scholarly journals Cold Air Plasma To Decontaminate Inanimate Surfaces of the Hospital Environment

2014 ◽  
Vol 80 (6) ◽  
pp. 2004-2010 ◽  
Author(s):  
Orla J. Cahill ◽  
Tânia Claro ◽  
Niall O'Connor ◽  
Anthony A. Cafolla ◽  
Niall T. Stevens ◽  
...  
Keyword(s):  
Present Report ◽  
Bacterial Load ◽  
Hospital Environment ◽  
Clinical Environment ◽  
Air Plasma ◽  
Cold Air ◽  
Multiresistant Bacteria ◽  
Short Period ◽  
Single Jet ◽  
Polypropylene Powder

ABSTRACTThe hospital environment harbors bacteria that may cause health care-associated infections. Microorganisms, such as multiresistant bacteria, can spread around the patient's inanimate environment. Some recently introduced biodecontamination approaches in hospitals have significant limitations due to the toxic nature of the gases and the length of time required for aeration. This study evaluated thein vitrouse of cold air plasma as an efficient alternative to traditional methods of biodecontamination of hospital surfaces. Cultures of methicillin-resistantStaphylococcus aureus(MRSA), vancomycin-resistant enterococci (VRE), extended-spectrum-β-lactamase (ESBL)-producingEscherichia coli, andAcinetobacter baumanniiwere applied to different materials similar to those found in the hospital environment. Artificially contaminated sections of marmoleum, mattress, polypropylene, powder-coated mild steel, and stainless steel were then exposed to a cold air pressure plasma single jet for 30 s, 60 s, and 90 s, operating at approximately 25 W and 12 liters/min flow rate. Direct plasma exposure successfully reduced the bacterial load by log 3 for MRSA, log 2.7 for VRE, log 2 for ESBL-producingE. coli, and log 1.7 forA. baumannii. The present report confirms the efficient antibacterial activity of a cold air plasma single-jet plume on nosocomial bacterially contaminated surfaces over a short period of time and highlights its potential for routine biodecontamination in the clinical environment.

Cold-Air Atmospheric Pressure Plasma Against Clostridium difficile Spores: A Potential Alternative for the Decontamination of Hospital Inanimate Surfaces

2015 ◽  
Vol 36 (6) ◽  
pp. 742-744 ◽  
Author(s):  
Tânia Claro ◽  
Orla J. Cahill ◽  
Niall O’Connor ◽  
Stephen Daniels ◽  
Hilary Humphreys
Keyword(s):  
Clostridium Difficile ◽  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasma ◽  
Infect Control Hosp ◽  
Air Plasma ◽  
Cold Air ◽  
Pressure Plasma ◽  
Environmental Surfaces ◽  
Potential Alternative ◽  
Single Jet

AbstractClostridium difficile spores survive for months on environmental surfaces and are highly resistant to decontamination. We evaluated the effect of cold-air plasma against C. difficile spores. The single-jet had no effect while the multi-jet achieved 2–3 log10 reductions in spore counts and may augment traditional decontamination.Infect Control Hosp Epidemiol 2015;00(0):1–3

scholarly journals Clinical and microbiological evaluation of one-stage full-mouth disinfection: a short-term study

2013 ◽  
Vol 42 (4) ◽  
pp. 298-303
Author(s):  
José Roberto Cortelli ◽  
Marcos Vinicius Moreira de Castro ◽  
Rodrigo Dalla Pria Balejo ◽  
Camila Oliveira de Alencar ◽  
Antonio Carlos Gargioni Filho ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Bacterial Load ◽  
Periodontal Treatment ◽  
Periodontal Pocket ◽  
Short Term ◽  
Term Study ◽  
One Stage ◽  
Short Term Study ◽  
Short Period ◽  
Full Mouth Disinfection

INTRODUCTION: Patients seem to adhere better to short-term periodontal treatment schemes. Besides, time-reduced treatments are more cost-effective. However, the degree of benefits related to this type of treatment still requires additional investigations. AIM: The present short-term study evaluated clinical and microbiological outcomes, from baseline to 3-months, of chronic periodontitis subjects treated by the one-stage full-mouth disinfection protocol. MATERIAL AND METHOD: Sixteen chronic periodontitis subjects (mean-age 49.87 ± 8.22) who met inclusion/exclusion criteria were included. A calibrated examiner measured whole-mouth plaque and gingival indices, periodontal pocket depth and clinical attachment level at baseline and at 3-months. Subgingival samples were also collected from the 5 most diseased periodontal sites to determine total bacterial load and levels of P. gingivalis and S. oralis by real time qPCR. Periodontal treatment consisted of full-mouth manual debridement plus wide intraoral use of chlorhexidine in gel and solution. Additionally, after debridement, individuals rinsed 0.12% chlorhexidine at home twice a day for the following 2 months. Data monitored were compared by paired Student-t test (p<0.05). RESULT: Statistical analysis revealed that, in general, one-stage full-mouth disinfection treatment provided significant clinical and microbiological improvements at 3-months. Total bacterial load showed one of the most pronounced reductions from baseline to 3-months (p=0.0001). Also, subgingival levels P. gingivalis and S. oralis reduced overtime. CONCLUSION: After a short period of monitoring, chronic periodontitis subjects showed clinical and microbial improvements following one-stage full-mouth disinfection treatment.

