scholarly journals Probiotic Lactobacillus plantarum 299v Does Not Counteract Unfavorable Phytohemagglutinin-Induced Changes in the Rat Intestinal Microbiota

2008 ◽  
Vol 74 (16) ◽  
pp. 5244-5249 ◽  
Author(s):  
Gabriele Gross ◽  
Jessica Wildner ◽  
Arjan Schonewille ◽  
Jan L. W. Rademaker ◽  
Roelof van der Meer ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Population Structure ◽  
Lactobacillus Plantarum ◽  
Intestinal Microbiota ◽  
Intestinal Epithelium ◽  
Bacterial Population ◽  
Careful Evaluation ◽  
Probiotic Lactobacillus ◽  
Induced Changes

ABSTRACT Application of phytohemagglutinin (PHA) in weaning feed has been suggested to stimulate intestinal epithelium maturation. In this study, PHA strongly affected the fecal bacterial population structure of rats. Escherichia coli overgrowth was not prevented by probiotic mannose-adhering Lactobacillus plantarum 299v. Therefore, use of PHA in weaning feed deserves careful evaluation.

scholarly journals Evaluation of the Escherichia coli population in the intestinal microbiota of rattus wistar submitted to secondhand smoke and supplemented with prebiotics

2020 ◽  
Author(s):  
Bruna Rafaela dos Santos Silva ◽  
Paula Marioto Perez ◽  
Hermann Bremer Neto ◽  
Rogeria Keller
Keyword(s):  
Escherichia Coli ◽  
Intestinal Microbiota ◽  
Chronic Conditions ◽  
Functional Foods ◽  
Bacterial Population ◽  
Basal Diet ◽  
Control Group ◽  
Bacterial Populations ◽  
Beneficial Effects ◽  
Smoking Control

AbstractMany chronic conditions, including smoking, have been shown to be associated with modifications in the gut microbiota and to remedy the effects of these changes, functional foods such as prebiotics have shown beneficial effects. The aim of this work was to evaluate changes in the bacterial population of Escherichia coli in the intestinal microbiota of rats submitted to passive smoke and to the supplementation of prebiotics incorporated into the basal diet. The animals were divided into: Control Group (CG) = basal diet; Smoking Control Group (GCT) = basal diet with exposure to smoking; Prebiotic Group (GP) = basal diet incorporated with 1g of Immunowall® per kg of diet; Prebiotic Tobacco Group (GPT) = basal diet incorporated with 1g of ImmunowallTM per kg of diet with exposure to smoking. The animals were exposed to the smoke twice a day for 180 days. The obtained data were analyzed through the nonparametric Kruklla-Wallis test. Bacterial populations were amplified by real-time PCR. The results of this study revealed a significant decrease (p = 0.04 and p = 0.01) in Escherichia coli population in the group of animals supplemented with prebiotics in the intestinal microbiota of rats exposed and not exposed to cigarette smoke reinforcing the modulating effect of potential pathogens on the intestinal microbiota by functional foods.

Development of coconut water-based exopolysaccharide rich functional beverage by fermentation with probiotic Lactobacillus plantarum SVP2

2021 ◽  
pp. 102030
Author(s):  
Louella Concepta Goveas ◽  
K.S. Ashwath ◽  
Brejeth Renita Nazerath ◽  
Ostrin Dsouza ◽  
Ullekh ◽  
...  
Keyword(s):  
Lactobacillus Plantarum ◽  
Coconut Water ◽  
Probiotic Lactobacillus ◽  
Water Based

scholarly journals β-Elemene Suppresses Obesity-Induced Imbalance in the Microbiota-Gut-Brain Axis

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 704
Author(s):  
Yingyu Zhou ◽  
Wanyi Qiu ◽  
Yimei Wang ◽  
Rong Wang ◽  
Tomohiro Takano ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
High Fat Diet ◽  
Brain Regions ◽  
Cerebral Metabolites ◽  
The Central Nervous System ◽  
Cerebral Inflammation ◽  
Regulatory Effects ◽  
Induced Changes ◽  
Pearson Correlations ◽  
Glucose Cycle

