽  
Tuberculosis H37rv ◽  
Mycobacterium Tuberculosis H37rv ◽  
Steady State Kinetics ◽  
Sequential Mechanism

ABSTRACT The Mycobacterium tuberculosis cmk gene, predicted to encode a CMP kinase (CMK), was cloned and expressed, and its product was purified to homogeneity. Steady-state kinetics confirmed that M. tuberculosis CMK is a monomer that preferentially phosphorylates CMP and dCMP by a sequential mechanism. A plausible role for CMK is discussed.

scholarly journals Molecular characterization of secretory proteins Rv3619c and Rv3620c from Mycobacterium tuberculosis H37Rv

FEBS Journal ◽  
2010 ◽  
Vol 278 (2) ◽  
pp. 341-353 ◽  
Author(s):  
Anjum Mahmood ◽  
Shubhra Srivastava ◽  
Sarita Tripathi ◽  
Mairaj Ahmed Ansari ◽  
Mohammad Owais ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Molecular Characterization ◽  
Tuberculosis H37rv ◽  
Secretory Proteins ◽  
Mycobacterium Tuberculosis H37rv

Discovery of new 1,3,5-triazine scaffolds with potent activity against Mycobacterium tuberculosis H37Rv

2010 ◽  
Vol 45 (8) ◽  
pp. 3335-3345 ◽  
Author(s):  
Naresh Sunduru ◽  
Leena Gupta ◽  
Vinita Chaturvedi ◽  
Richa Dwivedi ◽  
Sudhir Sinha ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Tuberculosis H37rv ◽  
Mycobacterium Tuberculosis H37rv

scholarly journals High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv

Tuberculosis ◽  
2012 ◽  
Vol 92 (1) ◽  
pp. 72-83 ◽  
Author(s):  
Robert C. Reynolds ◽  
Subramaniam Ananthan ◽  
Ellen Faaleolea ◽  
Judith V. Hobrath ◽  
Cecil D. Kwong ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
High Throughput ◽  
High Throughput Screening ◽  
Kinase Inhibitor ◽  
Tuberculosis H37rv ◽  
Mycobacterium Tuberculosis H37rv ◽  
Inhibitor Scaffolds

Aptamer inhibits Mycobacterium tuberculosis (H37Rv) invasion of macrophage

2011 ◽  
Vol 39 (3) ◽  
pp. 2157-2162 ◽  
Author(s):  
Fan Chen ◽  
XiaoLian Zhang ◽  
Jing Zhou ◽  
Shengwu Liu ◽  
Junyan Liu
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Tuberculosis H37rv ◽  
Mycobacterium Tuberculosis H37rv

Arabinosylated lipoarabinomannan modulates the impaired cell mediated immune response in Mycobacterium tuberculosis H37Rv infected C57BL/6 mice

2008 ◽  
Vol 10 (4) ◽  
pp. 349-357 ◽  
Author(s):  
Nivedita Majumder ◽  
Surajit Bhattacharjee ◽  
Ranadhir Dey ◽  
Suchandra Bhattacharyya (Majumdar) ◽  
Nishith K. Pal ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Tuberculosis H37rv ◽  
Mycobacterium Tuberculosis H37rv ◽  
Cell Mediated Immune Response
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