Fluorescence measurements of peroxynitrite/peroxynitrous acid in cold air plasma treated aqueous solutions

2019 ◽  
Vol 21 (17) ◽  
pp. 8883-8896 ◽  
Author(s):  
Barbora Tarabová ◽  
Petr Lukeš ◽  
Malte U. Hammer ◽  
Helena Jablonowski ◽  
Thomas von Woedtke ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Chemical Kinetics ◽  
Fluorescence Detection ◽  
Peroxynitrous Acid ◽  
Air Plasma ◽  
Cold Air ◽  
Fluorescence Measurements ◽  
Direct Fluorescence ◽  
Kinetics Of

The first study providing direct fluorescence detection of peroxynitrite/peroxynitrous acid (ONOO−/ONOOH) in plasma activated liquids correlated with the chemical kinetics of ONOOH formation.

scholarly journals Systemic Antibacterial Activity of Novel Synthetic Cyclic Peptides

2005 ◽  
Vol 49 (8) ◽  
pp. 3302-3310 ◽  
Author(s):  
Véronique Dartois ◽  
Jorge Sanchez-Quesada ◽  
Edelmira Cabezas ◽  
Ellen Chi ◽  
Chad Dubbelde ◽  
...  
Keyword(s):  
Cyclic Peptides ◽  
Prolonged Exposure ◽  
Cyclic Peptide ◽  
Present Report ◽  
Bacterial Load ◽  
Pharmacokinetic Profile ◽  
Therapeutic Window ◽  
Infection Model

ABSTRACT Cyclic peptides with an even number of alternating d,l-α-amino acid residues are known to self-assemble into organic nanotubes. Such peptides previously have been shown to be stable upon protease treatment, membrane active, and bactericidal and to exert antimicrobial activity against Staphylococcus aureus and other gram-positive bacteria. The present report describes the in vitro and in vivo pharmacology of selected members of this cyclic peptide family. The intravenous (i.v.) efficacy of six compounds with MICs of less than 12 μg/ml was tested in peritonitis and neutropenic-mouse thigh infection models. Four of the six peptides were efficacious in vivo, with 50% effective doses in the peritonitis model ranging between 4.0 and 6.7 mg/kg against methicillin-sensitive S. aureus (MSSA). In the thigh infection model, the four peptides reduced the bacterial load 2.1 to 3.0 log units following administration of an 8-mg/kg i.v. dose. Activity against methicillin-resistant S. aureus was similar to MSSA. The murine pharmacokinetic profile of each compound was determined following i.v. bolus injection. Interestingly, those compounds with poor efficacy in vivo displayed a significantly lower maximum concentration of the drug in serum and a higher volume of distribution at steady state than compounds with good therapeutic properties. S. aureus was unable to easily develop spontaneous resistance upon prolonged exposure to the peptides at sublethal concentrations, in agreement with the proposed interaction with multiple components of the bacterial membrane canopy. Although additional structure-activity relationship studies are required to improve the therapeutic window of this class of antimicrobial peptides, our results suggest that these amphipathic cyclic d,l-α-peptides have potential for systemic administration and treatment of otherwise antibiotic-resistant infections.

scholarly journals Change of tension state of electrolytic nickel under exposure to plasma

2021 ◽  
pp. 82-89
Author(s):  
Anna G. Anisovich
Keyword(s):  
Structural Studies ◽  
Air Plasma ◽  
Plasma Exposure ◽  
Initial State ◽  
Cold Air ◽  
X Ray ◽  
Electrolytic Nickel ◽  
Compressive Stresses ◽  
Tension State ◽  
Nickel Grade

A study of the effect of cold air plasma on cathode nickel grade N-1 has been carried out. The changes in the microstructure, macro- and microstresses, as well as static displacements of atoms from equilibrium positions are investigated. By the method of aim metallography it was shown that the microstructure does not change under plasma exposure. X-ray structural studies have established that the level of microstresses does not change when exposed to plasma. A decrease in the magnitude of macrostresses is shown when exposed to plasma for 5 and 10 min. Macrostresses in this case vary from tensile stresses in the initial state to compressive stresses after exposure to plasma. The change in the static displacements of atoms from the equilibrium positions and their decrease when exposed to plasma have been established.