As a kind of metabolically triggered inflammation, obesity influences the interplay between the central nervous system and the enteral environment. The present study showed that β-elemene, which is contained in various plant substances, had effects on recovering the changes in metabolites occurring in high-fat diet (HFD)-induced obese C57BL/6 male mice brains, especially in the prefrontal cortex (PFC) and hippocampus (HIP). β-elemene also partially reversed HFD-induced changes in the composition and contents of mouse gut bacteria. Furthermore, we evaluated the interaction between cerebral metabolites and intestinal microbiota via Pearson correlations. The prediction results suggested that Firmicutes were possibly controlled by neuron integrity, cerebral inflammation, and neurotransmitters, and Bacteroidetes in mouse intestines might be related to cerebral aerobic respiration and the glucose cycle. Such results also implied that Actinobacteria probably affected cerebral energy metabolism. These findings suggested that β-elemene has regulatory effects on the imbalanced microbiota-gut-brain axis caused by obesity and, therefore, would contribute to the future study in on the interplay between cerebral metabolites from different brain regions and the intestinal microbiota of mice.

scholarly journals Ecological Effect of Ceftaroline-Avibactam on the Normal Human Intestinal Microbiota

2015 ◽  
Vol 59 (8) ◽  
pp. 4504-4509 ◽  
Author(s):  
Mamun-Ur Rashid ◽  
Staffan Rosenborg ◽  
Georgios Panagiotidis ◽  
Karin Söderberg-Löfdal ◽  
Andrej Weintraub ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Intestinal Microbiota ◽  
Ecological Effect ◽  
New Combination ◽  
Plasma Samples ◽  
Ceftaroline Fosamil ◽  
Content Type ◽  
Human Intestinal Microbiota ◽  
Normal Human ◽  
Lactamase Inhibitor

ABSTRACTCeftaroline-avibactam is a new combination of the antibiotic ceftaroline with a novel non-β-lactam β-lactamase inhibitor, avibactam. The purpose of the present study was to investigate the effect of ceftaroline-avibactam on the human intestinal microbiota. Fourteen healthy volunteers received ceftaroline-avibactam (600 mg ceftaroline fosamil and 600 mg avibactam) intravenously over 2 h every 8 h on days 1 to 6 and as a single dose on day 7. Fecal samples were collected on day −1 (within 24 h of the first infusion on day 1) and on days 2, 5, 7, 9, 14, and 21.Escherichia colinumbers decreased during the study and normalized on day 21. An increased number ofKlebsiellabacteria appeared on day 14 and normalized on day 21. The number of other enterobacteria decreased during the study, and the number of enterococci decreased from days 2 to 7 and normalized on day 9.Candidanumbers increased from days 5 to 9 and normalized after day 14. The number of lactobacilli decreased during the study and recovered on day 14. The number of bifidobacteria decreased on day 2 and normalized on day 21. The number ofBacteroidesbacteria was unchanged.Clostridium difficilenumbers decreased on days 7 and 9 and increased on days 14 and 21. A toxigenicC. difficilestrain was detected in one volunteer on day 21 with no reported adverse events. Plasma samples were collected on days −1, 2, 5, and 7. Ceftaroline and avibactam concentrations were 0 to 34.5 mg/liter and 0 to 61.6 mg/liter, respectively, in plasma and 0 to 35.4 mg/kg and 0 to 98.5 mg/kg, respectively, in feces. (This study is registered in the European Clinical Trials Database [https://eudract.ema.europa.eu/] under number EudraCT 2012 004921-25.)

scholarly journals Complete Genome Sequence of the Probiotic Lactobacillus plantarum ST-III

2010 ◽  
Vol 193 (1) ◽  
pp. 313-314 ◽  
Author(s):  
Y. Wang ◽  
C. Chen ◽  
L. Ai ◽  
F. Zhou ◽  
Z. Zhou ◽  
...  
Keyword(s):  
Lactobacillus Plantarum ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Probiotic Lactobacillus

scholarly journals Promoter/repressor system of Lactobacillus plantarum phage øg1e: characterization of the promoters pR49–pR–pL and overproduction of the Cro-like protein Cng in Escherichia coli

Gene ◽  
1998 ◽  
Vol 215 (2) ◽  
pp. 371-379 ◽  
Author(s):  
Makiko Kakikawa ◽  
Nobukatsu Watanabe ◽  
Tatsuya Funawatashi ◽  
Masaya Oki ◽  
Hiroo Yasukawa ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Lactobacillus Plantarum
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