Variation in the Stress State of Copper Alloys Under the Action of Cold Air Plasma

2020 ◽  
Vol 93 (6) ◽  
pp. 1583-1590
Author(s):  
A. G. Anisovich ◽  
I. I. Filatova ◽  
S. V. Goncharik
Keyword(s):  
Stress State ◽  
Copper Alloys ◽  
Air Plasma ◽  
Cold Air

scholarly journals High voltage atmospheric cold air plasma control of bacterial biofilms on fresh produce

2019 ◽  
Vol 293 ◽  
pp. 137-145 ◽  
Author(s):  
Apurva Patange ◽  
D. Boehm ◽  
Dana Ziuzina ◽  
P.J. Cullen ◽  
Brendan Gilmore ◽  
...  
Keyword(s):  
High Voltage ◽  
Fresh Produce ◽  
Bacterial Biofilms ◽  
Air Plasma ◽  
Cold Air ◽  
Plasma Control

scholarly journals PERBEDAAN TINGKAT STRES MAHASISWA PRAKTIK KLINIK PADA TINGKAT II DAN III PROGRAM STUDI D-III KEPERAWATAN STIKES KEPANJEN

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Qori Fanani
Keyword(s):  
Clinical Practice ◽  
Nursing Students ◽  
Nursing Student ◽  
Hospital Environment ◽  
Comparative Approach ◽  
Clinical Learning ◽  
Clinical Environment ◽  
Knowledge And Skills ◽  
Level Ii ◽  
Lack Of Knowledge

Abstract : Nursing students often experience stress or stress in undergoing clinical practice. There are several factors that cause students to experience stress, including lack of knowledge and skills, workloads and assignments, and the clinical environment itself. The purpose of this study was to determine the differences in stress levels of clinical practice students at level II and level III of Nursing Diploma III Program at STIKes Kepanjen. This type of research is descriptive quantitative with a causal comparative approach with a total of 60 respondents. Data analysis using Mann – Whitney so that the results show that there are significant differences in the level of stress level II and level III students in conducting clinical studies. While for the stressors of students who are undergoing clinical practice are lack of knowledge and skills, workload and assignments, hospital environment and when caring for patients. So that to achieve the goal of clinical learning is to prepare students both knowledge, skills and maturity in dealing with pressure when carrying out clinical learning.Keywords : Clinical practice, Nursing Student

Presbycusis, Part 1: Can You Hear the Music Of Life?

2012 ◽  
Vol 13 (3) ◽  
pp. 148-172 ◽  
Author(s):  
Barbara Hutchison ◽  
Eleanor K. Covan ◽  
Janet C. Bogus
Keyword(s):  
Hearing Loss ◽  
Pilot Study ◽  
Hearing Impairment ◽  
Problem Behaviors ◽  
Hearing Aids ◽  
Age Groups ◽  
Clinical Environment ◽  
Hearing Sensitivity ◽  
Novel Approach ◽  
Short Period

We used a novel approach allowing participants in this study to self-monitor their hearing sensitivity to familiar sounds in the environment. The objective of this approach was to establish whether participants in the 80–89 and 90–99 age groups would recognize the degree of their hearing impairment. It was our hope that participants would value audiology treatment and that it would improve their quality of life over a short period. The pilot study took place in a clinical environment where participants answered survey questions before and after audiology treatment, which pertained to their hearing impairment, morale, social support, and life satisfaction. Caregivers were included in the research to rate and record participants’ problem behaviors (e.g., shouting, anger, agitation, repetitive speech dialog, and depression) before, during, and after treatment. This research validates other scientists’ findings that annoying problem behaviors may actually be the result of hearing loss because of a person’s inability to recognize speech. The pilot study shows that participants with mild dementia adapted well to speech and sounds in the natural environment without agitation as well as to management of hearing aids within a 30-day period. The participants with moderate dementia were slower to adapt. All participants with dementia required the cooperation of their caregivers to maintain hygiene of ear canals and hearing aids and insertion. This study suggests that the sooner people receive treatment for hearing loss, the quicker they are to recognize speech and to master hearing aid technology.

Development of a portable cold air plasma jet device and observation of its photo ionization process

2020 ◽  
Vol 22 (8) ◽  
pp. 085403 ◽  
Author(s):  
Zhaoquan CHEN ◽  
Jinfang WU ◽  
Huang ZHANG ◽  
Ming ZHANG ◽  
Sanyang ZHANG ◽  
...  
Keyword(s):  
Plasma Jet ◽  
Ionization Process ◽  
Air Plasma ◽  
Cold Air ◽  
Photo Ionization
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